Rchr
J-GLOBAL ID：200901059637615923
Update date: Oct. 07, 2024
Takebayashi Shin-ichiro
タケバヤシ シンイチロウ | Takebayashi Shin-ichiro
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://kyoin.mie-u.ac.jp/profile/2922.html
Research field (2)：
Applied biochemistry
, Molecular biology
Research keywords (5)：
Cellular senescence
, Epigenetics
, DNA replication
, Chromatin domain
, Chromosome
Research theme for competitive and other funds (11)：
- 2024 - 2027 栄養膜巨細胞に内在するゲノムコピー数調節原理の解明
- 2024 - 2026 Deciphering the design principles of the genome through the analysis of its potential instability
- 2022 - 2025 遺伝子の機能的発現を可能にするクロマチンドメインの構築原理解明
- 2021 - 2024 Elucidation of the construction principle of animal cell chromosomes and their control mechanism
- 2020 - 2022 非ゲノム複製の破綻がもたらすDNA損傷メカニズムの解明
- 2019 - 2022 Stability and flexibility of the DNA replication program revealed by single-cell DNA replication sequencing in vivo
- 2017 - 2020 A novel mechanism to regulate chronic inflammation through metabolic remodeling in obesity and senescence
- 2016 - 2018 染色体機能ドメイン制御の可塑性とその意義
- 2014 - 2016 Study on the antitumor mechanism of Rb-dependent mitochondrial metabolic remodeling
- 2003 - 2007 胚発生におけるゲノムDNAメチル化の機能と調節機構
- 1999 - 2001 動物細胞ゲノムの核内構造と遺伝子の機能的発現に関する研究
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Papers (42)：
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Saori Takahashi, Hirohisa Kyogoku, Takuya Hayakawa, Hisashi Miura, Asami Oji, Yoshiko Kondo, Shin-Ichiro Takebayashi, Tomoya S Kitajima, Ichiro Hiratani. Embryonic genome instability upon DNA replication timing program emergence. Nature. 2024
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Takuya Hayakawa, Asahi Yamamoto, Taiki Yoneda, Sakino Hori, Nanami Okochi, Kazuhiro Kagotani, Katsuzumi Okumura, Shin-Ichiro Takebayashi. Reorganization of the DNA replication landscape during adipogenesis is closely linked with adipogenic gene expression. Journal of cell science. 2023. 136. 2
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Megumi Sakamoto, Sakino Hori, Asahi Yamamoto, Taiki Yoneda, Kenji Kuriya, Shin-Ichiro Takebayashi. scRepli-Seq: A Powerful Tool to Study Replication Timing and Genome Instability. Cytogenetic and genome research. 2022. 162. 4. 161-170
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Shin-Ichiro Takebayashi, Tyrone Ryba, Kelsey Wimbish, Takuya Hayakawa, Morito Sakaue, Kenji Kuriya, Saori Takahashi, Shin Ogata, Ichiro Hiratani, Katsuzumi Okumura, et al. The Temporal Order of DNA Replication Shaped by Mammalian DNA Methyltransferases. Cells. 2021. 10. 2
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Takuya Hayakawa, Rino Suzuki, Kazuhiro Kagotani, Katsuzumi Okumura, Shin-Ichiro Takebayashi. Camptothecin-Induced Replication Stress Affects DNA Replication Profiling by E/L Repli-Seq. Cytogenetic and genome research. 2021. 161. 8-9. 437-444
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MISC (2)：
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FUJITA Naoyuki, TAKEBAYASHI Shin-ichiro, OKUMURA Katsuzumi, SAYA Hideyuki, NAKAO Mitsuyoshi. Transcriptional silencing of the genes by methyl-CpG binding protein PCM1 isoforms. 1998. 21. 225-225
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NOGAMI Masahiro, KOHDA Atsushi, TAKEBAYASHI Shin-ichiro, OKUMURA Katsuzumi, TAGUCHI Hiroshi, NAKAO Mitsuyoshi, IKEMURA Toshimichi. Intranuclear localization of SNRPN gene in HL60 cells. 1998. 21. 476-476
Education (3)：
- 1999 - 2002 Mie University Graduate School of Bioresources
- 1997 - 1999 Mie University Graduate School of Bioresources
- 1993 - 1997 Mie University Faculty of Bioresources
Professional career (1)：
Work history (9)：
- 2023/08 - 現在 Mie University Graduate School of Bioresources Professor
- 2017/05 - 現在 国立研究開発法人理化学研究所 客員研究員(兼任)
- 2019/03 - 2023/07 Mie University Graduate School of Bioresources Associate Professor
- 2014/04 - 2019/02 Mie University Graduate School of Medicine
- 2013/05 - 2014/03 Kumamoto University Priority Organization for Innovation and Excellence
- 2012/07 - 2013/04 Kumamoto University Institute of Molecular Embryology and Genetics
- 2007/10 - 2012/06 米国フロリダ州立大学 生物科学部門 ポストドクトラルフェロー
- 2002/04 - 2007/09 RIKEN
- 1999/04 - 2002/03 Japan Society for the Promotion of Science
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Association Membership(s) (3)：
日本エピジェネティクス研究会
, 日本農芸化学会
, 日本分子生物学会
