Rchr
J-GLOBAL ID：200901052974262558
Update date: Jun. 14, 2024
Nakazawa Mitsuru
ナカザワ ミツル | Nakazawa Mitsuru
Affiliation and department：
Job title：
Guest Researcher
Homepage URL (1)：
http://www.med.hirosaki-u.ac.jp/~ophthal/
Research field (1)：
Ophthalmology
Research keywords (2)：
眼科学
, Ophthalmology
Research theme for competitive and other funds (26)：
- 2019 - 2023 視細胞保護を目的とした新規カルパイン抑制ペプチド徐放システムの開発
- 2016 - 2019 網膜色素変性に対するカルパイン分子標的を応用した新規治療法
- 2013 - 2016 Strategy of photoreceptor protective treatment for retinitis pigmentosa
- 2012 - 2015 視細胞保護を目指した新たな分子標的療法
- 2009 - 2012 網膜色素変性の臨床像におよぼす加齢黄斑変性関連遺伝子多型の影響
- 2006 - 2008 Identification of molecular pathology of retinal degeneration
- 2005 - 2007 常染色体優性網膜色素変性原因遺伝子の発現調節を用いた視細胞変性機序の解析
- 2005 - 2006 新規の網膜細胞障害判定システムの確立:網膜変性に対する新しい治療法確立を目指して
- 2003 - 2005 網膜変性の修飾因子としての視細胞特異的カルシウム結合タンパクの効果
- 2004 - 2005 Study of effects of antiglaucoma eye drops on glaucomatous optic neuropathy and ocular serface.
- 2003 - 2005 New drug therapy for retinal degeneration using calcium channel blockers
- 2002 - 2004 遺伝性網膜変性症の分子病態にもとづく新しい薬物治療の有効性
- 2003 - 2004 遺伝子導入による新しい薬剤効果増強法を用いた緑内障に対する神経保護治療の開発(抗緑内障薬nipradilolの持つNO作用の増強を目指して)
- 2002 - 2003 網膜変性のmodifierとしてのサイトカインと光トランスダクション異常の役割
- 2002 - 2003 Study of autoimmune mechanisms in molecular pathology of glaucomatous optic neuropathy.
- 2000 - 2002 網膜の加齢変化におよぼすミトコンドリア遺伝子変異
- 2000 - 2002 網膜への新しい遺伝子導入法
- 2001 - 2002 Study of molecular pathology of rat model with inherited retinal degeneration
- 1999 - 2001 網膜色素変性および類縁疾患の病態解明と治療法に関する研究
- 1997 - 2000 網膜色素変性の原因遺伝子検索
- 1993 - 1995 網膜色素変性症の原因解明のための分子生物学的研究
- 1991 - 1993 網膜色素変性症の原因解明のための分子生物学的研究
- 1989 - 1991 網膜疾患における抗網膜抗体に関する研究
- 1989 - 1990 Molecular Biological Research for Hereditary Retinal Degeneration
- 1985 - Ophthalmic molecular genetics
- 1982 - Biochemistry of Retinal diseases
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Papers (35)：
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Taimu Sato, Koji M. Nishiguchi, Kosuke Fujita, Fuyuki Miya, Takashi Inoue, Erika Sasaki, Toshifumi Asano, Satoru Tsuda, Yukihiro Shiga, Hiroshi Kunikata, et al. Serum anti-recoverin antibodies is found in elderly patients with retinitis pigmentosa and cancer. Acta Ophthalmologica. 2020. 98. 6. e722-e729
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Koji M. Nishiguchi, Yasuhiro Ikeda, Kosuke Fujita, Hiroshi Kunikata, Makoto Akiho, Kazuki Hashimoto, Katsuhiro Hosono, Kentaro Kurata, Yoshito Koyanagi, Masato Akiyama, et al. Phenotypic Features of Oguchi Disease and Retinitis Pigmentosa in Patients with S-Antigen Mutations: A Long-Term Follow-up Study. Ophthalmology. 2019. 126. 11. 1557-1566
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Eriko Sugano, Kitako Tabata, Tsubasa Takezawa, Raki Shiraiwa, Hiroki Muraoka, Tomomi Metoki, Asaka Kudo, Yuki Iwama, Mitsuru Nakazawa, Hiroshi Tomita. N-Methyl-N-Nitrosourea-Induced Photoreceptor Degeneration Is Inhibited by Nicotinamide via the Blockade of Upstream Events before the Phosphorylation of Signalling Proteins. BioMed research international. 2019. 2019. 3238719-3238719
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Takaaki Hayashi, Hiroyuki Sasano, Satoshi Katagiri, Kazushige Tsunoda, Shuhei Kameya, Mitsuru Nakazawa, Takeshi Iwata, Hiroshi Tsuneoka. Heterozygous deletion of the OPA1 gene in patients with dominant optic atrophy. JAPANESE JOURNAL OF OPHTHALMOLOGY. 2017. 61. 5. 395-401
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Toshiyuki Yamada, Naoki Nanashima, Takeshi Shimizu, Yosuke Nakazawa, Mitsuru Nakazawa, Shigeki Tsuchida. Establishment of a recessive mutant small-eye rat with lens involution and retinal detachment associated with partial deletion and rearrangement of the Cryba1 gene. The Biochemical journal. 2015. 471. 2. 293-305
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MISC (66)：
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Pathogenesis of hereditary retinal diseases. 2015. 69. 12. 1602-1606
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Chiyoko Okamura, Hiroshi Kunikata, Toshiaki Abe, Mitsuru Nakazawa, Nobuo Fuse. Recurrence of uveal effusion in a case twenty-three years after initial sclerectomy. Japanese Journal of Clinical Ophthalmology. 2011. 65. 6. 895-900
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中澤満, 中澤徹. 眼科医にもわかる生理活性物質と眼疾患の基本 21 臨床編:各種眼疾患と生理活性物質とのかかわり 網膜色素変性. 臨床眼科. 2011. 65. 9
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Basic principles of cytokines, neurotrophic factors and other bioactive substances in ocular disease: Brain-derived neurotrophic factor. 2010. 64. 10. 1664-1667
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T Metoki, H Ohguro, Ohguro, I, K Mamiya, T Ito, M Nakazawa. Study of effects of antiglaucoma eye drops on N-methyl-D-aspartate-induced retinal damage. JAPANESE JOURNAL OF OPHTHALMOLOGY. 2005. 49. 6. 453-461
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Patents (3)：
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新規ペプチドおよびその医薬用途
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結膜下線維芽細胞増殖抑制剤および結膜下線維芽細胞増殖抑制方法
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経時変化記録画像による動画構造,動画作成用画像データ構造および経時変化記録画像による動画作成方法
Books (3)：
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A homozygous 1-base pair deletion(1147del A)in the arrestin gene in autosomal recessive retinitis pigmentosa
Retinal Degenerative Diseases and Experimental Therapy 1999
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Nonradioactive single strand conformation polymorphism(PCR-SSCP) : A simplified method applied to a molecular genetic screening of retinitis pigmentosa, In Retunal Degeneration
Plenum Publishing Corp. 1993
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Analysis of the rhodopsin gene in patients with retinitis pigmentosa Using polymerose chain reaction. In Current Aspects in Ophthalunology
Elsevier Science Publishers 1992
Education (2)：
- - 1980 Tohoku University Faculty of Medicine
- - 1980 Tohoku University Faculty of Medicine
Professional career (1)：
Work history (8)：
- 2021/04 - 現在 Hirosaki University
- 2006/04 - 2021/03 Hirosaki University, Graduate School of Medicine Department of Ophthalmology Professor
- 1998/04 - 2006/03 Hirosaki University, School of Medicine Department of Ophthalmology Professor
- 1995/07 - 1998/03 Tohoku University School of Medicine Department of Ophthalmology Associate Professor
- 1989/05 - 1995/06 Tohoku University School of Medicine Department of Ophthalmology Assistant Professor
- 1985/04 - 1989/04 Tohoku University School of Medicine Department of Ophthalmology Faculty member
- 1985/09 - 1988/08 University of Cincinnati College of Medicine Department of Ophthalmology Postdoctoral Research Assistant
- 1974/04 - 1980/03 Tohoku University School of Medicine
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Committee career (11)：
- 2022/01 - 現在 The Vitreoretina Society of Japan honorary member
- 2021/07 - 現在 The Japanese Society of Ocular Circulation honorary member
- 2021/04 - 現在 Japanese Society of Ophthalmology Honorary Member
- 1995/04 - 2022/12 The Japanese Society of Ophthalmic Diabetology board member
- 2013/04 - 2022/03 日本ロービジョン学会 評議員
- 2018/01 - 2022/01 The Vitreoretina Society of Japan board member
- 1999 - 2021/01 日本眼科学会 評議員
- 2016/01 - 2018/01 Japanese Society of Ophthalmology Counseler
- 2004/07 - 2016/07 The Japanese Society of Ocular Circulation board member
- 2008/04 - 2012/03 日本網膜硝子体学会 監事
- 2001 - 2008 日本網膜硝子体学会 理事
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Awards (2)：
- 1996 - 日本眼科学会学術奨励賞
- 1996 - 第1回 Rohto Award
Association Membership(s) (6)：
日本糖尿病眼学会
, 日本眼循環学会
, 日本ロービジョン学会
, 日本臨床視覚電気生理学会
, 日本網膜硝子体学会
, 日本眼科学会
