Ishikawa Fuyuki

イシカワフユキ | Ishikawa Fuyuki

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.lif.kyoto-u.ac.jp/labs/fish/index.html

Research field (1)： Molecular biology

Research keywords (9)：ストレス反応 , 発がん , 老化 , テロメア , 染色体 , carcinogenesis , aging , telomere , chromosome

Research theme for competitive and other funds (77)：

2019 - 2023 微小環境変動に対する細胞応答に着目した治癒をめざした抗腫瘍療法
2014 - 2018 Suppression of telomerase-independent telomere maintenance mechanism in cancer cells
2017 - 2018 テロメア反応トランスアクションの研究 (平成29年度分)
2014 - 2018 ステムセルエイジングのエピジェネティクスとストレスシグナル
2016 - 2017 テロメア反応トランスアクションの研究 (平成28年度分)

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Papers (188)：

Yukiko Kojima, Saki Fujieda, Liya Zhou, Masahiro Takikawa, Kouji Kuramochi, Toshiki Furuya, Ayaka Mizumoto, Noritaka Kagaya, Teppei Kawahara, Kazuo Shin-ya, et al. Cytochrome P450 2J2 is required for the natural compound austocystin D to elicit cancer cell toxicity. Cancer Science. 2024
Yoshikazu Nagagaki, Yuji Kozakura, Theventhiran Mahandaran, Yukiko Fumoto, Ryuichiro Nakato, Katsuhiko Shirahige, Fuyuki Ishikawa. Histone H3.3 chaperone HIRA renders stress-responsive genes poised for prospective lethal stresses in acquired tolerance. Genes to Cells. 2024
Diana Romero-Zamora, Samuel Rogers, Ronnie Ren Jie Low, Andrew B. Robinson, Scott G. Page, Blake J. E. Lane, Noa Lamm, Fuyuki Ishikawa, Makoto T. Hayashi, Anthony J. Cesare. A CPC-shelterin-BTR axis regulates mitotic telomere deprotection. 2024
Ayaka Mizumoto, Yuta Yokoyama, Tomoichiro Miyoshi, Masahiro Takikawa, Fuyuki Ishikawa, Mahito Sadaie. DHX36 maintains genomic integrity by unwinding G-quadruplexes. Genes to Cells. 2023. (Epub)
Tomohiko Hara, Hidenori Nakaoka, Tomoicihiro Miyoshi, Fuyuki Ishikawa. The CST complex facilitates cell survival under oxidative genotoxic stress. PLOS ONE. 2023. 18. 8. e0289304

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MISC (95)：

滝川雅大, 滝川雅大, 岡部篤史, 金田篤志, 石川冬木, 定家真人, 大木理恵子. A novel extrinsic apoptosis pathway regulated via the p53-p53PAD7-Hippo-YAP/TAZ axis. 日本癌学会学術総会抄録集(Web). 2023. 82nd
山本唯央, 山本唯央, 中岡秀憲, 滝川雅大, 田代三喜, 加納純子, 三好知一郎, 石川冬木. Stn1, telomeric protein, maintains the stability of repetitive sequences at rDNA and subtelomeres in fission yeast. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
西森奎, 西森奎, AHMAD Luqman-Fatah, AHMAD Luqman-Fatah, 渡邉祐三, 石川冬木, 石川冬木, 三好知一郎, 三好知一郎. The interferon stimulated gene product HERC5 inhibits human LINE-1 retrotransposition. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
小島有紀子, 滝川雅大, 新家一男, 旦慎吾, 石川冬木, 定家真人. Molecular mechanisms behind the cytotoxicity of the natural product AusD in osteosarcoma cells. 日本癌学会学術総会抄録集(Web). 2022. 81st
滝川雅大, 滝川雅大, 岡部篤史, 金田篤志, 石川冬木, 定家真人, 大木理恵子. Secreting protein p53PAD7 inhibits cell proliferation via the Hippo signaling pathway. 日本癌学会学術総会抄録集(Web). 2020. 79th

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Patents (10)：

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Books (35)：

Aging mechanisms : longevity, metabolism, and brain aging
Springer 2022 ISBN:9784431557623
生物の寿命延長 : 老化・長寿命の基盤研究最前線
エヌ・ティー・エス 2022 ISBN:9784860437732
Genomes (4th ed.)
2018
京大発!フロンティア生命科学
講談社 2018
“CST Complex and Telomere Maintenance” in DNA Replication, Recombination, and Repair.
Springer 2016

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Lectures and oral presentations (236)：

腫瘍細胞の生体内環境適応
(2021)
Elucidating the biological role of telomeres.
(2021)
Understanding how cells respond to ever-changing "real world"
(2021)
医療現場のデジタル改革:コロナ禍で分かったこと
(2021)
How to cure cancer
(NTU-KU-UT mini virtual symposium on Cancer Biology & Medicine 2020)

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Works (2)：

テロメアが老化にかかわる機序の研究
2002 -
Roles of telomeres in Aging processes
2002 -

Professional career (1)：

MD. Ph.D (The University of Tokyo)

Work history (15)：

2022/04 - 現在 Kyoto University Research Administration Center (KURA) Director
2022/03 - 現在 Kyoto University Vice President
2002 - 2023/03 Professor, Graduate School of Biostudies, Kyoto University
1999 - 2002 Professor, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology
1998 - 1999 Professor, Department of Life Science, Tokyo Institute of Technology

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Committee career (2)：

2017/10 - 2020/09 日本学術会議会員・第二部長
2014/10 - 2017/09 日本学術会議会員・第二部幹事

Awards (7)：

2021/09 - The Genetics Society of Japan Kihara Prize Elucidating the biological role of telomeres
2009 - 日産科学賞
2009 - Nissan Science Prize
2006 - 日本人類遺伝学会賞
2006 - The Japan Society of Human Genetics Prize

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Association Membership(s) (20)：

The Ammerican Society For Biochemistry and Molecular Biology , American Association for Cancer Research , 日本RNA学会 , がん分子標的治療学会 , 日本人類遺伝学会 , 日本遺伝学会 , 日本生化学会 , 日本細胞生物学会 , 日本分子生物学会 , 日本癌学会 , The Ammerican Society For Biochemistry and Molecular Biology , American Association for Cancer Research , The RNA Society of Japan , The Japanese Association for Molecular Target Therapy of Cancer , The Japan Society of Human Genentics , The Genetics Society of Japan , The Japanese Biochemical Society , Japan Society for Cell Biology , The Molecular Biology Society of Japan , Japanese Cancer Association

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