Rchr
J-GLOBAL ID：200901055328608810   Update date: Sep. 29, 2025

Ishihama Yasushi

イシハマ ヤスシ | Ishihama Yasushi
Affiliation and department：
Kyoto University Graduate School of Pharmaceutical Sciences

About Kyoto University Graduate School of Pharmaceutical Sciences


Job title： Professor
Research field  (1)： Pharmaceuticals - analytical and physicochemistry
Research keywords  (5)： Proteomics ,  Post-Translational Modification ,  Mass Spectrometry ,  Separation Science ,  HPLC
Research theme for competitive and other funds  (38)：
  • 2023 - 2028 Large-scale measurement techniques for protein lifetime and principles of lifetime control
  • 2023 - 2028 Shin-biology regulated by protein lifetime
  • 2024 - 2027 精密メタプロテオーム解析を実現する高度情報科学基盤の構築
  • 2022 - 2026 Pathophysiological study of NMD-targeted transcripts by trans-omics analysis
  • 2022 - 2026 Pathophysiological study of NMD-targeted transcripts by trans-omics analysis
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Papers (304)：
  • Pei-Shan Wu, Ting-An Chen, Bo-Yu Chen, Yasushi Ishihama, Miao-Hsia Lin. A Methanolic Urea-enhanced Protein Extraction Enabling the Largest Bacterial Phosphorylation Resource. Molecular & cellular proteomics : MCP. 2025. 101019-101019
  • Tsuyoshi Tabata, Akiyasu C Yoshizawa, Kosuke Ogata, Chih-Hsiang Chang, Norie Araki, Naoyuki Sugiyama, Yasushi Ishihama. UniScore, a unified and universal measure for peptide identification by multiple search engines. Molecular & cellular proteomics : MCP. 2025. 101010-101010
  • Kankichi Kako, Eisuke Kanao, Yasushi Ishihama, Sayaka K-Yamada, Takuya Kubo. Selective fluorescence detection of proteins using molecularly imprinted hydrogels with aggregation-induced emission. Journal of materials chemistry. B. 2025. 13. 21. 6086-6092
  • Nobuaki Takemori, Philipp T Kaulich, Jan Hahn, Hartmut Schlüter, Naoyuki Sugiyama, Kazuya Tsumagari, Yasushi Ishihama, Sabine Fuchs, Mio Iwasaki, Franz-Josef Müller, et al. Meeting Report: The Japanese-German Symposium on the "Advancement and Application of Proteoform-Centric Proteomics" (Kyoto, Japan, 2024). Proteomics. 2025. e202400394
  • Koshin Akamatsu, Eisuke Kanao, Ayana Tomioka, Yasushi Ishihama. Two-Step Peptide Solubilization Increases Coverage in High-Sensitivity NanoHILIC/MS/MS-Based Proteomics. Analytical chemistry. 2025. 97. 19. 10227-10235
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MISC (627)：
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Patents (51)：
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Books (3)：
  • 臨床プロテオミクス-バイオマーカー探索から個別化医療へ
    金原出版 2012
  • 疾患克服をめざしたケミカルバイオロジー
    羊土社 2012
  • 「特集」プロテオミクスが解き明かす情報伝達ネットワーク : タンパク質リン酸化の全体像の解析から病態機構の理解分子標的薬評価の応用まで
    羊土社 2009 ISBN:9784758100526
Lectures and oral presentations  (84)：
  • Peptide Chromatographic Approaches for Illuminating Human Proteome
    (18th KHUPO Annual International Proteomics Conference 2018)
  • ショットガンプロテオミクスにおける計測と情報の新展開
    (第15回北里疾患プロテオーム研究会 2018)
  • Proteomic Data Integration and Sharing by jPOST Repository/Database
    (International Life Science Integration Workshop 2018)
  • Kinome activity profiling based on large-scale kinase-substrate relationships
    (AOMSC 2017 2017)
  • プロテオミクスを用いて暗黒キノーム世界を照らす
    (キャピラリー電気泳動シンポジウム講演要旨集 2017)
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Works (5)：
  • 理研・植物科学研究センターでの招待講演「進化するプロテオミクス質量分析」
    2006 -
  • 2006年サーモエレクトロンユーザーズフォーラムでの招待講演「プロテオミクス質量分析の挑戦」
    2006 -
  • 第9回ヒューマンサイエンス総合研究ワークショップでの招待講演「定量的プロテオミクスの展開」
    2006 -
  • 第222回東北大学薬学研究科セミナーでの招待講演「定量的プロテオミクスの展開」
    2006 -
  • 第54回質量分析総合討論会、企業セミナー(日本ダイオネクス主催)での招待講演「定量的組織プロテオーム解析法の開発とその応用」
    2006 -
Education (2)：
  • - 1992 Kyoto University
  • - 1990 Kyoto University Faculty of Engineering School of Industrial Chemistry
Professional career (1)：
  • Ph. D. (Kyoto University)
Work history (5)：
  • 2010/10 - 現在 Kyoto University Graduate School of Pharmaceutical Sciences
  • 2006/04 - 2010/09 慶應義塾大学大学院政策・メディア研究科特別研究助教授
  • 2006/10 - 2010/03 (独)科学技術振興機構さきがけ研究員(兼任)
  • 2004/04 - 2006/03 慶應義塾大学大学院政策・メディア研究科特別研究助教授(非常勤・兼任)
  • 2001/07 - 2003/07 南デンマーク大学生化学分子生物学科 客員研究員
Committee career (20)：
  • 2025/06 - 現在 Asia-Oceania Mass Spectrometry Conference International Committee Chair
  • 2025/02 - 現在 Division of Physical Sciences, the Pharmaceutical Society of Japan President
  • 2023/05 - 現在 Mass Spectrometry Society of Japan President
  • 2023/01 - 現在 Asia Oceania Human Proteome Organisation (AOHUPO) Vice President
  • 2022/11 - 現在 Journal of Pharmaceutical and Biomedical Analysis Open Journal of Pharmaceutical and Biomedical Analysis Open, Editorial Board
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Awards (8)：
  • 2022/07 - The Japanese Biochemical Society Journal of Biochemistry Award Quantitative nascent proteome profiling by dual-pulse labelling with O-propargyl-puromycin and stable isotope-labelled amino acids
  • 2022/06 - The Mass Spectrometry Society of Japan MSSJ AWARD for Excellent Paper Effect of Phosphorylation on the Collision Cross Sections of Peptide Ions in Ion Mobility Spectrometry
  • 2021/09 - The Japan Society for Analytical Chemistry JSAC Award
  • 2020/11 - The Terabe Shigeru Prize
  • 2018/11 - The Society for Chromatographic Sciences SCS Award
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Association Membership(s) (10)：
THE JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY ,  American Society for Biochemistry and Molecular Biology ,  Human Proteome Organization ,  American Society for Mass Spectrometry ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  Society for Chromatographic Sciences ,  THE MASS SPECTROMETRY SOCIETY OF JAPAN ,  Japanese Proteomics Society
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