Fujita Ken'ichi

フジタケンイチ | Fujita Ken'ichi

Affiliation and department：
Job title： Professor
Homepage URL (1)： https://www.omu.ac.jp/sci/biol-mbiol/

Research field (2)： Applied microbiology , Pharmaceuticals - health and biochemistry

Research keywords (4)：バイオポリマー:ポリグルタミン酸の物性、生合成機構およびその生理活性 , 真菌における薬剤耐性機構およびそれを標的とする生理活性物質 , 抗真菌性抗生物質の探索およびその作用機序 , 抗真菌、薬剤耐性、ポリグルタミン酸

Research theme for competitive and other funds (16)：

2022 - 2025 Exploration of promising molecules derived from antimycin antibiotics with suppressive activity towards the production of inflammatory cytokines
2021 - 2024 真菌の薬剤排出ポンプ過剰発現における小胞体の役割
2016 - 2019 薬剤誘導型酸化ストレスによる薬剤排出ポンプの活性および遺伝子発現の制御
2016 - 2017 フェニルプロパノイド類を用いる薬剤排出ポンプ調節機構の解析
2013 - 2016 薬剤排出ポンプ遺伝子群の発現制御へのカルシウムシグナルの関与

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Papers (129)：

Yoshinosuke Usuki, Ryota Abe, Kazuki Nishiguchi, Tetsuya Satoh, Harumi Aono, Toshihiko Nogawa, Yushi Futamura, Hiroyuki Osada, Izumi Yoshida, Kazuhiro Fujita, et al. Total Synthesis, Stereochemical Assignment, and Biological Evaluation of Opantimycin A and Analogues Thereof. Organic & Biomolecular Chemistry. 2024. In press
Ilhamzah, Yuka Tsukuda, Yoshihiro Yamaguchi, Akira Ogita, Ken-ichi Fujita. Persimmon tannin promotes the growth of Saccharomyces cerevisiae under ethanol stress. Journal of the Science of Food and Agriculture. 2024. In press
Naoko Mizuhara, Moe Inoue, Hideki Kurotaki, Kazuyori Matsumoto, Akira Ogita, Ken-Ichi Fujita. Pterostilbene, a natural methoxylated analogue of resveratrol, exhibits antifungal activity induced by reactive oxygen species production and plasma membrane injury. Applied Microbiology. 2023. 3. 3. 666-674
S. Yamano, Y. Tsukuda, N. Mizuhara, Y. Yamaguchi, A. Ogita, K. Fujita. Dehydrozingerone enhances the fungicidal activity of glabridin against Saccharomyces cerevisiae and Candida albicans. Letters in Applied Microbiology. 2023. 76. 4. ovad040
Y. Tsukuda, N. Mizuhara, Y. Usuki, Y. Yamaguchi, A. Ogita, T. Tanaka, K. Fujita. Structure-activity relationships of antifungal phenylpropanoid derivatives and their synergy with n-dodecanol and fluconazole. Letters in Applied Microbiology. 2022. 74. 3. 377-384

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MISC (55)：

Ogita Akira, Fujita Ken-ichi, Yamaguchi Yoshihiro, Yamauchi Ken, Tanaka Toshio. 3P-271 Enhancement of antimicrobial activity of parabens by sulforaphane, an isothiocyanate from broccoli. 2015. 67. 338-338
Nakano Taichi, Tomiyama Takashi, Inoi Takahiro, Yoshida Izumi, Mishima Takashi, Takahashi Ryosuke, Kitamura Shinichi, Ogita Akira, Tanaka Toshio, Fujita Ken-ichi. 3P-096 Effect of poly (gamma-glutamic acid) on IL-12 gene transcript level against macrophage-like cell line THP-1. 2015. 67. 294-294
藤田憲一. アネトールが示す相乗的抗真菌作用の発現メカニズム. Aroma Research. 2014. 15. 4. 362-363
Kang Chang-Kyung, Yamada Keiichi, Ogita Akira, Fujita Ken-ichi, Tanaka Toshio. 2P-215 Enhancement effect of N-methyl-N"-dodecylguanidine on the vacuole disruptive action of amphotericin B. 2014. 66. 160-160
Shima Tomoki, Tomiyama Takashi, Mizuhara Naoko, Usuki Yoshinosuke, Liu Tao, Azuma Masayuki, Ogita Akira, Tanaka Toshio, Fujita Ken-ichi. 2P-235 Effect of poly(gamma-glutamic acid) on IL-12 production against J774.1 macrophage-like cell line. 日本生物工学会大会講演要旨集. 2014. 66. 165-165

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Patents (6)：

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Books (4)：

第4章第7節:植物由来の薬剤排出ポンプ阻害剤による抗菌剤・防腐剤の使用量低減化への試み
「食品・化粧品・医薬品への保存料・防腐剤の最適な配合法」, (株)技術情報協会 2014
第1章第2節:[9]防腐剤/抗菌剤の効果増強剤としての天然由来成分の活用法
「食品・化粧品・医薬品への保存料・防腐剤の最適な配合法」, (株)技術情報協会 2014
Anti-Salmonella agents from the Brazilian medicinal plant Tanacetum balsamita and their applications
Natural Antioxidants and Biocides from Wild Medicinal Plants (eds C.L. Cespedes et al.) CAB International 2013
Naturally Occurring antifungal agents and their modes of action
Fungicides for Plant and Animal Diseases. Edited by: D. Dhanasekaran, N. Thajuddin and A. Panneerselvam Publisher: InTech 2012

Lectures and oral presentations (74)：

出芽酵母におけるミトコンドリアの融合・分裂とチューブリンの関係
(第76回日本生物工学会大会 2024)
梨幼果抽出成分による出芽酵母の寿命延伸効果と寿命関連遺伝子の発現
(第76回日本生物工学会大会 2024)
The role of persimmon tannin in growth and metabolism of yeast under ethanol stress
(76th SBJ Meeting (2024) 2024)
熱処理がポリグルタミン酸の分子構造と免疫賦活効果に与える影響
(第76回日本生物工学会大会 2024)
出芽酵母における微小管脱重合阻害剤添加によるミトコンドリア形態異常
(日本農芸化学会 2024 年度大会 2024)

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Education (4)：

Professional career (1)：

Work history (5)：

2024/04 - 現在 Osaka Metropolitan University School of Science Department of Biology Professor
2024/04 - 現在 Osaka Metropolitan University Graduate School of Science Department of Biology Professor
1996/04/01 - 現在 Osaka City University Graduate School of Science Biology and Geosciences Course Associate Professor
2022/04 - 2024/03 Osaka Metropolitan University School of Science Department of Biology Associate Professor
2003 - Osaka City University

Association Membership(s) (3)：

酵母遺伝学フォーラム , 日本農芸化学会 , THE SOCIETY FOR BIOTECHNOLOGY, JAPAN

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