Kakugo Akira

カクゴアキラ | Kakugo Akira

Affiliation and department：
Job title： Professor
Homepage URL (1)： https://chem.scphys.kyoto-u.ac.jp/

Research field (3)： Nanobioscience , Nanomaterials , Bio-, chemical, and soft-matter physics

Research keywords (8)： Active matter , Collective motion , Molecular Robotics , Self organization , 力学刺激 , 生体分子モーター , 分子コンピューティング , DNAナノ構造

Research theme for competitive and other funds (27)：

2020 - 2025 AIとVRを活用した分子ロボット共創環境の研究開発
2021 - 2024 Structural damage to axons resulting from repetitive mechanical motion
2021 - 2024 Experimental and theoretical study of the cytoskeleton "microtubules" as mechanotransducers.
2021 - 2024 Molecular swarm robotics: Verifying working ability of molecular robots and their implementation in social contexts
2018 - 2023 Emergence of autonomous functions through hierarchical integration of molecular engines

2018 - 2023 Emergence of autonomous functions through hierarchical integration of molecular engines

2018 - 2021 Development of biomolecular motor based autonomous molecular-robots and its potential application

2018 - 2021 Rational design of a novel power system from biomolecular motor

2018 - 2021 生体分子機械による革新的動力システムの合理設計

2017 - 2020 Gene profiling for pressure ulcer

2016 - 2020 生体分子ロボット/分子人工筋肉の研究開発

2017 - 2019 Creation of periodic pattern of metal nanoparticles on helical lattice of internal skeleton of microtubules

2015 - 2018 Sensing Surface Mechanical Deformation Using Active Probes Driven by Motor Proteins

2015 - 2018 Development of a fundamental concept for manipulating biomolecular motors

2016 - 2018 Sensing Surface Mechanical Deformation Using Active Probes Driven by Motor. Proteins(Fostering Joint International Research)

2016 - 2018 ソフトマテリアル表面を探査する自律走査型マルチアクティブプローブ法の開発(国際共同研究強化)

2012 - 2017 Research and Development of Amoeba-type Molecular Robots

2015 - 2017 Development of a method to control collective motion of self-propelled bio-molecular motor system

2015 - 2017 Development of autonomous active probes for studying properties of soft material surface

2012 - 2017 Development and integration of element technology for materializing amoeboid type robot

2013 - 2015 擬似植物細胞モデルにおける微小管の力学応答特性

2013 - 2014 Mechanical response of microtubules in a pseudo plant cell

2011 - 2014 Study on the roles of internal and external factors in active self-organization of biomolecular motor

2008 - 2011 Creation of an ATP fueled soft-biomachine with hierarchical structure

2006 - 2010 Material Innovation for the Age of Life Science-Creation of Soft and Wet Materials

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Papers (183)：

Soei Watari, Hiroshi Inaba, Qianru H Lv, Muneyoshi Ichikawa, Takashi Iwasaki, Bingxun Wang, Hisashi Tadakuma, Akira Kakugo, Kazunori Matsuura. Optical Control of Microtubule Accumulation and Dispersion by Tau-Derived Peptide-Fused Photo-Responsive Protein. 2024
Mousumi Akter, Arif Md. Rashedul Kabir, Jakia Jannat Keya, Kazuki Sada, Hiroyuki Asanuma, Akira Kakugo. Localized Control of the Swarming of Kinesin-Driven Microtubules Using Light. ACS Omega. 2024
Syeda Rubaiya Nasrin, Takefumi Yamashita, Mitsunori Ikeguchi, Takayuki Torisawa, Kazuhiro Oiwa, Kazuki Sada, Akira Kakugo. Tensile Stress on Microtubules Facilitates Dynein-Driven Cargo Transport. Nano letters. 2024
Allegra Coppini, Alessandro Falconieri, Oz Mualem, Syeda Rubaiya Nasrin, Marine Roudon, Gadiel Saper, Henry Hess, Akira Kakugo, Vittoria Raffa, Orit Shefi. Can repetitive mechanical motion cause structural damage to axons?. Frontiers in Molecular Neuroscience. 2024. 17
Ibuki Kawamata, Kohei Nishiyama, Daiki Matsumoto, Shosei Ichiseki, Jakia J. Keya, Kohei Okuyama, Masatoshi Ichikawa, Arif Md. Rashedul Kabir, Yusuke Sato, Daisuke Inoue, et al. Autonomous assembly and disassembly of gliding molecular robots regulated by a DNA-based molecular controller. Science Advances. 2024. 10. 22

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MISC (87)：

Arif Md. Rashedul Kabir, Akira Kakugo. A new approach to explore the mechanoresponsiveness of microtubules and its application in studying dynamic soft interfaces. POLYMER JOURNAL. 2021. 53. 2. 299-308
末岐優里菜, 稲葉央, 岩崎崇, KABIR Arif Md. Rashedul, 角五彰, 佐田和己, 松浦和則. Stabilization of microtubules by encapsulation of tetrameric fluorescent proteins using Tau-derived peptides. 日本化学会春季年会講演予稿集(Web). 2021. 101st
Kabir Arif Md. Rashedul, Kakugo Akira, Kakugo Akira. A new approach to explore the mechanoresponsiveness of microtubules and its application in studying dynamic soft interfaces. Polymer Journal. 2021. 53. 2
Kabir Arif Md. Rashedul, Sada Kazuki, Kakugo Akira. Controlling the length of self-assembled microtubes through mechanical stress-induced scission. Chemical Communications. 2021. 57. 4
松田健人, KABIR Arif Md.Rashedul, 佐田和己, 佐田和己, 葛谷明紀, 角五彰, 角五彰. 生体分子モーターとDNAオリガミによる分子人工筋肉の開発. Bio Industry. 2020. 37. 2

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Books (21)：

Handbook of Unconventional Computing: Theory / Implementations (Wspc Book Series in Unconventional Computing)
2021 ISBN:9811235031
次世代のポリマー・高分子開発、新しい用途展開と将来展望
技術情報協会 2019
刺激応答性高分子ハンドブック
(株)NTS出版 2019
分子ロボティクス概論
情報計算化学生物学会(CBI出版) 2018
ソフトアクチュエータの材料・構成・応用技術
(株)S&T出版 2016

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Lectures and oral presentations (48)：

アクティブマターを活用した分子ロボット開発
(計測自動制御学会SI部門ソフトマテリアル応用部会研究会 2016)
Mechanical deformation induced modulation of biochemical functions of microtubule
(第6回ソフトマター研究会 2016)
アクティブバイオマターを活用した新たな研究展開
(高分子学会バイオ・高分子研究会 2016)
生体分子モーターを用いた動的自己組織化に関する研究
(高分子学会討論会 2016)
バイオ系のアクティブマター
(ソフトマター若手勉強会 - ゆらぎと構造の協奏 2016)

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Education (2)：

2000 - 2003 Hokkaido University Graduate School of Science Doctor's Course
- 1998 Hokkaido University Faculty of Fisheries

Professional career (2)：

M.S. (Hokkaido University)
Ph.D. (Hokkaido University)

Work history (14)：

2022/12 - 現在 Kyoto University Graduate School of Science, Department of Physics and Astronomy Professor
2024/04 - 2024/09 Osaka University Graduate School of Science Lecturer
2011/05 - 2022/11 Hokkaido University Graduate School of Science Associate Professor
2019/10 - 2020/03 Fukuoka University Faculty of Science Lecturer
2019/09 - 2020/03 Osaka University Graduate School of Engineering Lecturer

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Awards (4)：

2021/04 - International Human Frontier Science Program Organization HFSP Awards 2021 : Research Grants-Program Structural damage to axons resulting from repetitive mechanical motion
2019/09 - TECH PLANTER The 6th Tech Planter : Ebara Corporation Award Technology to convert and amplify bioenergy into electrical energy
2016/09 - The Society of Polymer science, Japan SPSJ Science Award Study on Dynamic Self-organization Using Bio-molecular Motors
2014/04 - The Ministry of Education, Culture, Sports, Science & Technology (MEXT) Japan prize for young scientists 2011 Study on ATP fueled Soft-actuator constructed from Bio-molecular Motors

Association Membership(s) (9)：

The Society of Polymer Science, Japan , American Chemical Society , The Cellulose Society of Japan , Division of Colloid and Surface Chemistry , The Material Research Society of Japan , Molecular Robotics Research Group , Biophysical Society of Japan , The Biophysical Society of Japan , Chemical Society of Japan

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