Rchr
J-GLOBAL ID:200901058167269636
Update date: Sep. 16, 2024
Kijima Hiroshi
キジマ ヒロシ | Kijima Hiroshi
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://www.med.hirosaki-u.ac.jp/~patho2/
Research field (2):
Human pathology
, Molecular biology
Research keywords (4):
分子生物学
, 人体病理学
, Molecular Biology
, Human Pathology
Research theme for competitive and other funds (26):
- 2022 - 2025 Elucidation of perineural invasion of distal cholangiocarcinoma using tissue clearing method
- 2021 - 2024 胆膵癌の概日リズムに関連した高悪性度形質とその制御
- 2018 - 2022 Pathophysiology and growth control of the microenvironment in colorectal cancer with highly invasive growth
- 2018 - 2021 Breast cancer microenvironment control targeting clock gene and its development of MRI imaging
- 2017 - 2020 Pathophysiological modulation of high-grade malignant potentials of pancreato-biliary cancer, and its clinical application
- 2016 - 2019 Breast cancer microenvironment control targeting clock gene and its clinical application
- 2016 - 2019 Study of the prevention and complementary treatment of advanced cancer: Examination of presymptomatic diagnosis and reactivation of cancer suppression mechanism
- 2015 - 2018 Functional analysis of "angio-lymphatic vessels" in the neoplastic lesions - its histopathological significance
- 2013 - 2016 The use of fluorescent L-glucose derivative as a marker of early gastro-colonic cancer on routine endoscopy.
- 2010 - 2012 The study of the development of anti-cancer drug which targets human septin 4 (Bradeion) GTPase
- 2011 - 2011 Functional alalysis of clock genes in highly aggressive pancreato-biliary cancer
- 2008 - 2010 Clock genes regulates tumor growth and tumor angiogenesis of human pancreato-biliary cancer.
- 2007 - 2008 Histological analysis of the osteochondritis dissecans
- 2006 - 2007 Development of cancer therapeutic technology by functional measurement and control of cell division.
- 2005 - 2006 Pathology and molecular targeting of human pancreatic cancer
- 2003 - 2004 Development of monitoring system of colorectal cancer
- 2002 - 2003 Antioxidant Agents Therapy for Esophageal Mucosa with Inducible Nitric Oxide Syntlaase Expression
- 2000 - 2001 Bradeion, the gene expressed in colorectal cancer specifically --its functional analysis and technical development of clinical application--
- 2000 - 2001 Characterization of ras oncogene functions in human cancer using ribozyme-mediated specific gene modulation
- 1999 - 2001 食道の老化
- 1999 - 2000 Knock-down mouse, a novel gene engineering mouse for use as a disease model
- 1998 - 2000 Regulation of pancreatic β-cell function by glutathione
- 1997 - 1998 Intracellular localization of multidrug resistance associated protein (MRP) and atypical multidrug resistance phenomenon in non-small cell lung cancer
- 1997 - 1998 Anti-oncogene hammerhead ribozymes (RNA enzymes) specifically inhibit oncogens in a mice model system.
- Specific modulation of gene expression
- Molecular Biology of Cancer
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Papers (162):
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Shunsuke Kubota, Takuya Miura, Taiichi Wakiya, Tadashi Yoshizawa, Shintaro Goto, Hajime Morohashi, Yoshiyuki Sakamoto, Yota Tatara, Hiroshi Kijima, Kenichi Hakamada. Exploration of Malignant Characteristics in Neoadjuvant Chemotherapy-Resistant Rectal Cancer, Focusing on Extramural Lesions. Annals of surgical oncology. 2023
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Keisuke Yamazaki, Taiichi Wakiya, Keinosuke Ishido, Norihisa Kimura, Daichi Ichinohe, Yoshiya Takahashi, Tadashi Yoshizawa, Hiroshi Kijima, Kenichi Hakamada. A case of serous cystic neoplasm with tumor growth acceleration leading to extrapancreatic invasion. Clinical journal of gastroenterology. 2023. 16. 2. 289-296
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Shintaro Goto, Tadashi Yoshizawa, Keinosuke Ishido, Hiroko Seino, Satoko Morohashi, Hirokazu Ogasawara, Shunsuke Kubota, Kenta Ogasawara, Akie Nakamura, Kenichi Hakamada, et al. Use of time-density curves of dynamic contrast-enhanced computed tomography for determination of the histological therapeutic effects of neoadjuvant chemotherapy for pancreatic ductal adenocarcinoma. Oncology reports. 2023. 49. 3
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Takafumi Yachi, Tadashi Yoshizawa, Norihisa Kimura, Hiroko Seino, Satoko Morohashi, Shintaro Goto, Keinosuke Ishido, Hiroshi Kijima, Kenichi Hakamada. 18F-fluorodeoxyglucose positron emission tomography predicts recurrence and histological grade of extrahepatic bile duct cancer. Oncology letters. 2023. 25. 3. 125-125
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Hirokazu Ogasawara, Tadashi Yoshizawa, Kiyoko Oshima, Kenta Ogasawara, Shunsuke Kubota, Shintaro Goto, Satoko Morohashi, Taiichi Wakiya, Norihisa Kimura, Keinosuke Ishido, et al. Three-dimensional analysis of perineural invasion in extrahepatic cholangiocarcinoma using tissue clearing. Pathology oncology research : POR. 2023. 29. 1611284-1611284
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MISC (105):
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田中 壽和, 田中 芳美, 野呂 大輔, 杉山 尚樹, 鈴木 裕一朗, 岡本 亜希子, 山本 勇人, 今井 篤, 畠山 真吾, 米山 高宏, et al. 腎原発神経内分泌腫瘍の一例. 泌尿器外科. 2016. 29. 2. 187-187
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Yakoshi Yuta, Kudo Daisuke, Toyoki Yoshikazu, Isido Keinosuke, Kimura Norihisa, Wakiya Taiichi, Sakuraba Shingo, Yoshizawa Tadashi, Sakamoto Yoshiyuki, Kijima Hiroshi, et al. Non-Invasive Quantification of Liver Damage by a Novel Application for Statistical Analysis of Ultrasound Signals. The Hirosaki medical journal. 2014. 65. 2. 199-208
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脇屋 太一, 工藤 大輔, 豊木 嘉一, 石戸 圭之輔, 木村 憲央, 矢越 雄太, 鳴海 俊治, 鬼島 宏, 袴田 健一. PS-214-6 大腸癌肝転移切除症例における化学療法による肝障害度とICG検査との相関について(PS ポスターセッション,第113回日本外科学会定期学術集会). 日本外科学会雑誌. 2013. 114. 2. 820
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脇屋太一, 工藤大輔, 豊木嘉一, 石戸圭之輔, 木村憲央, 矢越雄太, 鳴海俊治, 鬼島宏, 袴田健一. 大腸癌肝転移切除症例における化学療法による肝障害度とICG検査との相関について. 日本外科学会雑誌. 2013. 114
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工藤大輔, 豊木嘉一, 石戸圭之輔, 木村憲央, 脇屋太一, 村田曉彦, 小山基, 坂本義之, 諸橋一, 矢越雄太, et al. 大腸癌肝転移;Consensus&Controversy 薬物療法;最近のトピックス 化学療法による肝障害. 肝胆膵. 2013. 67. 4
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Education (4):
- - 1988 Niigata University Graduate School of Medicine
- - 1988 Niigata University Graduate School, Division of Medicine
- - 1984 Niigata University Faculty of Medicine School of Medicine
- - 1984 Niigata University Faculty of Medicine
Professional career (2):
Work history (7):
- 2007/04 - Hirosaki University Graduate School of Medicine
- 2004/08 - 2007/03 Hirosaki University School of Medicine
- 2003/04 - 2004/07 Tokai University School of Medicine
- 1997/04 - 2003/03 Tokai University School of Medicine
- 1996/04 - 1997/03 大和市立病院 病理(出向)
- 1988/07 - 1997/03 Tokai University School of Medicine
- 1993/06 - 1995/12 City of Hope National Medical Center, California, USA Visiting Investigator
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Association Membership(s) (6):
American Association for Cancer Research
, 日本臨床細胞学会
, 日本胆道学会
, 日本消化器病学会
, 日本癌学会
, 日本病理学会
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