KATO Mitsuyasu

カトウミツヤス | KATO Mitsuyasu

Affiliation and department：
Job title： Executive Director

Research field (3)： Human pathology , Experimental pathology , Tumor biology

Research keywords (15)： Special Macrocyclic Peptide , β-catenin , Wnt , THG-1 (TSC22D4) , Tsc-22 , GPNMB , MafK , C18ORF1 , TMEPAI , Smad , TGF-β (transforming growth factor-β) , 3D quantitative histopathology , tissue stem cell , Cancer Stem Cell , Cancer

Research theme for competitive and other funds (34)：

2018 - 2023 Induction of Cancer Stem Cell Properties by GPNMB
2017 - 2019 休止状態の乳がん幹細胞を標的とするがん治療薬・再発抑制薬の開発
2014 - 2019 特殊環状ペプチドを中核とした革新的次世代バイオ医薬品開発の加速
2014 - 2016 足場非依存性間欠性細胞分裂の転写制御と代謝
2013 - 2016 Roles of TGF-beta target genes TMEPAI and MafK on cancer development

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Papers (139)：

Yoon, Jeong-Hwan, Bae, Eunjin, Nagafuchi, Yasuo, Sudo, Katsuko, Han, Jin Soo, Park, Seok Hee, Nakae, Susumu, Yamashita, Tadashi, Ju, Ji Hyeon, Matsumoto, Isao, et al. Repression of SMAD3 by STAT3 and c-Ski induces conventional dendritic cell differentiation. Life science alliance. 2024. 7. 9
Kimura, Tomokazu, Okita, Yukari, Nagumo, Yoshiyuki, Chin, Jas Min, Fikry, Muhammad Ali, Shiga, Masanobu, Kandori, Shuya, Kawahara, Takashi, Suzuki, Hiroyuki, Nishiyama, Hiroyuki, et al. Glycoprotein nonmetastatic melanoma protein B impacts the malignant potential of bladder cancer cells through its hem-immunoreceptor tyrosine-based activation motif. PATHOLOGY INTERNATIONAL. 2024. 74. 5. 262-273
Goto, Nohara, Suzuki, Hiroyuki, Zheng, Ling, Okano, Yasuhito, Okita, Yukari, Watanabe, Yukihide, Kato, Yukinari, Kato, Mitsuyasu. Promotion of squamous cell carcinoma tumorigenesis by oncogene-mediated THG-1/TSC22D4 phosphorylation. CANCER SCIENCE. 2023. 114. 10. 3972-3983
Tzavlaki, Kalliopi, Ohata, Yae, Morén, Anita, Watanabe, Yukihide, Eriksson, Jens, Tsuchiya, Maiko, Kubo, Yuki, Yamamoto, Kouhei, Sellin, Mikael E, Kato, Mitsuyasu, et al. The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition. JOURNAL OF CELLULAR PHYSIOLOGY. 2023. 238. 4. 790-812
Uchida, Yoshimi, Nakano, Naoko, Itoh, Fumiko, Watanabe, Yukihide, Taketo, Makoto M, Kato, Mitsuyasu, Itoh, Susumu. Suppression of intestinal tumorigenicity by loss of TMEPAI family genes. CANCER SCIENCE. 2023. 114. 1:SI. 2056-2056

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Patents (1)：

新規なレポータープラスミド

Books (10)：

解明病理学病気のメカニズムを解く第4版
医歯薬出版株式会社 2021 ISBN:9784263732038
解明病理学病気のメカニズムを解く
医歯薬出版株式会社 2017 ISBN:9784263731789
NEWエッセンシャル病理学第6版
医歯薬出版 2009
Negative regulation of the TGF-β family signal pathway by inhibitory Smads and their involvement in cancer and fibrosis.
Humana Press Inc. 2008
ルービン病理学第2章炎症
西村書店 2007

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Lectures and oral presentations (244)：

GPNMBによるがん幹細胞性誘導を介した腫瘍形成機構の解明
(第83回日本癌学会学術総会)
空間的トランスクリプトーム解析を用いたトリプルネガティブ乳癌に対する治療標的分子の探索
(第83回日本癌学会学術総会)
トリプルネガティブ乳癌における非転移性メラノーマタンパク質 B による腫瘍免疫制御機構
(第83回日本癌学会学術総会)
乳がんの進展におけるglycoprotein NMBの作用
(第113回日本病理学会総会)
Role of GPNMB in acquisition of cellular motility
(第82回日本癌学会学術総会)

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Education (1)：

- 1985 Tohoku University, School of Medicine School of Medicine

Professional career (1)：

Doctor of Medical Sciences (Tohoku University)

Work history (9)：

2021/04 - 現在筑波大学本部副学長・理事
2011/10 - 現在 University of Tsukuba Faculty of Medicine Professor
2018/04 - 2021/03 University of Tsukuba Faculty of Medicine Dean
2004/04 - 2011/09 University of Tsukuba Graduate School of Comprehensive Human Sciences Professor
2002/04 - 2004/03 University of Tsukuba Institute of Basic Medical Sciences Professor

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Committee career (2)：

2018/04 - 現在日本病理学会研究推進委員会委員
1995 - 現在日本病理学会学術評議員

Awards (1)：

2000/12 - 日本病理学会日本病理学会学術研究賞(A演説)

Association Membership(s) (3)：

The Molecular Biology Society of Japan , The Japanese Cancer Association , THE JAPANESE SOCIETY OF PATHOLOGY

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