Rchr
J-GLOBAL ID:200901058134562567
Update date: Oct. 07, 2024
Nakayama Misako
ナカヤマ ミサコ | Nakayama Misako
Affiliation and department:
Job title:
Postdoctoral researcher with an EU MCSA fellowship
Homepage URL (1):
https://www.helmholtz-munich.de/en/lhi
Research field (4):
Virology
, Immunology
, Laboratory animal science
, Experimental pathology
Research keywords (7):
Nonhuman primate model
, Mucosal Immunity
, Host-Pathogen Interaction
, SARS-CoV-2
, Influenza virus
, Vaccination
, Airway organoid
Research theme for competitive and other funds (7):
- 2023 - 2025 Epithelial-mesenchymal crosstalk in the pathology of influenza virus infection: https://cordis.europa.eu/project/id/101107766
- 2020 - 2022 Revealing pathology of COPD exacerbation caused by influenza virus in an in vitro COPD model
- 2020 - 2022 Elucidation of mechanisms involved in increased severety of influenza virus infection by using in vitro models of asthma and COPD
- 2016 - 2019 Elucidation of regulatory mechanisms of latent TGF-β expression on human monocytes and functional differences in monocytes based on the proportion of latent TGF-β expression
- 2018 - 2018 Grants for overseas study for postdoctoral researchers
- 2015 - 2018 Search for host factors in severe influenza virus infection using a nonhuman primate model
- 2017 - 2018 Grants for overseas study for young academic staffs
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Papers (45):
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Cong Thanh Nguyen, Misako Nakayama, Hirohito Ishigaki, Yoshinori Kitagawa, Akemi Kakino, Marumi Ohno, Masashi Shingai, Yasuhiko Suzuki, Tatsuya Sawamura, Hiroshi Kida, et al. Increased expression of CD38 on endothelial cells in SARS-CoV-2 infection in cynomolgus macaque. Virology. 2024. 110052-110052
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Hirohito Ishigaki, Sayaka Ito, Takako Sasamura, Hideaki Ishida, Misako Nakayama, Cong Thanh Nguyen, Takaaki Kinoshita, Shingo Suzuki, Chizuru Iwatani, Hideaki Tsuchiya, et al. MHC-DRB alleles with amino acids Val11, Phe13, and the shared epitopes promote collagen-induced arthritis and a rapid IgG1 response in Filipino cynomolgus macaques. HLA. 2024. 103. 1
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Shino Shimizu, Misako Nakayama, Cong Thanh Nguyen, Hirohito Ishigaki, Yoshinori Kitagawa, Fumihiko Yasui, Yoshiki Yagi, Tomoe Kusayanagi, Michinori Kohara, Yasushi Itoh, et al. SARS-CoV-2 induces inflammation and intracranial infection through the olfactory epithelium-olfactory bulb pathway in non-human primates. Journal of Neuroimmunology. 2024. 578288-578288
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Eri Kawakami, Norikazu Saiki, Yosuke Yoneyama, Chiharu Moriya, Mari Maezawa, Shuntaro Kawamura, Akiko Kinebuchi, Tamaki Kono, Masaaki Funata, Ayaka Sakoda, et al. Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19. Cell stem cell. 2023. 30. 10. 1315-1330
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Jie Chen, Xinyuan Wang, Adrian Schmalen, Sophia Haines, Martin Wolff, Huan Ma, Huabin Zhang, Mircea Gabriel Stoleriu, Johannes Nowak, Misako Nakayama, et al. Antiviral CD8+ T-cell immune responses are impaired by cigarette smoke and in COPD. The European respiratory journal. 2023. 62. 2
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MISC (55):
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塩原 正規, 仲山 美沙子, 石垣 宏仁, 伊藤 靖. インフルエンザ不活化全粒子ワクチンはB細胞の体細胞高頻度突然変異を誘導する。. 日本病理学会会誌. 2023. 112. 1. 242-242
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仲山 美沙子, 北川 直子, 石垣 宏仁, Nguyen Thanh Cong, 石田 英明, 鈴木 紗織, 小笠原 一誠, 伊藤 靖. サルにおけるH5N1不活化全粒子ワクチン接種5年後の肺炎予防効果. 日本病理学会会誌. 2023. 112. 1. 242-242
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森河 友里, 仲山 美沙子, 笹村 孝子, 石垣 宏仁, 伊藤 靖. 慢性呼吸器疾患患者由来の気道オルガノイドにおけるインフルエンザおよび新型コロナウイルス受容体の発現. 日本病理学会会誌. 2023. 112. 1. 382-382
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清水 志乃, 仲山 美沙子, 石垣 宏仁, Nguyen Thanh Cong, 北川 善紀, 伊藤 靖, 清水 猛史. 「感染・免疫研究の新潮流」 非ヒト霊長類の嗅上皮から嗅球におけるSARS-CoV-2感染の病態. 日本耳鼻咽喉科免疫アレルギー感染症学会抄録集. 2023. 3回. 84-84
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塩原 正規, 仲山 美沙子, 石垣 宏仁, 伊藤 靖. インフルエンザ不活化全粒子ワクチンはB細胞の体細胞高頻度突然変異を誘導する。. 日本病理学会会誌. 2023. 112. 1. 242-242
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Patents (3):
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SARS-CoV-2 NEUTRALIZING ANTIBODY OR FRAGMENT THEREOF
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METHOD FOR IN VITRO PROLIFERATING VIRUS BELONGING TO FAMILY CORONAVIRIDAE, METHOD FOR PRODUCING NEUTRALIZING ANTIBODY TO VIRUS BELONGING TO FAMILY CORONAVIRIDAE, AND METHOD FOR PRODUCING INFECTION MODEL OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
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細胞補集材及び細胞補集用カラム
Lectures and oral presentations (103):
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Establishment of an airway epithelium-fibroblast coculture model for respiratory viral infection and spatial transcriptomics
(12th DZL Annual Meeting, GIESSEN/MARBURG/BAD NAUHEIM SITE 2024)
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Expression of avian-type flu receptor is negatively correlated with differentiation in primary human bronchial epithelial cells
(European Respiratory Society International Congress 2023, Milan, Italy 2023)
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Influenza and SARS-CoV-2 receptors in an airway organoid from patients with chronic lung diseases
(The 112th annual congress of Japanese Society of Pathology 2023)
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Inactivated whole influenza virus particle vaccines promote somatic hypermutation in B-lymphocytes
(The 112th annual congress of Japanese Society of Pathology 2023)
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Five-year efficacy of an H5N1 inactivated whole virus particle vaccine against pneumonia in monkeys
(The 112th annual congress of Japanese Society of Pathology 2023)
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Education (3):
- 2009 - 2014 Shiga University of Medical Science Faculty of Medicine, PhD course
- 2000 - 2006 Shiga University of Medical Science Faculty of Medicine
- 2005 - 2005 St George's University of London Medical Oncology
Work history (7):
- 2023/09 - 現在 Helmholtz Center Munich Institute of Lung Health and Immunity Postdoctoral researcher with an EU MCSA fellowship
- 2008/12 - 2023/08 Shiga University of Medical Science Department of Pathology Assistant Professor
- 2017/11 - 2019/03 Helmholtz Center Munich Comprehensive Pneumology Center Guest Scientist
- 2017/01 - 2017/05 Parental Leave
- 2011/01 - 2011/05 Parental Leave
- 2008/04 - 2008/11 Shiga University of Medical Science Department of Pathology Medical Staff
- 2006/04 - 2008/03 Hikone Municipal Hospital Clinical Training
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Awards (6):
Association Membership(s) (3):
European Respiratory Society
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, THE JAPANESE SOCIETY OF PATHOLOGY
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