Rchr
J-GLOBAL ID:200901059716785281
Update date: Oct. 28, 2024
Tsumoto Kanta
ツモト カンタ | Tsumoto Kanta
Affiliation and department:
Job title:
教授
Research field (5):
Nanobioscience
, Functional biochemistry
, Biophysics
, Biochemistry
, Bio-, chemical, and soft-matter physics
Research keywords (23):
Cell-Derived Materials
, Liquid Liquid Phase Separation (LLPS)
, lipid bilayer membrane
, Micro-phase Separation
, Micro-phase segregation
, Aqueous Two-Phase Separation (ATPS)
, Aqeuous Two-Phase System (ATPS)
, giant liposome
, artificial cell
, artificial cell membrane
, baculovirus
, liposome
, GUV
, 膜蛋白質システム
, 高次構造転移
, 細胞サイズのリポソーム
, 長鎖DNA
, 生体高分子
, membrane protein systems
, transition of higher-order structure
, cell-sized liposome
, DNA chain
, biopolymer
Research theme for competitive and other funds (22):
- 2022 - 2026 Platform for analysis of biological vesicle contents by fusion with membranes suspended over microwells
- 2019 - 2022 Organization of artificial cells into an assembled model that can express orchestrated dynamic behavior through cell junction networks
- 2017 - 2021 Simultaneous production of monoclonal antibodies against multiple membrane proteins and their evaluations for the applications to therapeutic medicines
- 2018 - 2020 Artificial models for cytoplasm with gravity-sensitive properties
- 2016 - 2020 人工細胞システムによる細胞情報クロストークの実現と細胞動態解析
- 2015 - 2019 Artificial synapse formation by molecular bottom-up technology
- 2013 - 2017 Advanced hybridoma technology for selective generation of stereospecific monoclonal antibodies to GPCRs and its application
- 2013 - 2016 Analysis on signla transduction with membrane receptor-/ effector protein-reconsituted artificial cell systems
- 2011 - 2016 Real-World Modeling on the Hierarchical Dynamics of Living System
- 2012 - 2014 人工細胞系に構成した細胞膜受容体・細胞骨格複合ナノ装置の動作解析
- 2011 - 2012 Constitution of a signal pathway with a small number of protein components on cell-sized liposomes and the application for analysis of the ligand agents
- 2008 - 2009 人工細胞モデル構築のための膜蛋白質複合システム機能の再構成
- 2006 - 2007 巨大リポソーム膜における膜蛋白質複合システム機能の再構成
- 2006 - 巨大リポソームを基礎とする膜蛋白質複合モデルシステムの再構築
- 2006 - Developmental reconstitution of transmembrane protein multicomponent systems based on giant liposomes toward modeling artificial cells
- 2004 - 2005 サイズ非対称な脂質二分子膜融合の生物学的意義に関するモデル実験研究
- 1998 - 2005 DNAの高次構造と機能発現に関する研究
- 1998 - 2005 Study on correlation between higher-order structure and function of DNA
- 2004 - 2004 DNAの折り畳み相転移と遺伝子群の発現制御
- 2003 - 2003 DNAの折り畳み相転移と遺伝子群の発現制御
- 2000 - 細胞サイズリポソームの特性解析とマイクロリアクター化
- 2000 - Study on properties of cell-sized liposomes encapsulating biochemical/biophysical processes
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Papers (61):
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Misako Nishigami, Yuki Uno, Kanta Tsumoto. Microscopic Observation of Membrane Fusion between Giant Liposomes and Baculovirus Budded Viruses Activated by the Release of a Caged Proton. Membranes. 2023. 13. 5. 507-507
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Hiroki Sakuta, Naoki Nakatani, Takayuki Torisawa, Yutaka Sumino, Kanta Tsumoto, Kazuhiro Oiwa, Kenichi Yoshikawa. Self-emergent vortex flow of microtubule and kinesin in cell-sized droplets under water/water phase separation. Communications chemistry. 2023. 6. 1. 80-80
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Kingo TAKIGUCHI, Hiroki SAKUTA, Masahito HAYASHI, Tatsuyuki WAIZUMI, Kanta TSUMOTO, Kenichi YOSHIKAWA. Behavior of Biopolymers, Cytoskeleton, DNA, and Phospholipids, that Exert Self-organization, Shown in the Liquid-Liquid Phase Separation. Seibutsu Butsuri. 2023. 63. 1. 5-11
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Kento Sakashita, Kanta Tsumoto, Masahiro Tomita. Advanced hybridoma technology for selective production of high-affinity monoclonal antibodies through B-cell receptors. Journal of Immunological Methods. 2022. 511. 113384-113384
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Marcos Masukawa, Yusuke Sato, Fujio Yu, Kanta Tsumoto, Kenichi Yoshikawa, Masahiro Takinoue. Water-in-water droplets selectively uptake self-assembled DNA nano/microstructures: a versatile method for purification in DNA nanotechnology. ChemBioChem. 2022. 23. 17. e202200240
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MISC (28):
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Pasquale Stano, Kanta Tsumoto. Membranous and Membraneless Interfaces-Origins of Artificial Cellular Complexity. Life. 2023
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湊元幹太, ジンチェンコ アナトーリ. 42. 細胞様構造と相分離:モデル実験によるアプローチ. 現代化学・増刊46 相分離生物学の全貌(白木賢太郎 編). 2020
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湊元幹太. 水性ミクロ相分離:バイオケミカルリアクターへの利用. 化学工業. 2020. 71. 4. 242-246
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Y. Hoda, T. Fujimoto, K. Yoshikawa, K. Tsumoto. Specific localization of living cells in water/water microdroplets toward the spontaneous generation of 3D cell-assembly: Experiments with red blood cells and NAMRU mouse mammary gland epithelial cells. 2018 International Symposium on Micro-NanoMechatronics and Human Science (MHS). 2018
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湊元 幹太. ロバストな細胞膜マーカ解析探針としての人工細胞脂質膜ナノビーズ. 豊田研究報告. 2018. 71. 170-171
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Patents (7):
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細胞接着基板及びその製造方法
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脂質膜デバイスの製造方法
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ウイルス感染能評価用基板及びウイルス感染能評価方法
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診断用組換えプロテオリポソームの作製法
-
リポソーム製造装置
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Books (1):
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わかる理工系のための化学
共立出版 2012 ISBN:9784320044005
Lectures and oral presentations (27):
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Development of a microwell device for electrofusion of cells with different sizes
(電気化学秋季大会講演要旨集(CD-ROM) 2021)
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DEVELOPMENT OF A MICROWELL DEVICE FOR ELECTROFUSION OF CELLS WITH DIFFERENT SIZES
(Chemical Sensors 2021)
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遺伝子発現におけるポリアミンの促進と阻害の二面性
(日本ポリアミン学会年会プログラム及び抄録集 2018)
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Spontaneous Compartmentalization Selectively Entraps Intracellular Proteins under a Macromolecular Crowding Condition: Self-Emergence of Cell-Like Structure.
(MOLECULAR BIOLOGY OF THE CELL 2016)
-
Transition of Higher-Order Structure of DNA with Polyamines Causes Marked Change on Gene-Expression
(MOLECULAR BIOLOGY OF THE CELL 2016)
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Education (4):
- - 2002 Nagoya University
- - 2000 Nagoya University
- - 1998 The University of Tokyo Faculty of Science
- - 1996 The University of Tokyo Faculty of Science Dept. of Biophysics and Biochemistry
Professional career (2):
- Master of Philosophy (Nagoya University)
- Doctor of Philosophy (Nagoya University)
Work history (5):
- 2020/12 - 現在 Mie University Graduate School of Engineering Professor
- 2015/11 - 2020/11 Mie University Graduate School of Engineering Associate Professor
- 2008/02 - 2015/10 Mie University Graduate School of Engineering Lecturer
- 2007/04 - 2008/01 Mie University Graduate School of Engineering Assistant Professor
- 2002/12 - 2007/03 Mie University Faculty of Engineering Research Associate
Committee career (8):
- 2021 - 現在 日本生物工学会中部支部 企画幹事
- 2021 - 現在 日本化学会東海支部 化学教育協議会委員
- 2019/05 - 現在 日本化学会コロイドおよび界面化学部会 事業企画委員会委員
- 2020 - 2023 日本生化学会 代議員
- 2021 - 2022 日本生物工学会中部支部 支部役員 支部幹事(庶務)
- 2014/09 - 2016/08 日本生化学会 中部支部幹事(第2グループ)
- 2013/03 - 2015/02 日本化学会 代表正会員(東海支部)
- 2012/01 - 2013/12 日本生物物理学会 「生物物理」会誌編集委員会委員
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Association Membership(s) (7):
The Society for Biotechnology, Japan
, Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA)
, The Society of Nano Science and Technology
, American Chemical Society
, The Chemical Society of Japan
, The Japanese Biochemical Society
, The Biophysical Society of Japan
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