Mitoh Yoshihiro

ミトウヨシヒロ | Mitoh Yoshihiro

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Oral medicine

Research keywords (2)：口腔生理学 , Oral Physiology

Research theme for competitive and other funds (27)：

2024 - 2027 Protection of the salivary gland during radiotherapy for head and neck cancer
2022 - 2025 口腔機能低下症に迷走神経刺激は有効か:脳腸連関によるニューロモジュレーション解析
2021 - 2025 The raison d'etre of classical synapses in taste buds
2021 - 2024 おいしく食べるための唾液、その中枢神経機構の解明
2018 - 2021 A study on brain mechanisms in which mental activity influences salivary secretion

2017 - 2020 精神活動により影響される唾液分泌に関する研究

2015 - 2018 Study for regulatory mechanism of feeding-related phenomena by GLP-1

2014 - 2017 Approach to Educate HACCP in Schools of Medicine, Dentistry and Pharmacy

2014 - 2017 A study on mechanisms regulating salivary secretion during feeding

2014 - 2017 Neural mechanisms of salivary secretion related to oral senses and mastication.

2013 - 2016 A study for role of the feeding center in submandibular and sublingual salivary secretion

2011 - 2013 Analysis of neural network for maintenance salivary secretion

2010 - 2012 Central orexin-A inhibits reflex swallowing via caudal brainstem

2009 - 2011 Reguraltory mechanisms of neuronal activity in the superior salivatory nucleus by feeding-related peptides.

2007 - 2008 Central ghrelin inhibits reflex swallowing and induces gastric relaxation of the rats

2007 - 2008 Study on the glutamatergic inputs from the forebrain and brainstem to the neurons innervating submandibular salivary glands

2006 - 2007 唾液核に対する興奮性入力の解析-グルタミン酸バイオセンサーによる行動学的測定法一

2005 - 2006 Analysis of the functional and biological roles of the hyperpolarization-activated cation current in the central nervous system,

2005 - 2006 The study for functional correlation between palatability and gastric motility induced by appetite-enhancing peptides.

2005 - 2006 Electrophysiological study on development of inhibitory synaptic transmission in central neurons involved in oral function.

2003 - 2004 Mechanisms Involving in the Inhibition of Nitric Oxide-Mediated Lower Esophageal Sphincter Relaxation Induced by Volatile Anesthetics in Rabbits.

2003 - 2004 Analysis of the functional role of the hyperpolarization-activated cation cunert within the centaral nervous system.

2002 - 2003 Electrophysiological analysis of impulse formation in the salivary secretory neurons

1999 - 2000 Electrophysiological analysis of brainstem neurons subserving autonomic and motor oral functions

1997 - 1998 Electrophysiological analysis of the lateral reticular formation controlling orofacial autonomic and motor functions

1996 - 1996 咽頭部および喉頭部の化学受容:Clイオンチャネルの関与

1993 - 1994 Electrophysiological and microdialytic analysis on responses of dopaminergic and noradrenergic neurons in the medulla ablongata (A2aea)

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Papers (55)：

Aiko Hyodo, Ayaka Mikami, Kengo Horie, Yoshihiro Mitoh, Yuzo Ninomiya, Seiji Iida, Ryusuke Yoshida. Salivary buffering capacity is correlated with umami but not sour taste sensitivity in healthy adult Japanese subjects. Archives of Oral Biology. 2024. 165. 106013-106013
Ayaka Mikami, Hai Huang, Aiko Hyodo, Kengo Horie, Keiko Yasumatsu, Yuzo Ninomiya, Yoshihiro Mitoh, Seiji Iida, Ryusuke Yoshida. The role of GABA in modulation of taste signaling within the taste bud. Pflügers Archiv - European Journal of Physiology. 2024
Tomiko Nishitani, Yoshihiro Mitoh, Takehiro Yajima, Daisuke Tachiya, Tomohiro Hoshika, Tomohiro Fukunaga, Yoshihiro Nishitani, Ryusuke Yoshida, Itaru Mizoguchi, Hiroyuki Ichikawa, et al. Distribution of alpha-synuclein in rat salivary glands. The Anatomical Record. 2024
Mitsuhito Takamori, Yoshihiro Mitoh, Kengo Horie, Masahiko Egusa, Takuya Miyawaki, Ryusuke Yoshida. Sugar signals from oral glucose transporters elicit cephalic-phase insulin release in mice. The Journal of Physiological Sciences. 2023. 73. 1
Yamase Yuko, Huang Hai, Mitoh Yoshihiro, Egusa Masahiko, Miyawaki Takuya, Yoshida Ryusuke. Taste Responses and Ingestive Behaviors to Ingredients of Fermented Milk in Mice. Foods. 2023. 12. 6. 1150

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MISC (24)：

Yoshihiro Mitoh, Tadasu Sato, Masako Fujita, Motoi Kobashi, Hiroyuki Ichikawa, Ryusuke Yoshida. Effects of appetite-boosting peptides on parasympathetic preganglionic neurons innervating the submandibular and sublingual salivary glands in rats. The Japanese Journal of Taste and Smell Research. 2019. S55-S58
小橋基, 島谷祐一, 美藤純弘, 藤田雅子, 松尾龍二. 嚥下反射に及ぼすオレキシンAとグルカゴン様ペプチド1の相互作用. 日本味と匂学会誌. 2017. 24. 3
美藤純弘, 藤田雅子, 小橋基, 松尾龍二. 口腔の生理から考える臨床像(18)前脳による唾液分泌の調節. 日本歯科評論. 2016. 76. 6. 145-150
MATSUO Ryuji, MITOH Yoshihiro, MATSUSHIMA Ayumi. Mental stress and descending neural control to the superior salivatory nucleus. Folia Pharmacologica Japonica. 2013. 141. 6. 306-309
Ueda Hirotaka, Mitoh Yoshihiro, Ichikawa Hiroyuki, Kobashi Motoi, Yamashiro Takashi, Matsuo Ryuji. CEVIMELINE ENHANCES THE EXCITABILITY IN THE RAT SUPERIOR SALIVATORY NUCLEUS NEURONS. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2009. 59. 142

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Books (10)：

平成30-令和2年度科学研究費補助金(基盤研究C)成果報告書
日本学術振興会 2021
A study for role of the feeding center in submandibular and sublingual salivary secretion
Japan Society for the Promotion of Science 2016
平成21-23年度科学研究費補助金(基盤研究C)成果報告書
日本学術振興会 2011
平成19-20年度科学研究費補助金(基盤研究C)成果報告書
日本学術振興会 2009
生物学に関する試験研究論叢(第二十二集)
財団法人両備てい園記念財団 2007

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Lectures and oral presentations (146)：

Enantiomers of organic acids are identified by the preference taste receptors Tas1R2/Tas1R3 or Tas1R1/Tas1R3
(The 20th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception 2023)
Ccn3 expression in the murine taste bud does not confer essential roles in taste perception
(The 20th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception 2023)
SNAP-25 contributes to the maintenance of Type III taste receptor cells
(The 20th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception 2023)
Analysis of mice lacking synapses in taste buds
(The 65th Annual Meeting of Japanese Association for Oral Biology 2023)
Effects of dopamine on the superior salivatory nucleus neurons innervating the salivary glands in rats
(The 65th Annual Meeting of Japanese Association for Oral Biology 2023)

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Education (2)：

- 1991 Okayama University
- 1988 Kobe Gakuin University The Faculty of Pharmaceutical Sciences

Professional career (2)：

Doctor of Philosophy (Okayama University)
Master of Pharmaceutical Science (Okayama University)

Work history (2)：

2004 - - 岡山大学医歯薬学総合研究科助教
2004 - - Assistant Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University

Committee career (8)：

2019 - 現在日本栄養・食糧学会会員
1997 - 現在岡山歯学会会員
1994 - 現在歯科基礎医学会会員
1994 - 現在日本味と匂学会評議員
1993 - 現在日本生理学会評議員

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Association Membership(s) (9)：

日本薬学会 , 岡山歯学会 , 歯科基礎医学会 , 日本味と匂学会 , 日本生理学会 , International Association for Dental Research , Society for Neuroscience , International Association for Dental Research , Society for Neuroscience

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