Research field (6):
Tumor biology
, Pharmaceuticals - chemistry and drug development
, Food sciences
, Nephrology
, Physiology
, Pharmaceuticals - health and biochemistry
2013 - 2017 Elucidation of Na+ recycling mechanisms induced by Na-dependent nutrient absorption in the small intestine
2013 - 2016 Clarification of molecular and physiological properties of the acid-preventing barrier in gastric parietal cells
2011 - 2013 Clarification of novel regulatory mechanism of intercellular junction in renal tubules
2008 - 2010 A novel molecular complex formed by paracellin-1 involved in the regulation of magnesium reabsorption
2005 - 2007 パラセリン-1によるタイトジャンクション新規マグネシウム再吸収機構の解明
2000 - 2001 マグネシウム輸送体の調節機構と高血圧発症に対する影響
1998 - 2000 The recognition and transport mechanism of ions in the proton pump and its intracellular transport
1998 - 1998 化学療法剤による下痢発症機構と下痢抑制剤併用療法の基礎
1998 - 1998 生体防御塩素イオンチャネル
1997 - 1997 化学療法剤による下痢発症機構と下痢抑制剤併用療法の基礎
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Papers (188):
Yuko Mizukami, Ayaka Ito, Shotaro Hashimoto, Tomoka Ando, Yoshinobu Ishikawa, Hiroaki Eguchi, Yuta Yoshino, Toshiyuki Matsunaga, Akira Ikari. Downregulation of chemoresistance by claudin-14 silencing in human colorectal cancer cells. Archives of biochemistry and biophysics. 2024. 758. 110075-110075
Riho Kimura, Shotaro Hashimoto, Hiroaki Eguchi, Yoshifumi Morikawa, Koichi Suenami, Yuta Yoshino, Toshiyuki Matsunaga, Satoshi Endo, Akira Ikari. Enhancement of chemoresistance by claudin-1-mediated formation of amino acid barriers in human lung adenocarcinoma A549 cells. Archives of biochemistry and biophysics. 2024. 759. 110106-110106
Yuta Yoshino, Tatsuki Teruya, Chika Miyamoto, Mai Hirose, Satoshi Endo, Akira Ikari. Unraveling the Mechanisms Involved in the Beneficial Effects of Magnesium Treatment on Skin Wound Healing. International journal of molecular sciences. 2024. 25. 9
Hiroaki Eguchi, Yaqing Yu, Toshiyuki Matsunaga, Yuta Yoshino, Akira Ikari. Acrolein suppresses anticancer drug-induced toxicity mediated by activating claudin-1 and Nrf2 axis in a spheroid model of human lung squamous cell carcinoma cells. Toxicology letters. 2024. 392. 46-55
Yuji Sakai, Daisuke Egawa, Junta Hattori, Yoshifumi Morikawa, Koichi Suenami, Tomohiro Takayama, Atsushi Nagai, Tomomi Michiue, Akira Ikari, Toshiyuki Matsunaga. α-Pyrrolidinononanophenone derivatives induce differentiated SH-SY5Y neuroblastoma cell apoptosis via reduction of antioxidant capacity: Involvement of NO depletion and inactivation of Nrf2/HO1 signaling pathway. Neurotoxicology. 2024. 100. 3-15
都築歩乃佳, 工藤優大, 吉野雄太, 遠藤智史, 五十里彰. Elucidating the effects of endoplasmic reticulum stress on androgen signaling in prostate cancer cells. 日本薬学会年会要旨集(Web). 2024. 144th
工藤優大, 坂智文, 吉野雄太, 岡田卓哉, 豊岡尚樹, 遠藤智史, 五十里彰. Development of therapeutic strategies for anticancer drug-resistant pancreatic cancer by targeting autophagy. 日本薬学会年会要旨集(Web). 2023. 143rd
工藤優大, 谷生真敏, 五十里彰, 遠藤智史. Inhibitory effects on cell proliferation of castration-resistant prostate cancer by the suppression of 11-ketoandrogen-induced androgen signaling. 日本薬学会年会要旨集(Web). 2021. 141st
太田篤実, 河合弥菜, 工藤優大, 河野真也, 市原賢二, 松永俊之, 五十里彰, 遠藤智史. The search for naturally derived ingredients to improve the treatments of prostate cancer. 日本薬学会年会要旨集(Web). 2021. 141st