Rchr
J-GLOBAL ID:200901050617110496
Update date: Nov. 28, 2024
Yoshiba Nagako
ヨシバ ナガコ | Yoshiba Nagako
Affiliation and department:
Research field (1):
Conservative dentistry and endodontics
Research theme for competitive and other funds (33):
- 2024 - 2026 マクロファージの表現型に影響する細胞外基質ラミニンの機能解析
- 2022 - 2026 Functional analysis of extracellular matrix laminin affecting macrophage phenotype
- 2021 - 2024 歯髄の創傷治癒・再生過程におけるGli1陽性幹細胞の動態と分化誘導機構の解明
- 2019 - 2022 ヒト歯髄の創傷治癒過程におけるM2マクロファージとシュワン細胞の相互作用の解明
- 2021 - 2022 シュワン細胞がマクロファージを神経保護作用を有する表現型に誘導する機序の解明
- 2019 - 2020 The clarification of the pulp generation mechanism to improve the odontoblast differentiation by the transporter of ascorbic acid.
- 2016 - 2020 A study on the mechanisms of induction and differentiation of stem cells during wound healing and regeneration of dentin-pulp complex
- 2016 - 2019 Role of alpha-SMA expressing cells in dental pulp wound healing and regeneration
- 2014 - 2017 Regeneration of rat molar pulp tissue by the implantation of stem cells from incisor pulp: development of a rat model of autologous pulp tissue engineering
- 2013 - 2016 Contribution of Myofibroblasts in Dental Pulp Healing and Regeneration
- 2013 - 2015 Application of activated macrophages derived from dental pulp stem cells to dental pulp tissue engineering
- 2012 - 2015 A study on the mechanisms of tissue wound healing and regeneration of dental pulp
- 2011 - 2014 Dental pulp regeneration by stem cell transplantation: development of scaffolds and establishment of an animal experimental model
- 2011 - 2012 Elucidation of the mechanism of post-repantation replacement resorption as a basis for the development of periodontal ligament regeneration therapy
- 2010 - 2012 Degradation and down-regulation of fibrillin-1 during wound healing of human dental pulp tissue
- 2009 - 2011 A study on the mechanisms of tissue repair and regeneration of dentin-pulp complex
- 2008 - 2010 Pathogenic mechanisms in apical periodontitis : innate immunity, acquired immunity and dendritic cell maturation
- 2007 - 2009 A study of pulpal responses to laser irradiation
- 2007 - 2008 歯内歯周疾患の病態形成機序-新規疾患モデルを用いた樹状細胞の動態解析
- 2006 - 2008 A study on mechanisms of tissue repair and regeneration of the dentin-pulp complex
- 2005 - 2007 Immune defense mechanisms of the dentin/pulp complex: Immunohistochemical analysis on the heterogeneity and kinetics of dendritic cells
- 2004 - 2006 Evaluation of pulpal responses to GaAIAs laser irradiation.
- 2004 - 2005 A study on mechanisms of tissue formation and regeneration of the dentin-pulp complex
- 2002 - 2003 A study on mechanisms of tissue repair and regeneration of the dentin-pulp complex
- 2001 - 2002 う蝕修復処置後の歯髄反応に関する免疫組織化学的研究
- 1998 - 2000 A study on mechanisms of odontoblast differentiation during reparative dentinogenesis.
- 1998 - 1999 生体親和性歯髄保護材の開発に関する基礎的研究
- 歯牙形成における上皮-間葉相互作用に関する研究
- 歯牙形成ならびに被蓋硬組織(dentin bridge)形成に関する研究
- 生体親和性材料に対する歯髄反応に関する研究
- Epithelial-mesenchymal interactions during tooth development
- Study on tooth development and dentin bridge formation
- Study on Pulpal Response to Biomaterials
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Papers (73):
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Akihiro Hosoya, Hiroaki Takebe, Yuri Seki-Kishimoto, Yukiko Noguchi, Tadashi Ninomiya, Akira Yukita, Nagako Yoshiba, Ayako Washio, Masahiro Iijima, Takahiko Morotomi, et al. Polycomb protein Bmi1 promotes odontoblast differentiation by accelerating Wnt and BMP signaling pathways. Histochemistry and cell biology. 2024. 163. 1. 11-11
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Yuka Aizawa, Kenta Haga, Nagako Yoshiba, Witsanu Yortchan, Sho Takada, Rintaro Tanaka, Eriko Naito, Tatsuya Abé, Satoshi Maruyama, Manabu Yamazaki, et al. Development and Characterization of a Three-Dimensional Organotypic In Vitro Oral Cancer Model with Four Co-Cultured Cell Types, Including Patient-Derived Cancer-Associated Fibroblasts. Biomedicines. 2024. 12. 10
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Kridtapat Sirisereephap, Hikaru Tamura, Jong-Hyung Lim, Meircurius Dwi Condro Surboyo, Toshihito Isono, Takumi Hiyoshi, Andrea L. Rosenkranz, Yurie Sato-Yamada, Hisanori Domon, Akari Ikeda, et al. A novel macrolide-Del-1 axis to regenerate bone in old age. iScience. 2024. 27. 2. 108798-108798
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Naoki Edanami, Shouji Takenaka, Razi Saifullah, Ibn Belal, Kunihiko Yoshiba, Shintaro Takahara, Nagako Yoshiba, Naoto Ohkura, Yuichiro Noiri. In Vivo assessment of the Apatite-Forming Ability of New-Generation Hydraulic Calcium Silicate Cements Using a Rat Subcutaneous Implantation Model. Journal of Functional Biomaterials. 2023. 14. 4
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Naoki Edanami, Razi Saifullah Ibn Belal, Shoji Takenaka, Kunihiko Yoshiba, Rosa Edith Baldeon Gutierrez, Shintaro Takahara, Nagako Yoshiba, Naoto Ohkura, Yuichiro Noiri. In Vivo Assessment of the Calcium Salt-Forming Ability of a New Calcium Silicate-Based Intracanal Medicament: Bio-C Temp. Dentistry journal. 2023. 11. 4
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MISC (105):
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高原信太郎, 大倉直人, 吉羽邦彦, 吉羽永子, 竹中彰治, 枝並直樹, 庭野和明, 野杁由一郎. The comparison analyses of wound-healing mechanism according to the root development stage using the regeneration model rats. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 158th
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高原信太郎, 大倉直人, 吉羽永子, 竹中彰治, 枝並直樹, 吉羽邦彦, 野杁由一郎. The localization of various mesenchymal stem cell marker-positive cells in early healing stage after regenerative endodontic procedure. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 159th
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大倉直人, 大倉直人, 吉羽永子, 高原信太郎, GUTIERREZ Rosa Edith Baldeon, GOMEZ-KASIMOTO Susan, 井田貴子, 枝並直樹, 竹中彰治, 吉羽邦彦, et al. Impact of the tissue nonspecific alkaline phosphatase during the root formation. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 159th
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高原信太郎, 枝並直樹, 竹中彰治, 吉羽邦彦, 大倉直人, 吉羽永子, 野杁由一郎. Interactions between Apically-extruded Bioceramic Sealers and periodontal tissues. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2022. 157th
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枝並直樹, 竹中彰治, 吉羽邦彦, 大倉直人, 吉羽永子, 高原信太郎, 野杁由一郎. Comparison of Biomineralization Ability of Calcium Silicate-based and Calcium Hydroxide-based Intracanal Medicaments. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2022. 157th
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Books (6):
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Distribution of noncollagenous proteins during reparative dentinogenesis in human teeth.
Dentin/Pulp Comples:Proceeding of the International Conference on Dentin/Pulp Complex 2001. 2002
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Distribution of concollagenous proteins during reparative dentinogensis in human teeth.
Dentin/Pulp Comples:Proceeding of the International Conference on Dentin/Pulp Complex 2001. 2002
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Distribution of the small proteoglycan decorin in human teeth. (共著)
Dentin/Pulp Complex : Proceedings of the International Conference on Dentin/Pulp Complex 1995. Quintessence Publishing Co. 1996
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Distribution of odontoblast processes in human coronal dentin. (共著)
Dentin/Pulp Complex : Proceedings of the International Confernce on Dentin/Pulp Complex 1995. Quintessence Publishing Co. 1996
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Hard tissue formation in subcutaneously transplanted rat molars.
Dentin/Pulp Complex:Proceeding of the International Conference on Dentin/Pulp Complex 2001. Quintessence Publishing Co.
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Lectures and oral presentations (2):
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Differences in affinity between laminin isoforms and their integrins affect macrophage phenotype
(The 97th Annual Meeting of the Japanese Biochemical Society 2024)
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Integrin α7 regulates the differentiation of THP-1 macrophages into dendritic cells
(The 56th Annual Meeting of the Japanese Society for Matrix Biology and Medicine 2024)
Education (2):
- - 1989 Niigata University Faculty of Dentistry School of Dentistry
- - 1989 Niigata University Faculty of Dentistry
Professional career (1):
Work history (9):
- 2024/04 - 現在 新潟大学大学院医歯学総合研究科 口腔保健学分野 教授
- 2022/11 - 2024/03 Niigata University
- 2009/04 - 2024/03 新潟大学医歯学総合病院 講師
- 2021/04 - 2022/03 2021年度拠点事業「大阪大学蛋白質研究所共同研究員」
- 2000/01 - 2009/03 新潟大学歯学部 助手
- 2002/04 - 2003/01 日本学術振興会海外特別研究員 ルイパスツール・ストラスブルブ大学(フランス)
- 1997/04 - 1999/12 日本学術振興会特別研究員(PD)
- 1995/11 - 1996/10 ルイパスツール・ストラスブルグ大学(フランス)リサーチフェロー
- 1989/04 - 1995/10 新潟大学歯学部付属病院 医員
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Awards (4):
- 2021/12 - 新潟大学 令和3年度新潟大学優秀論文賞
- 2014 - 日本歯科保存学会 学術賞
- 1998 - 日本歯科保存学会 奨励賞
- 1995 - 財団法人山下太郎 海外派遣助成賞
Association Membership(s) (6):
日本結合組織学会
, 日本生化学会
, ORCA
, 新潟歯学会
, 日本歯科保存学会
, 歯科基礎医学会
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