2019 - 2022 Effects of membrane tension and membrane potential on the function of antimicrobial peptides and cell-penetrating peptides and their mechanisms
2015 - 2018 Elucidation of the mechanisms of functions of antimicrobial peptides and cell-penetrating peptides using the single giant unilamellar vesicle (GUV) method
2009 - 2012 Study on interactions of proteins/peptides disrupting cell membranes with lipid membranes using the single giant unilamellar vesicle method
2003 - 2005 Mechanical Property of Single Filamin A Molecules and the Mechanism for Function of Actin/Filamin A Gel
2002 - 2003 in vivo Dynamics of filamin A-crosslinked actin-based cytoskeletons and function of their mechanical responses
1999 - 2000 Study for mechanical properties of an actin-gelation protein, ABP-280 by the single-molecule manipulation
1995 - 1997 Synthesis and Structure-Function Relationship Study of Pore Structures emulated Ligand-gated Ionic Channel
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Papers (168):
Md. Zahidul Islam, Farzana Hossain, Md Hazrat Ali, Masahito Yamazaki. Relationship between antimicrobial peptides-induced cell membrane damage and bactericidal activity. Biophysical Journal. 2023. in press
Kanta Tazawa, Masahito Yamazaki. Effect of Monolayer Spontaneous Curvature on Constant Tension-induced Pore Formation in Lipid Bilayers. J. Chem. Phys. 2023. 081101
Md. Masum Billah, Md. Mamun Or Rashid, Marzuk Ahmed, Masahito Yamazaki. Antimicrobial peptide magainin 2-induced rupture of single giant unilamellar vesicles comprising E. coli polar lipids. BBA - Biomembranes. 2022. 184112
Moynul Hasan, Farzana Hossain, Hideo Dohra, Masashito Yamazaki. Role of Interfacial Hydrophobicity in Antimicrobial Peptide Magainin 2-induced Nanopore Formation. Biochem. Biophys. Res. Commun. 2022. 630. 50-56
Farzana Hossain, Md Masum Billah, Masahito Yamazaki, Silvia T. Cardona. Single-Cell Analysis of the Antimicrobial and Bactericidal Activities of the Antimicrobial Peptide Magainin 2. Microbiology Spectrum. 2022
Sayed Ul Alam Shibly, Chiranjib Ghatak, Mohammad Abu Sayem Karal, Md. Moniruzzaman, Masahito Yamazaki. Experimental Estimation of Membrane Tension Induced by Osmotic Pressure (vol 111, pg 2190, 2016). BIOPHYSICAL JOURNAL. 2017. 112. 6. 1290-1290
Sabrina Sharmin, Md Zahidul Islam, Masahito Yamazaki, Hideo Dohra. Effects of Lipid Compositions on the Entry of Cell Penetrating Peptide Oligoarginine into Single Vesicles. BIOPHYSICAL JOURNAL. 2017. 112. 3. 379A-379A
Oka Toshihiko, Tsuboi Taka-aki, Saiki Takahiro, Takahashi Tomoki, Yamazaki Masahito. 28aAC-7 Electrostatic Interaction-Induced Transition between Cubic Phase and Liquid-Crystalline Phase in Biological Lipid Membranes. Meeting abstracts of the Physical Society of Japan. 2014. 69. 1. 406-406
Tamba Y., Yamazaki M. 28pVC-8 Magainin 2-Induced Pore Formation in Membrane Depends on its Concentration in Membrane Interface. Meeting abstracts of the Physical Society of Japan. 2009. 64. 1. 373-373
Tamba Y., Ariyama H., Yamazaki M. 23aYD-3 Effects of Surface Charge Density of Lipid Membranes on the Pore Formation Induced by Antimicrobial Peptide, Magainin 2. Meeting abstracts of the Physical Society of Japan. 2008. 63. 1. 351-351
Single-cell analysis of the antimicrobial and bactericidal activities of the antimicrobial peptides
(令和4年度生体医歯工学共同拠点 成果報告会 2023)
Single-cell analysis of the antimicrobial and bactericidal activities of the antimicrobial peptide magainin 2
(The 7th International Symposium on Biomedical Engineering 2022)
Effect of osmotic pressure on antimicrobial peptide magainin 2-induced pore formation and its evolution
(The 7th International Symposium on Biomedical Engineering 2022)
Effect of lipid composition and distribution on constant tension-induced pore formation in GUVs
(日本生物物理学会第60回年次大会 2022)