Fujii Hirofumi

フジイヒロフミ | Fujii Hirofumi

Affiliation and department：
Job title： Executive Director

Research field (1)： Radiology

Research theme for competitive and other funds (25)：

2019 - 2023 Development of imaging technologies of metastatic lesions inside sentinel lymph nodes by visualizing of immune reactions
2019 - 2023 Three Dimensional Tracking of DDS Nano Carrier by OTN-NIR Fluorescence
2018 - 2022 進行固形がんの治癒をも可能にする革新的内用放射線治療法/セラノスティックスの創成
2017 - 2020 Development of radiotheranostics agent using Fab fragment of anti-regulatory T cells
2016 - 2019 Surrogate imaging of micrometastases in sentinel lymph nodes based on immune reactions

2015 - 2018 Theranostic study for neck micro-metastasis

2015 - 2018 Radionuclide-carrying liposomes with both high tumor accumulation and rapid background clearance

2013 - 2017 In vivo visualization of small metastatic lesion in sentinel lymph node using immunological methods

2013 - 2017 Development of computer-aided diagnosis software for assessing tumor response to molecular targeted therapy by using a novel machine learning technique named CARTA

2012 - 2015 Affibody probes for near-infrared fluorescence imaging of cancer cells in sentinel lymph nodes

2012 - 2015 Development of theranostic liposomes enabling the treatment of intractable cancer

2011 - 2013 複合分子イメージング技術によるがん微小環境ネットワークのイン・ビボ可視化

2011 - 2013 Establishment and validation of corrected SUVmax correlated with prognosis following stereotactic body radiotherapy for non-small cell lung cancer

2010 - 2012 Molecular imaging for the evaluation of chemosensitivity by a novel hyperpolarized magnetic resonance imaging

2010 - 2012 Fusion imaging for sentinel node navigation high-precision radiotherapy

2007 - 2009 The imaging of micrometastases in lymph nodes by super-high-resolution magnetic resonance imaging in combination with super-high-sensitivity imaging.

2004 - 2005 Digital Watermark method suitable for teleradiology in aspect of watermark tolerance and image degradation

2003 - 2004 Three-dimensional fusion imaging of radioscintigraphy and CT for minimal invasive treatment of malignancies.

2002 - 2003 Development of the digital securewatermark for teleradiology environment

2001 - 2003 Development of novel minimally invasive surgery for solid tumors using sentinel node navigation

2001 - 2002 In vivo diagnostic method of metastasis in the sentinel lymph node using tumor-avid radionuclide

2000 - 2001 Image processing for a Portable Image Viewer: Optimization of Gray-scale manipulation

1997 - 1998 抗癌剤耐性予測のための核医学的手法の開発

1995 - 1995 腫瘍細胞の分化誘導と放射線療法の併用による治療効果改善の実験的検討

1992 - 1992 ニューラルネットワークを用いた肝臓癌の進行度の定量化に関する研究

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Papers (102)：

梅田泉, 藤井博史. Simultaneous visualization of multiple radionuclides in vivo. Nature biomedical engineering. 2022. 2022
梅田泉, 藤井博史. 治療用核種186Reと脂溶性配位子との錯体形成に関する検討 99mTcとの比較. 日本癌学会総会記事. 2021. 80回. [P19-5]
梅田泉, 藤井博史. 新規radio-theranostic製剤としての111In/90Y-リポソーム. 日本癌学会総会記事. 2020. 79回. PJ17-6
Toshihiro Furuta, Masayuki Yamaguchi, Manabu Minami, Osamu Abe, Hirofumi Fujii. Treatment margins in radiotherapy for liver tumors visualized as T2*-hypointense areas on SPIO-enhanced MRI at 9.4 T. MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. 2020
森田敬裕, 藤井博史, 伊藤公輝, 楠本昌彦. 肺癌加療中に生じた右上肢・両下肢麻痺精査でFDG PET/MRIが診断に有用であった1症例. 核医学. 2020. 57. 1. 35-35

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MISC (423)：

相良裕亮, 井上一雅, 夜久英樹, 大澤阿紋, 森田敬裕, 檜山貴志, 藤井博史. FDG-PET/CT検査における体格に基づく新たな画質評価指標の検討. 日本放射線技術学会総会学術大会予稿集. 2022. 78回. 159-159
梅田泉, 永田みどり, 天崎茜, 大貫和信, 柳下淳, 武田伸一郎, 桂川美穂, 藤井博史, 高橋忠幸. 111In-DOTA/90Y-DOTA封入リポソームによるradio-theranosticsの試み. 日本薬学会年会要旨集. 2021. 141年会. 28P02-067
大貫和信, 山口雅之, 藤井博史. センチネルリンパ節内転移診断と予後予測に向けたイメージング技術の開発. JSMI Report. 2018. 11. 2. 131-131
梅田泉, 濱道修生, 藤井博史. がん選択的集積を可能にする放射性核種錯体封入リポソームヒト腫瘍皮下移植モデルでの検討. 日本DDS学会学術集会プログラム予稿集. 2017. 33回. 199-199
濱道修生, 梅田泉, 藤井博史, 伊藤憲, 浅野誠, 堀優作, 岩田正夫, 松井順二, 船橋泰博. 放射性核種封入リポソームを用いたリポソーム化抗癌剤の薬効予測技術の開発. 核医学. 2017. 54. 1. 540-540

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Education (2)：

- 1987 Keio University School of Medicine Depertment of Medicine
- 1987 Keio University Faculty of Medicine

Professional career (1)：

医学 (慶應義塾大学)

Work history (9)：

2002/04 - 2004/12 Keio University, School of Medicine Department of Radiology Assistant Professor
1996 - 2002 大学助手(医学部放射線科学)
2001 - 2001 大学病院診療科医長(放射線科, 放射線治療・核医学科)(外来担当)
2001 - - 大学病院診療科医長(放射線科, 放射線治療・核医学科)(外来担当)
1993 - 1997 大学医学部助手(放射線科学)

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Awards (4)：

2001 - 三四会奨励賞
2001 - 第40回日本核医学会賞
2000 - 第38回日本癌治療学会優秀賞
1999 - 第4回日本核医学会機関誌Annals of Nuclear Medicine最優秀論文賞

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