Miyoshi Hideto

2016 - 2018 Conversion of mitochondrial respiratory complex I to a light-driven proton pump by chemical modification

2014 - 2017 Site-specific modification of respiratory complex I for single molecule analysis

2011 - 2014 Study on the function of ND1 subunit, a key subunit of respiratory complex I

2010 - 2013 Synthetic study of novel antitumor agents

2011 - 2012 Probing the intercellular traffic mechanism of ubiquinone using synthetic molecular probes

2010 - 2011 Development of conductive quinone-modified Au-electrode enabling super-sensitive detection of the activities of mitochondrial respiratory enzymes

2008 - 2010 Exploring the function of membrane domain of mitochondrial complex-I on the basis of synthesis of inhibitor probes

2006 - 2007 ミトコンドリア複合体-I活性の光制御をめざした光応答性阻害剤の合成開発

2005 - 2007 低酸素適応における寄生虫ミトコンドリア特異的呼吸酵素群の生理機能

2005 - 2006 Study on respiratory enzyme complex I based on the organic synthesis of acetogenin analogues

2004 - 2005 呼吸鎖酵素のピンポイント電子移動観測を実現する導電性阻害剤修飾電極の開発

2002 - 2005 Molecular organization and physiological functions of the respiratory chain specific for mitochondria from Plasmodium

2003 - 2004 Synthesis of functional probes toward elucidation of the function of respiratory enzymes of Caenorhabditis elegans.

2001 - 2004 Physiological function of respiratory enzymes specific for parasite mitochondria in the adaptation to low oxygen tension

2001 - 2002 マラリア原虫ミトコンドリア特異的呼吸酵素群の分子構築と生理機能

2000 - 2001 Molecular Mechanism and Structural Basis of Ubiquinone-Redox Reaction in Bacterial Respiratory Chains

1999 - 2000 Study on ubiquinol reaction site of cytochrome bo in Escherichia coli.

1997 - 1999 Structure and Function of Quinoprotein Dehydrogenase

1998 - 1998 呼吸鎖金属酵素における共鳴ラマン測定のための^<13>C-標識ユビキノン類の有機合成

1996 - 1997 Probing the ubiquinol oxidatiousite of Eschenchia col ubiquinol oxidases.

1995 - 1996 DEVELOPMENT OF TERMINAL OXIDASE-SPECIFIC BACTERIOCIDES AND BIOCHEMICAL ANALYSIS OF THE SUBSTRATE OXIDATION MECHANISM

1994 - 1995 Study on structure of cytochrome b using antimycin A-resistant mutants.

1993 - 1994 Development of new classes of flower inducing compounds and their mechanism of action.

1991 - 1991 シトクロムbcl複合体及び光合成系IIにおけるキノン結合部位の三次元構造の研究

1987 - 1987 ミトコンドリアにおける酸化的リン酸化脱共役剤の作用機構に関する研究

種々の電子伝達阻害剤の構造活性相関と作用機構の解明

Structure-activity studies of Various electron-transfer inhibitors and mode of action studies.