Research field (2)：
Cardiology
, Molecular biology
Research keywords (2)：
循環器内科学
, Cardiovascular Medicine
Research theme for competitive and other funds (13)：
2010 - 2013 Posttranscriptional modification of cardiac transcriptional factors and its role in cardiac development
2002 - 2006 Molecular mechanism of organ remodeling : Gene transcription and cell-cell interaction in mesenchymal
2000 - 2004 細胞分化による心不全の遺伝子治療
2002 - 2003 心血管特異的薬剤誘導型遺伝子改変マウスの開発
2002 - 2002 PETを用い生体で遺伝子発現をリアルタイムにイメージングする方法の開発
2000 - 2002 Isolation and analysis of molecules which associate with Csx
2000 - 2002 Gene therapy and cell transplantation for heart failure.
2000 - 2002 Analysis for Molecular Mechanism of Cardiomyocyte Differentiation by Using a Cell Line Which Efficiently Differentiates into Cardiomyocytes
1999 - 1999 血管病変を形成する平滑筋細胞の起源の解明
GPIアンカーに重要なGPAA1の単離と機能解析
Tbx5とCsx/Nkx2-5の心臓における機能解析
Isolation and characterization of GPAA1 which is important for GPI ancha
Characterization of Tbx5 and Csx/Nkx2-5 in heart
Show all
Papers (29)：
Nobuaki Fukuma, Hiroyuki Tokiwa, Genri Numata, Kazutaka Ueda, Pangyen Liu, Miyu Tajima, Yu Otsu, Taro Kariya, Yukio Hiroi, James K Liao, et al. Endothelial estrogen - myocardial cGMP axis critically determines angiogenesis and cardiac performance during pressure-overload. Cardiovascular research. 2024
Yuichi Uchino, Masafumi Watanabe, Munenori Takata, Eisuke Amiya, Kensuke Tsushima, Takeshi Adachi, Yukio Hiroi, Toshikazu Funazaki, Issei Komuro. Effect of Oral Branched-Chain Amino Acids on Serum Albumin Concentration in Heart Failure Patients with Hypoalbuminemia: Results of a Preliminary Study. American journal of cardiovascular drugs : drugs, devices, and other interventions. 2018. 18. 4. 327-332
Koshiro Monzen, Yuzuru Ito, Atsuhiko T. Naito, Hiroki Kasai, Yukio Hiroi, Doubun Hayashi, Ichiro Shiojima, Tsutomu Yamazaki, Kohei Miyazono, Makoto Asashima, et al. A crucial role of a high mobility group protein HMGA2 in cardiogenesis. Nature Cell Biology. 2008. 10. 5. 567-574
Koichi Kimura, Katsu Takenaka, Aya Ebihara, Kansei Uno, Hiroyuki Morita, Takashi Nakajima, Tetsuo Ozawa, Izumi Aida, Yosuke Yonemochi, Shinya Higuchi, et al. A Prospective Cohort Study of Left Ventricular Noncompaction in Patients with Duchenne/Becker Muscular Dystrophy. CIRCULATION. 2012. 126. 21
K Monzen, H Kasai, Y Hiroi, D Hayashi, T Kohro, Y Imai, T Yamazaki, Komuro, I. High-mobility-group protein A2 associates with the Smad transcription factors and promotes cardiomyocyte differentiation and cardiac development. CIRCULATION. 2005. 112. 17. U518-U518
Monzen Koshiro, Hiroi Yukio, Hosoda Toru, Hayashi Doubun, Yamazaki Tsutomu, Nagai Ryouzou, Komuro Issei. FRS-011 High-Mobility-Group Protein A2 Associates with the Smad Transcription Factors and Synergistically Promotes Cardiomyocyte Differentiation(Angiogenesis and Regeneration Medicine in Cardiovascular Medicine (M) : FRS3)(Featured Research Session (English)). Circulation journal : official journal of the Japanese Circulation Society. 2004. 68. 92-92
K Monzen, H Kasai, Y Hiroi, D Hayashi, T Yamazaki, R Nagai. High-mobility-group protein A2 enhances transactivation of the CSX/NKX2-5 promoter synergistically with Smad1 and promotes cardiomyocyte differentiation. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2003. 35. 11. A26-A26
