Isono Takahiro

イソノタカヒロ | Isono Takahiro

Affiliation and department：

Research field (1)： Molecular biology

Research keywords (1)：腫瘍診断学

Research theme for competitive and other funds (11)：

2017 - 2020 Elucidation of the mechanism of antitumor effect in inhibition of GGCT expression using integrated omics analysis
2015 - 2018 The exploratory research of biomarkers of renal cell carcinomas for therapeutic drugs based on the evidence of global transcriptome analysis.
2013 - 2016 Novel biomarker and therapeutic target in the targeted therapy for the patients with metastatic renal cell cancer
2011 - 2014 Application of novel clinicopathological biomarkers to cancer treatment
2010 - 2012 Analysis and clinical application of DNMT3L, a novel marker for human embryonal carcinoma

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Papers (94)：

Takahiro Isono, Takehiro Matsumoto, Masafumi Suzaki, Shigehisa Kubota, Susumu Kageyama, Akihiro Kawauchi, Atuyuki Wada. Transcriptome analysis of a dog model of congestive heart failure shows that collagen-related 2-oxoglutarate-dependent dioxygenases contribute to heart failure. Scientific reports. 2022. 12. 1. 22569-22569
窪田成寿, 礒野高敬, 吉田哲也, 影山進, 成田充弘, 河内明宏. オミックス解析に基づくGGCT発現阻害による抗腫瘍メカニズムの解明と膀胱癌治療への応用. 日本泌尿器科学会総会. 2021. 109回. OP18-06
Shigehisa Kubota, Tetsuya Yoshida, Susumu Kageyama, Takahiro Isono, Takeshi Yuasa, Junji Yonese, Ryoji Kushima, Akihiro Kawauchi, Tokuhiro Chano. A risk stratification model based on four novel biomarkers predicts prognosis for patients with renal cell carcinoma. World Journal of Surgical Oncology. 2020. 18. 1. 270-270
窪田成寿, 礒野高敬, 永澤誠之, 和田晃典, 影山進, 河内明宏. トランスクリプトーム解析を用いたGGCT発現阻害による抗腫瘍メカニズムの解明. 日本癌学会総会記事. 2020. 79回. PJ7-6
窪田成寿, 礒野高敬, 吉田哲也, 影山進, 成田充弘, 茶野徳宏, 湯浅健, 米瀬淳二, 河内明宏. 遺伝子発現データ解析に基づく腎細胞癌のバイオマーカーの同定とリスクモデルの構築. 日本癌治療学会学術集会抄録集. 2019. 57回. P37-7

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MISC (21)：

Susumu Kageyama, Hiromi Ii, Keiko Taniguchi, Shigehisa Kubota, Tetsuya Yoshida, Takahiro Isono, Tokuhiro Chano, Taku Yoshiya, Kosei Ito, Tatsuhiro Yoshiki, et al. Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase (GGCT): A Novel Molecular Target for Anticancer Therapy. International journal of molecular sciences. 2018. 19. 7
Takahiro Isono, Tokuhiro Chano, Tetsuya Yoshida, Susumu Kageyama, Akihiro Kawauchi, Junji Yonese, Takeshi Yuasa. Abundance of TRAIL attenuated by HIF2a and c-FLIP affects malignancy in renal cell carcinomas. Oncotarget. 2018. 9. 33. 23091-23101
影山進, 花田英紀, 窪田成寿, 富田圭司, 村井亮介, 小林憲市, 飯居宏美, 中田晋, 吉矢拓, 礒野高敬, et al. 新規癌増殖因子GGCT/C7orf24を標的とした抗がん剤の開発小規模プロテオーム解析からの挑戦. 日本泌尿器科学会総会. 2017. 105回. OP63-1
Takahiro Isono, Tokuhiro Chano, Tetsuya Yoshida, Susumu Kageyama, Akihiro Kawauchi, Masafumi Suzaki, Takeshi Yuasa. Hydroxyl-HIF2-alpha is potential therapeutic target for renal cell carcinomas. AMERICAN JOURNAL OF CANCER RESEARCH. 2016. 6. 10. 2263-2276
Takehiro Matsumoto, Atsuyuki Wada, Masanori Fujii, Atsuhi Taniguchi, Kousuke Mori, Yuichiro Tamagawa, Takahiro Isono, Minoru Horie. Next Generation Sequencing of Cardiac Gene Expression Changes Associated With Heart Failure in Chronic Inflammation Inhibition. CIRCULATION. 2014. 130

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Education (4)：

Professional career (1)：

Work history (4)：

Association Membership(s) (2)：

日本分子生物学会 , 日本癌学会

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