Research field (5):
Structural biochemistry
, Bacteriology
, Applied microbiology
, Applied biochemistry
, Biophysics
Research keywords (1):
Structural Biology, Bacteriology, Biofilm, Electron microscopy, Gene engineering, Single particle reconstruction
Research theme for competitive and other funds (17):
2022 - 2025 バクテロイデーテス細菌の滑走運動によるバイオフィルム拡張メカニズムの解明
2019 - 2023 Technology development and application for cell surface visual proteomics
2019 - 2022 Control of the Protein secretion system of periodontal bacteria
2016 - 2018 スパースモデリングによる電顕単粒子構造解析の迅速・高分解能化
2015 - 2018 Development of fluorescence labeling methods of proteins in cells and tissues for high-resolution correlated light-electron microscopy (CLEM) using Atmospheric scanning electron microscopy
2015 - 2017 Development of technical basis for direct observations of membrane protein complex in dynamic equilibrium under a physiological condition
2013 - 2017 Study for mechanism of ABC transporters based on single molecular direct observations using high speed Atomic Force Microscopy.
2014 - 2016 Advanced technology development for analyzing molecular dynamics and structure in synapse formation
2010 - 2016 Structural basis of cell-signaling complexes mediating signal perception, transduction and responses.
2012 - 2015 Surfactant-associated protein imaging in alveolar epithelialcells by Atmospheric Scanning Electron Microscope
2010 - 2015 Electron microscopy of structure and localization of signal processing complexes
2010 - 2012 Study for ATP-driven transport mechanism of ABC transporters based on the "ATP hydrolysis switch" hypothesis.
2004 - 2009 Development of single particle electron microscopy
2004 - 2009 Functional Mechanism and Structural Organization of Biological Macromolecular Assemblies
2004 - 2005 Dynamic structural rearrangements of ion channels and receptors dependent on expression density.
2003 - 2004 細菌由来電位依存性カチオンチャネルを用いた新規蛍光膜電位レポーターの開発
ナトリウムチャンネルの3次元構造
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Papers (177):
Tianxu Gao, Takehiro Yachi, Xu Shi, Rina Sato, Chikara Sato, Yusuke Yonamine, Kiyoshi Kanie, Hiroaki Misawa, Kuniharu Ijiro, Hideyuki Mitomo. Ultrasensitive Surface-Enhanced Raman Scattering Platform for Protein Detection via Active Delivery to Nanogaps as a Hotspot. ACS Nano. 2024
Chikara Sato, Keiko Sato. Social Motility Assays of Flavobacterium johnsoniae. Methods in molecular biology (Clifton, N.J.). 2023. 2646. 287-298
Yoshio Kondo, Kenichi Ohara, Ryoji Fujii, Yudai Nakai, Chikara Sato, Mariko Naito, Takayuki Tsukuba, Tomoko Kadowaki, Keiko Sato. Transposon mutagenesis and genome sequencing identify two novel, tandem genes involved in the colony spreading of Flavobacterium collinsii, isolated from an ayu fish, Plecoglossus altivelis. Frontiers in cellular and infection microbiology. 2023. 13. 1095919-1095919
Yuko Takagi, Mari Sato, Masami Naya, Chikara Sato. Differentiating Trypanosoma cruzi in a Host Mammalian Cell Imaged in Aqueous Liquid by Atmospheric Scanning Electron Microscopy. Microbiology spectrum. 2022. e0141321