Tooyama Ikuo

2017 - 2021 Simultaneous analysis of Aß oligomers, Aß fibrils and phosphrylated tau protein using fluroine-MRI

2015 - 2019 Development novel probes for fluorine MRI to detect neurodegenerative diseases

2015 - 2018 Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in COX6A1

2015 - 2018 Subclinical atherosclerosis and brain atrophy in the general Japanese women

2014 - 2017 Development of novel diagnostic and therapeutic methods on Alzheimer's disease by targeting amyloid oligomers

2014 - 2016 Study of a highly sensitive C-13 MR glucose metobolite mapping with the brain of an Altzheimer model mouse

2014 - 2016 ケミカルシフトの違いを利用したフッ素MR画像による複数の脳内異常蛋白の同時解析

2014 - 2016 Determinations of nasal biomarkers for dementia and development of a novel diagnostic method for Alzheimer's disease using nasal samples.

2013 - 2016 Development of the method of measurement of amyloid-beta in nasal samples for diagnosis of Alzheimer's Disease

2012 - 2015 Central sensitization mechanism depends on microglia participates in Lower Urinary Tract Symption

2012 - 2015 General transcription factor TAF1 is involved in transcriptional impairment and neurodegeneration

2011 - 2015 Comparison Western Japan with Eastern Japan about the cause of asymptomatic cerebrovascular disorders and hippocampal atrophy in general Japanese men

2012 - 2014 フッ素MR画像法と光画像法によるアミロイドオリゴマーのin vivo病態解析

2010 - 2014 Development of amyloid imaging using fluorine-MRI

2011 - 2012 Development of hemodiagnostic methods for Alzheimer's disease using curcuimin derivatives

2009 - 2011 ES細胞におけるナトリウム利尿ペプチドの役割の解明

2007 - 2009 Research on production of a primate model for schizophrenia and development of transplant therapy by neural stem cell grafts

2007 - 2009 Development of diagnostic methods for Parkinson disease using high fieled magnetic resonance imaging

2004 - 2008 Non-invasive MRI tracking of labeled stem cells and its application to regenerative medicine

2006 - 2007 ES細胞をししたアルツハイマー病モデルサルの作成

2004 - 2006 Novel cholineacetyltransferase variants (pChAT) in the brain of human and monkey

2003 - 2005 A study for regulation of inner ear fluid using molecular biology metod

2001 - 2002 Study on novel cholinergic pathways in the brain of patients with Alzheimer's disease

2000 - 2001 Expression of a splice variant of choline acetyltransferase in magnocellular neurons of the tuberomammillary nucleus of rats

1999 - 2001 Localization of peptides that regulate inner ear fluid in the rat

1998 - 2000 Studies on Neuronal mRNA Splicing

1998 - 2000 神経細胞の核内転写因子の人工制御による脳機構の解明

1998 - 1999 Study on the central nervous system of rat with systemic inflammatory response syndrome (SIRS)

1997 - 1999 生体内増幅アンチセンスRNAを用いる脳機能解析法の開発

1996 - 1998 Expression of fluid regulation peptides in the inner ear.

1995 - 1997 Development of in situ PCR method and its application to histochemistry

1995 - 1996 Localization and function of acidic fibroblast growth factor in adrenal gland

1994 - 1995 "Expression of c-fos protein in rat brain after occlusion of superior mesenteric artery (immunohistochemical investigation)"

1994 - 1995 Joint study on deltorphines in the mammalian brain

1991 - 1992 Non-radioactive in situ hybridization histochemistry using chemically defined boitin-labeled probes.

1989 - 1991 Molecular neurobiological study on the deterioration of specific genes for dementia of Alzheimer type

1990 - 1990 ラット脳およびヒト剖検脳における酸性線維芽細胞成長因子の免疫組織化学的研究

1989 - 1990 Taurine Immunohistochemistry in the Liver

1989 - 1989 脳内セロトニン神経系の機能形態学的研究

1988 - 1989 IMMUNOHISTOCHEMICAL STUDY OF THE CENTRAL CHOLINERGIC SYSTEM BY USING ANTIBODY TO ACETYLCHOLINE.

1988 - 1988 シナプス形成に関するモノアミン神経の機能形態学的研究

アルツハイマー病の診断・治療法に関する研究

認知症の神経病理学的研究

コリン神経の分子科学

Study on Alzheimer

Neuropathological study on dementia

Molecular Neurosuence in Cholinergic neuron