Rchr
J-GLOBAL ID:200901059393263043   Update date: Mar. 07, 2024

Takahashi Masahiko

タカハシ マサヒコ | Takahashi Masahiko
Affiliation and department:
Job title: Associate Professor
Research field  (3): Pathobiochemistry ,  Cell biology ,  Virology
Research keywords  (5): アグリソーム ,  ストレス顆粒 ,  細胞死 ,  神経変性疾患 ,  ヒトT細胞白血病ウイルス1型
Research theme for competitive and other funds  (7):
  • 2021 - 2024 多発性骨髄腫患者にて分子標的薬ダラツムマブによる輸血検査偽陽性の新規回避法の確立
  • 2017 - 2020 新規NF-κB抑制因子による炎症性腸疾患における慢性炎症の制御機構
  • 2017 - 2020 プロテアソーム阻害薬に対する感受性を抑制する新しい分子機構の解明
  • 2016 - 2018 ストレス顆粒とオートファジーによるTDP-43蛋白の分解機構
  • 2014 - 2017 活性酸素制御異常による成人T細胞白血病発症機構の解明
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Papers (39):
  • Kanako Watanabe, Tomoichiro Oka, Hirotaka Takagi, Sergei Anisimov, Shun-ichi Yamashita, Yoshinori Katsuragi, Masahiko Takahashi, Masaya Higuchi, Tomotake Kanki, Akihiko Saitoh, et al. Myeloid-associated differentiation marker is an essential host factor for human parechovirus PeV-A3 entry. Nature Communications. 2023. 14. 1
  • Masahiko Takahashi, Hiroki Kitaura, Akiyoshi Kakita, Taichi Kakihana, Yoshinori Katsuragi, Osamu Onodera, Yuriko Iwakura, Hiroyuki Nawa, Masaaki Komatsu, Masahiro Fujii. USP10 inhibits aberrant cytoplasmic aggregation of TDP-43 by promoting stress granule clearance. Molecular and Cellular Biology. 2022. 42. 3. e0039321
  • Junya Sango, Taichi Kakihana, Masahiko Takahashi, Yoshinori Katsuragi, Sergei Anisimov, Masaaki Komatsu, Masahiro Fujii. USP10 inhibits the dopamine-induced reactive oxygen species-dependent apoptosis of neuronal cells by stimulating the antioxidant Nrf2 activity. Journal of Biological Chemistry. 2021. 298. 1. 101448-101448
  • Taichi Kakihana, Masahiko Takahashi, Yoshinori Katsuragi, Shun-Ichi Yamashita, Junya Sango, Tomotake Kanki, Osamu Onodera, Masahiro Fujii. The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43. iScience. 2021. 24. 7. 102733-102733
  • Naoyoshi Maeda, Akira Matsuda, Satoko Otsuguro, Masahiko Takahashi, Masahiro Fujii, Katsumi Maenaka. Antitumor Effect of Sugar-Modified Cytosine Nucleosides on Growth of Adult T-Cell Leukemia Cells in Mice. Vaccines. 2020. 8. 4. 658-658
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MISC (7):
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Professional career (1):
  • 博士(理学) (筑波大学)
Work history (4):
  • 2016/11/01 - 現在 Niigata University Graduate School of Medical and Dental Sciences Community Disease Control Infectious Disease Control and International Medicine Associate Professor
  • 2015/04/01 - 2016/10/31 Niigata University Graduate School of Medical and Dental Sciences Community Disease Control Infectious Disease Control and International Medicine Lecturer
  • 2007/04/01 - 2015/03/31 Niigata University Graduate School of Medical and Dental Sciences Community Disease Control Assistant Professor
  • 2004/04/01 - 2007/03/31 Niigata University Graduate School of Medical and Dental Sciences Assistant
Association Membership(s) (3):
日本癌学会 ,  The Japanese Society for Virology ,  THE JAPAN NEUROSCIENCE SOCIETY
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