Okamura Tadashi

2017 - 2020 Analysis of the mechanism of autoimmune diseases

2017 - 2020 Identification of a novel drug target for rare disease using murine model of cystinosis

2016 - 2019 Molecular basis for T cell repertoire formation in thymic microenvironment

2016 - 2019 Novel murine model of congenital diabetes

2016 - 2018 Molecular mechanism of lysosome-dependent allergic inflammation

2014 - 2018 Mechanisms of increased glucose-stimulated insulin secretion during pregnancy

2014 - 2017 A novel regulatory mechanism of autoimmune disease pathogenesis by SLC15A4

2014 - 2017 Elucidation of mechanisms of metabolic disorder-associated genes by the integration of genomic and non-genomic approaches

2014 - 2017 Genetic linkage analysis and identification of obesity-related gene in LEA rat

2014 - 2016 Establishment of murine model of autoimmune diseases

2012 - 2015 Development of animal model for the blood sugar regulation by glycosphingolipids and study on the molecular pathogenesis of inflammation in adipose tissue

2010 - 2015 Integrated redearch for HLA disease and evolution

2011 - 2013 Deletion of CDKAL1 affects first-phase glucose stimulated insulin exocytosis

2011 - 2013 Establishment of a novel rat model for cystinosis

2010 - 2012 Genetic and immunological analysis for HLA-DP5 and HLA-DR53 related diseases.

2010 - 2011 Elucidation of molecular mechanisms and in vivo functions of GRIN3 for dopamine D2 receptor

2009 - 2011 A study on regulatory genomic regions and functional RNAs in pancreatic β-cells

2008 - 2009 Functional analysis of GRIN family in the central nervous system

2005 - 2009 Immunogenetic Analysis of Autoimmune Thyroid Diseases

2006 - 2007 The analyses of role of copper on the diabetes in the animal model with diabetes and copper metabolism deficiency

2005 - 2006 網羅的遺伝子発現解析とQTL解析を組合せた新規2型糖尿病ラットの糖尿病遺伝子探索

2003 - 2004 遺伝子発現パターン解析によるプリオン病の早期診断法の探索

2000 - 2002 Establishment of support network system for the technology of gene alternated mice production and embryonic manipulation by closer cooperation with academic and industrial fields

1999 - 2001 Establishment of model mouse susceptible to human prion; Visualization of the molecular interaction of prion protein in vivo

A gain-of-function mutation of the major intrinsic protein gene causes bilateral ccnginital cataracts in mice.

Analysis of ceramide glucosyltransferase transgenic mice/