Rchr
J-GLOBAL ID:200901056881517829
Update date: Nov. 03, 2024
Toyoda Taro
トヨダ タロウ | Toyoda Taro
Affiliation and department:
Job title:
Junior Associate Professor
Homepage URL (1):
https://sites.google.com/view/toyodatgroup/%E3%83%9B%E3%83%BC%E3%83%A0
Research field (1):
Metabolism and endocrinology
Research keywords (8):
cell therapy
, islet transplantation
, regenerative medicine
, iPS cell
, pancreas
, 5'AMP-activated protein kinase
, glucose transport
, skeletal muscle
Research theme for competitive and other funds (12):
- 2022 - 2025 ヒトiPS細胞由来分化細胞を用いた新規老化モデルの構築と可塑性の検証
- 2023 - 2024 Development of iPS cell-derived pancreatic islet cell (iPIC) therapy for type 1 diabetes
- 2023 - 2024 Mesh Oxygen Transporter for improved engraftment of human stem cell-derived pancreatic islet cells in the subcutaneous site
- 2019 - 2022 iPS細胞由来膵島細胞(iPIC)を用いた1型糖尿病に対する細胞治療の製造法開発及び非臨床試験の実施
- 2018 - 2021 Molecular mechanisms regulating the differentiation for pancreatic bud-like cells from human pluripotent stem cells
- 2015 - 2018 Mechanism based development of differentiation method for pancreatic bud-like cells from human pluripotent stem cells
- 2013 - 2015 Development and verification of implantable pancreatic epithelial cells from human pluripotent stem cell
- 2011 - 2013 Action mechanism of functional food and natural medicine focusing on AMP kinase and related signaling molecules in skeletal muscle
- 2011 - 2012 Generation of pancreatic beta cell from human pluripotent stem cell by use of the purification with flow cytometry
- 2009 - 2010 運動後の骨格筋糖輸送促進のメカニズム解明-AS160の調節と役割
- 2004 - 2005 運動時のエネルギー代謝調節における骨格筋AMPキナーゼの意義に関する研究
- 2001 - 骨格筋糖代謝における酸化ストレスの意義
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Papers (55):
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Daiki Fukai, Taro Toyoda, Hidekuni Takao, Fusao Shimokawa, Kyohei Terao. Compartmentalization Device of Microenvironment for Analyzing iPSCs Differentiation. IEEJ Transactions on Sensors and Micromachines. 2024. 144. 7. 164-169
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Hideyuki Hiyoshi, Kensuke Sakuma, Shinya Asano, Stephanie C Napier, Shuhei Konagaya, Taisuke Mochida, Hikaru Ueno, Takeshi Watanabe, Yoshiaki Kassai, Hirokazu Matsumoto, et al. Identification and removal of unexpected proliferative off-target cells emerging after iPSC-derived pancreatic islet cell implantation. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 16. e2320883121
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Ryo Ito, Azuma Kimura, Yurie Hirose, Yu Hatano, Atsushi Mima, Shin-Ichi Mae, Yamato Keidai, Toshihiro Nakamura, Junji Fujikura, Yohei Nishi, et al. Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model. Scientific reports. 2023. 13. 1. 8659-8659
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Kensuke Sakuma, Noriko Tsubooka-Yamazoe, Kiyohiro Hashimoto, Nozomu Sakai, Shinya Asano, Saori Watanabe-Matsumoto, Takeshi Watanabe, Bunnai Saito, Hirokazu Matsumoto, Hikaru Ueno, et al. CDK8/19 inhibition plays an important role in pancreatic β-cell induction from human iPSCs. Stem cell research & therapy. 2023. 14. 1. 1-1
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Yuta Tsujisaka, Takeshi Hatani, Chikako Okubo, Ryo Ito, Azuma Kimura, Megumi Narita, Kazuhisa Chonabayashi, Shunsuke Funakoshi, Antonio Lucena-Cacace, Taro Toyoda, et al. Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting. Stem cell reports. 2022. 17. 7. 1772-1785
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MISC (80):
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小長谷周平, 末永亮, 山浦順司, 山浦順司, 伊藤亮, 田中郷史, 石崎庸一, 豊田太郎, 豊田太郎. 多孔培養バッグを用いた均一細胞凝集塊の大量作製. 日本再生医療学会総会(Web). 2022. 21st
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小長谷周平, 小長谷周平, 末永亮, 山浦順司, 山浦順司, 伊藤亮, 伊藤亮, 田中郷史, 石崎庸一, 豊田太郎, et al. 多孔培養バッグを用いた均一な膵島様凝集塊の作製. 日本膵・膵島移植研究会プログラム・抄録集. 2021. 48th
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木村東, 豊田太郎, 岩崎未央, 平間竜介, 長船健二. 再生医療応用に向けたヒトES/iPS細胞由来膵前駆細胞の増殖機序の解明. 日本再生医療学会総会(Web). 2021. 20th
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穴澤貴行, 多田誠一郎, 山根佳, 井ノ口健太, 江本憲央, 藤本七恵, 藤倉純二, 稲垣暢也, 豊田太郎, 坂口志文. 膵島移植と再生医療. 日本再生医療学会総会(Web). 2021. 20th
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木村東, 豊田太郎, 岩崎未央, 平間竜介, 長船健二. 糖尿病に対する細胞療法確立に向けたヒトES/iPS細胞由来膵前駆細胞の増殖機序の解明. 糖尿病(Web). 2021. 64. Suppl
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Patents (55):
Books (12):
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小児・思春期糖尿病コンセンサス・ガイドライン
南江堂 2024 ISBN:9784524203895
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糖尿病最新の治療2022-2024
南江堂 2021 ISBN:9784524229963
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糖尿病 最新の治療2019-2021
南江堂 2019 ISBN:9784524245567
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再生医療
南江堂 2015
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糖尿病学
西村書店 2015
more...
Lectures and oral presentations (115):
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Generation of iPSC-derived islet cells (iPICs) for their clinical applications
(The 67th Annual Meeting of the Japan Diabetes Society 2024)
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細胞の分化誘導環境を探索する微小溶液環境区画化デバイスの開発
(第40回「センサ・マイクロマシンと応用システム」シンポジウム 2023)
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Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model
(International Diabetes Federation Western Pacific Region Congress 2023 15th Scientific Meeting of the Asian Association for the Study of Diabetes 2023)
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Strategies for reducing non-endocrine cells in stem cell-derived islets
(4th IPITA/HSCI/JDRF summit 2023 2023)
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膵内分泌細胞誘導因子ALK5 inhibitor IIの置き換えによる造腫瘍性懸念の回避
(第22回日本再生医療学会総会 2023)
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Education (5):
- 2003 - 2006 Kyoto University Graduate School of Agriculture
- 2001 - 2003 Kyoto University Graduate School of Agriculture
- - 2003 Kyoto University Graduate School, Division of Agriculture
- 1997 - 2001 Kyoto University Faculty of Agriculture
- - 2001 Kyoto University Faculty of Agriculture
Professional career (1):
- Doctor of Agriculture (Kyoto University)
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