Rchr
J-GLOBAL ID:200901056752945156   Update date: Sep. 18, 2024

Hotokezaka Hitoshi

ホトケザカ ヒトシ | Hotokezaka Hitoshi
Affiliation and department:
Job title: 准教授
Research field  (2): Oral medicine ,  Developmental dentistry
Research keywords  (2): 歯科矯正学 ,  orthodontics
Research theme for competitive and other funds  (32):
  • 2024 - 2027 GSK3β阻害による歯根吸収抑制機構の解明-細胞死と破歯細胞活性を標的にして-
  • 2023 - 2026 歯根吸収発症における細胞小器官分解システム関連蛋白の役割
  • 2023 - 2026 変異型Rufy4を発現する破骨細胞の細胞外小胞を介した骨吸収調節機構の解明と応用
  • 2022 - 2025 オーラルフレイルが全身に及ぼす影響の解明:動物モデルの行動学的・分子生物学的解析
  • 2021 - 2025 口腔がんの進展・転移における低酸素環境下でのcPLA2の働き
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Papers (74):
  • Yukako Nashiro-Oyakawa, Yuka Hotokezaka, Hitoshi Hotokezaka, Takeshi Moriishi, Mariko Funaki-Dohi, Yosuke Iuchi, Mizuki Ohama, Yukiko Morita, Noriaki Yoshida. Inhibition of 12/15-lipoxygenase reduces orthodontically induced root resorption in rats. The Angle Orthodontist. 2024. 94. 5. 566-573
  • Jatuphol Mamani, Chidchanok Sessirisombat, Hitoshi Hotokezaka, Noriaki Yoshida, Irin Sirisoontorn. Effectiveness of Clear Aligners on Sequential Maxillary Molar Distalization: Discrepancy between Treatment Goal and Outcome. Journal of Clinical Medicine. 2024. 13. 14. 4216-4216
  • Kasidit Nitasnoraset, Apiwat Riddhabhaya, Chidchanok Sessirisombat, Hitoshi Hotokezaka, Noriaki Yoshida, Irin Sirisoontorn. Shear Bond Strength of Clear Aligner Attachment Using 4-META/MMA-TBB Resin Cement on Glazed Monolithic Zirconia. Polymers. 2024. 16. 14. 1988-1988
  • Anutta Terawatpothong, Chidchanok Sessirisombat, Wish Banhiran, Hitoshi Hotokezaka, Noriaki Yoshida, Irin Sirisoontorn. Relationship between Cephalometric and Ultrasonic Airway Parameters in Adults with High Risk of Obstructive Sleep Apnea. Journal of Clinical Medicine. 2024. 13. 12. 3540-3540
  • Yuka Hotokezaka, Takuya Nakamura, Carmen Karadeniz, Hitoshi Hotokezaka, Noriaki Yoshida. Relationship between early stage periodontal ligament compression and orthodontically induced root resorption in rats. Congress of the European Orthodontic Society Abstract Book. 2024. 163
more...
MISC (115):
  • 一瀬悠依華, 佛坂斉祉, 宮崎敏博, 森石武史, 佛坂由可, 有薗ケイラ, 中村琢也, 吉田教明. 矯正力による歯根吸収のリチウムによる抑制の組織額的解析-ラットを用いた実験-. 九州矯正歯科学会学術大会、プログラム・抄録集. 2024. 52
  • 名城友香子, 佛坂由可, 佛坂斉祉, 上田-一瀬悠依華, 西岡-坂本紀栄, 舟木真梨子, 中村琢也, 森田幸子, 井野-近藤愛理, 吉田教明. 12/15 - LOX特異的阻害剤による歯根吸収抑制とその作用機序の解明 -ラットを用いた実験-. 九州矯正歯科学会学術大会、プログラム・抄録集. 2024. 51
  • 中村琢也, 佛坂由可, 佛坂斉祉, 坂本紀栄, 名城-親川友香子, 舟木-土肥真梨子, 吉田教明. 矯正力負荷早期における歯根膜腔狭小化と歯根吸収の相関関係. 九州矯正歯科学会学術大会、プログラム・抄録集. 2024. 51
  • 舟木-土肥, 真梨子, 佛坂, 斉祉, 佛坂, 由可, 一瀬, 悠依華, 坂本, 紀栄, et al. リチウムは矯正力負荷初期の短期間投与でも歯根吸収抑制効果を示すのか?. 九州矯正歯科学会学術大会、プログラム・抄録集. 2024. 53
  • Inhibitory effect of initial short-time administration of lithium on orthodontically induced resorption. The 82st Annual Meeting of the Japanese Orthodontic Society. 2023. 181-181
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Books (2):
  • Impacted teeth
    2015 ISBN:9784781204185
  • チェアサイドの歯科英会話
    医歯薬出版 2011
Lectures and oral presentations  (37):
  • 小胞体ストレスを介した細胞死における細胞質ATMの関与
    (第 30 回日本 Cell Death 学会学術集会 2022)
  • Enhanced Fixation of Orthodontic Anchor Screws Using β-TCP-An Experiment Using Rats-
    (The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress. 2021)
  • Effect of administration of botulinum toxin type A in masseter on tooth movement in rats
    (The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress. 2021)
  • Suppression of orthodontic root resorption by lithium and elucidation of its mechanism
    (The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress. 2021)
  • Effects of Lithium chloride on alveolar bone morphometry, tooth movement and root resorption in rats
    (The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress. 2021)
more...
Works (12):
  • アポトーシス阻害剤による歯根吸収の抑制効果の検討
    2009 - 2010
  • 病的歯根吸収の再石灰化治癒機転の研究
    2007 - 2009
  • MAPK 制御による病的歯根吸収の抑制の試み
    2003 - 2005
  • 急性炎症性サイトカインを誘導するストレスタンパク質の病的歯根吸収に及ぼす影響研究
    2001 - 2003
  • ストレスタンパク質の骨吸収に与ぼす影響
    2001 -
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Education (2):
  • 1994 - 1994 Doctor of Philosophy
  • 1980 - 1986 Nagasaki University School of Dentistry
Professional career (1):
  • (BLANK)
Work history (6):
  • 2014/12 - 現在 Nagasaki University Graduate School of Biomedical Sciences Department of Orthodontics and Dentofacial Orthopedics Associate professor
  • 2004/12 - 2014/12 Nagasaki University Graduate School of Biomedical Sciences Diveision of Orthodontics and Dentofacial Orthopedics Lecturer
  • 1992/04 - 2004/11 Nagasaki University School of Dentistry Department of Orthodontics Assistant professor
  • 1997/10 - 2000/03 Memorial Sloan-Kettering Cancer Center Cellular biochemistry and Biophysics Program Postdoctorial Fellow
  • 1987/04 - 1992/03 Nagasaki University School of Detistry, Dental Hospital Orthodontics Assistant professor
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Committee career (9):
  • 2017/10 - 現在 長崎大学 情報セキュリティ・情報システム管理委員会委員
  • 2012/04 - 現在 九州矯正歯科学会 評議員
  • 2021/04 - 2024/03 長崎大学 数理データサイエンス小委員会委員
  • 2021/04 - 2024/03 長崎大学 歯学部再任委員会委員
  • 2020/04 - 2024/03 長崎大学 キャリアセンター運営委員会委員
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Awards (7):
  • 2024/07 - Japan Orthodotontic Society 日本矯正歯科学会学術奨励賞 Fixation of an orthodontic anchor screw using beta-tricalcium phosphate in a screw-loosening model in rats.
  • 2024/06 - 99th EUROPEAN ORTHODONTIC SOCIETY CONGRESS Best Poster Award Inhibition of 12/15-lipoxygenase reduces orthodontically induced root resorption by suppressing hyaline degeneration and subsequent odotoclast differentiation in rats
  • 2022/10 - The 81st Annual Meeting of the Japanese Orthodontic Society & The 9th Joint Symposium of the Japanese Orthodontic Society and Korean Association of Ortodontists. Excellent Presentation Award Construction of an orthodontic anchor screw loosening model and investigation of anchor screw fixation effects using β-TCP
  • 2021/11 - The 80th Annual Meeting of Japan Orthodontic Society & The 5th International Congress Excellent Presentation Award
  • 2010 - The 69th Annual Meeting of Japan Orthodontic Society Excellent Presentation Award Repair of orthodontically induced root resorption following continuous force application
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Association Membership(s) (9):
日本口蓋裂学会 ,  日本顎変形症学会 ,  九州矯正歯科学会 ,  日本骨代謝学会 ,  歯科基礎医学会 ,  日本細菌学会 ,  西日本矯正歯科学会 ,  日本矯正歯科学会 ,  World Federation of Orthodontists
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