Rchr
J-GLOBAL ID:200901060077841955
Update date: Sep. 05, 2024
Numoto Nobutaka
ヌモト ノブタカ | Numoto Nobutaka
Affiliation and department:
Job title:
Special-Appointment Associate Professor
Research field (1):
Structural biochemistry
Research theme for competitive and other funds (7):
Papers (60):
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Mutsumi Yoshida, Yuya Hanazono, Nobutaka Numoto, Satoshi Nagao, Saaya Yabuno, Yumi Kitagawa, Hiroshi Sekiguchi, Nobutoshi Ito, Takachika Azuma, Masayuki Oda. Affinity-matured antibody with a disulfide bond in H-CDR3 loop. Archives of Biochemistry and Biophysics. 2024. 758. 110068-110068
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Chizuru Akatsu, Takahiro Tsuneshige, Nobutaka Numoto, Wang Long, Toshio Uchiumi, Yoshikatsu Kaneko, Masatake Asano, Nobutoshi Ito, Takeshi Tsubata. CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody. Journal of autoimmunity. 2024. 146. 103245-103245
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Gert-Jan Bekker, Nobutaka Numoto, Maki Kawasaki, Takahiro Hayashi, Saaya Yabuno, Yuko Kozono, Takeyuki Shimizu, Haruo Kozono, Nobutoshi Ito, Masayuki Oda, et al. Elucidation of binding mechanism, affinity and complex structure between mWT1 tumor-associated antigen peptide and HLA-A*24:02. Protein Science. 2023
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Akiko Kamegawa, Shota Suzuki, Hiroshi Suzuki, Kouki Nishikawa, Nobutaka Numoto, Yoshinori Fujiyoshi. Structural analysis of the water channel AQP2 by single-particle cryo-EM. Journal of structural biology. 2023. 215. 3. 107984-107984
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Daisuke Kozai, Nobutaka Numoto, Kouki Nishikawa, Akiko Kamegawa, Shohei Kawasaki, Yoko Hiroaki, Katsumasa Irie, Atsunori Oshima, Hiroyuki Hanzawa, Kousei Shimada, et al. Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit. Journal of molecular biology. 2023. 435. 10. 168049-168049
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MISC (46):
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Nobutaka Numoto. Structure Determination from Protein Crystal Clusters by Fully Automatic Data Collection. Journal of the Crystallographic Society of Japan. 2021. 63. 3
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Oda M, Numoto N, Bekker GJ, Kamiya N, Kawai F. Cutinases from thermophilic bacteria (actinomycetes): from identification to functional & structural characterization. Methods Enzymol. 2021. 159-185
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Numoto N, Kamiya N, Kawai F, Oda M. Crystal Structures of Polyethylene Terephthalate-Degrading Enzyme Cut190 in Substrate-Bound States Reveal the Enzymatic Reaction Cycle Accelerated by Calcium Ion. ACS Symposium Series "Green Polymer Chemistry and Sustainability.". 2021
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清水 奏, 宮下 由里奈, 松尾 直也, 中野 祥吾, 伊藤 創平, 沼本 修孝, 伊倉 貞吉, 伊藤 暢聡, 加来田 博貴, 常盤 広明. hRXRαリガンドCBt-PMNのパーシャルアゴニスト活性の起源は何か?. 日本薬学会年会要旨集. 2018. 138年会. 2. 111-111
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沼本修孝, 細江雄飛, 稲葉理美, 稲葉理美, 小川修平, 森井尚之, 安部良, 織田昌幸, 伊藤暢聡. シグナル伝達分子Grb2 SH2ドメインとCD28由来ペプチド複合体の水素原子の可視化を目指した高分解能結晶構造解析. メディシナルケミストリーシンポジウム講演要旨集. 2018. 36th
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Books (1):
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Crystallography in Japan (II)
Crystallographic Society of Japan 2014 ISBN:9784990386122
Lectures and oral presentations (71):
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Molecular mechanism of self-antigen recognition by the ligand binding domain of B cell inhibitory co-receptor CD72
(25th Congress and General Assembly of the International Union of Crystallography 2021)
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A user review of automatic and remote measurement at SPring-8
(59th SPring-8 Advanced Utilization Technology Workshop / IPR Seminar 2021)
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A user review of automatic and remote measurement at SPring-8
(Webinar on Annual Meeting 2020 and General Assembly of Crystallographic Society of Japan 2020)
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Structure determination from cluster crystals of an inhibitory B cell co-receptor CD72
(Annual Meeting 2020 and General Assembly of Crystallographic Society of Japan 2020)
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Structural and characteristics analysis of intracellular signal transduction protein PI3K SH2
(The 56th Japan Conference Calorimetry and Thermal Analysis 2020)
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Education (3):
- 2001 - 2004 Kyoto University Graduate School, Division of Natural Science
- 1999 - 2001 Kyoto University Graduate School, Division of Natural Science
- 1995 - 1999 Kyoto University Faculty of Science
Professional career (1):
Work history (8):
- 2024/01 - 現在 Okayama University International Center for Structural Biology, Research Institute for Interdisciplinary Science Special-Appointment Associate Professor
- 2021/06 - 2023/12 Tokyo Medical and Dental University Medical Research Institute Advanced Molecular Medicine Structural Biology Associate Professor
- 2012/10/01 - 2021/05/31 Tokyo Medical and Dental University Medical Research Institute Advanced Molecular Medicine Structural Biology Assistant Professor
- 2012/10 - 2021/05 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Life Science and Technology Life Science and Technology Structural Biology Assistant Professor
- 2010/02/01 - 2012/09/30 Kyoto University Research Reactor Institute
- 2008/04/01 - 2010/01/31 Kanazawa University Institute of Science and Engineering, Faculty of Natural System
- 2007/04/01 - 2008/03/31 Kanazawa University Faculty of Science, Department of Biology
- 2004/04/01 - 2007/03/31 Kyoto University Graduate School of Science, Division of Chemistry
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Committee career (6):
Awards (3):
- 2017/03 - 平成28年度難治疾患研究所最優秀論文賞 CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous Toll-like receptor 7 ligand Sm/RNP
- 2011/09 - 日本磁気科学会 日本磁気科学会研究奨励賞 磁気力場中でのタンパク質結晶化
- 2010/12 - 日本結晶学会 日本結晶学会進歩賞 巨大ヘモグロビンとV型ATPaseの構造と機能に関する結晶学的研究
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