Kakizaki Toshikazu

カキザキトシカズ | Kakizaki Toshikazu

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Neuroscience - general

Research theme for competitive and other funds (8)：

2019 - 2022 Evaluation of central visual deficits in GAD KO rats
2014 - 2018 Study of GABAergic transmission mechanism using glutamate decarboxylase knockout mice
2010 - 2012 Study of the mechanisms of GABAergic neurotransmission using inducible glutamate decarboxylase knockout mice
2008 - 2009 興奮性ニューロンと抑制性ニューロンとを識別するトランスジェニック動物の開発
2007 - 2008 性行動と母性行動の発達における神経伝達物質、GABAの役割、パート2

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Papers (20)：

Kazuki Komiyama, Keiya Iijima, Reika Kawabata-Iwakawa, Kazuyuki Fujihara, Toshikazu Kakizaki, Yuchio Yanagawa, Yuhei Yoshimoto, Shigeo Miyata. Glioma facilitates the epileptic and tumor-suppressive gene expressions in the surrounding region. Scientific reports. 2022. 12. 1. 6805-6805
Weiru Jiang, Toshikazu Kakizaki, Kazuyuki Fujihara, Shigeo Miyata, Yue Zhang, Takashi Suto, Daiki Kato, Shigeru Saito, Koji Shibasaki, Yasuki Ishizaki, et al. Impact of GAD65 and/or GAD67 deficiency on perinatal development in rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022. 36. 2. e22123
Shigeo Miyata, Toshikazu Kakizaki, Kazuyuki Fujihara, Hideru Obinata, Touko Hirano, Junichi Nakai, Mika Tanaka, Shigeyoshi Itohara, Masahiko Watanabe, Kenji F. Tanaka, et al. Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice. Molecular Brain. 2021. 14. 1
Azumi Noguchi, Kenji Ito, Yuichi Uosaki, Maky Ideta-Otsuka, Katsuhide Igarashi, Hideyuki Nakashima, Toshikazu Kakizaki, Ruri Kaneda, Hideki Uosaki, Yuchio Yanagawa, et al. Decreased Lamin B1 Levels Affect Gene Positioning and Expression in Postmitotic Neurons. Neuroscience Research. 2021
Kazuyuki Fujihara, Kazuo Yamada, Yukio Ichitani, Toshikazu Kakizaki, Weiru Jiang, Shigeo Miyata, Takashi Suto, Daiki Kato, Shigeru Saito, Masahiko Watanabe, et al. CRISPR/Cas9-engineered Gad1 elimination in rats leads to complex behavioral changes: implications for schizophrenia. Translational Psychiatry. 2020. 10. 1

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MISC (18)：

藤原和之, 藤原和之, 柿崎利和, JIANG Weiru, 宮田茂雄, 宮田茂雄, 須藤貴史, 齋藤繁, 山田一夫, 一谷幸男, et al. GAD67ノックアウトラットの認知機能障害. 日本生物学的精神医学会(Web). 2019. 41st
Ayae Nishiyama, Hideki Shimomura, Nobuko Kanbara-Kume, Toshikazu Kakizaki, Takakuni Tanizawa, Yuchio Yanagawa, Akiko Arata. The behavioral development in the GlyT2-deficient mice. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S145-S145
藤原和之, 三輪秀樹, 柿崎利和, 三國雅彦, 棚平千代子, 玉巻伸章, 柳川右千夫. GABA仮説に基づく統合失調症モデルマウスの開発と解析. The Kitakanto medical journal. 2011. 61. 3. 456-456
Kazuyuki Fujihara, Hideki Miwa, Toshikazu Kakizaki, Masahiko Mikuni, Chiyoko Tanahira, Nobuaki Tamamaki, Yuchio Yanagawa. Parvalbumin-positive neuron-specific GAD67 knockout mice exhibit schizophrenia-like phenotypes. NEUROSCIENCE RESEARCH. 2011. 71. E298-E298
Toshikazu Kakizaki, Mikiko Kayakabe, Ryosuke Kaneko, Hiromitsu Saito, Noboru Suzuki, Yuchio Yanagawa. Generation and analysis of cerebellar Purkinje cell-specific VGAT knockout mice. NEUROSCIENCE RESEARCH. 2011. 71. E114-E114

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Lectures and oral presentations (47)：

GAD65欠損ラットは脳内GABA含量の減少とてんかん重積状態を示す
(第42回日本神経科学大会 2019)
Glutamate decarboxylase 65-deficient rats exhibit decreased brain GABA content and premature lethality
(The 41st Annual Meeting of the Japan Neuroscience Society 2018)
Decreased GABA content and premature lethality in glutamate decarboxylase 65-deficient rats
(11th FENS Forum of Neuroscience 2018)
Premature lethality in glutamate decarboxylase 65-deficient rats
(The 40th Annual Meeting of the Japan Neuroscience Society 2017)
Phenotypic comparison between glutamate decarboxylase 65 knockout mice and rats
(The 39th Annual Meeting of the Japan Neuroscience Society 2016)

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Education (3)：

1997 - 2001 Niigata University Graduate School of Medicine
1995 - 1997 新潟大学大学院自然科学研究科生体機能専攻博士前期過程
1991 - 1995 Niigata University Faculty of Science Department of Biology

Professional career (1)：

条件付必須項目の入力がありません (Niigata University)

Work history (8)：

2003 - 2004 Niigata University Brain Research Institute
2004 - - 群馬大学大学院医学系研究科遺伝発達行動学助教
2001 - 2003 Niigata University Brain Research Institute
2001 - 2001 Niigata University Brain Research Institute
1997 - 2001 Niigata University Graduate School of Medicine

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