Research theme for competitive and other funds (21)：
2014 - 2018 Whole-body functional analysis of the BAF complex in the visualized zebrafish nervous system using genome editing
2012 - 2015 The barrier structure of glial limitans in the hippocampal fissureis is broken in the normal mouse, but maintained in the reeler.
2012 - 2015 Studies on the neuron-specific transcriptional regulator Dpf1 using transgenic zebrafish expressing neuronal tracers
2008 - 2011 Mechanism of laminar formation of cerebral cortex and layer-specific neural circuits
2009 - 2010 海馬裂における軟膜・グリア性境界膜の生理的分解と維持
2006 - 2007 Astudy on reulatory mechanisms of glial basement membrane formation and neuronal migration using a fish model
2006 - 2007 上丘の層形成と視覚性神経回路形成に関するリーリンシグナル伝達系の機能
2005 - 2007 Mechanisms of Layer Formation of Cerebral Neocortex and Layer-specific Neural Circuits
2004 - 2005 Research on mechanisms of development and collapse of the pial and glial limiting membranes, which comprise the cerebrospinal fluid-brain barrier
2001 - 2002 嗅球のシナプス回路形成におけるReelinシグナル系の役割の解明
2000 - 2001 アスペルギルス細胞核の移動とニューロン細胞移動の相似性の証明
1999 - 2001 Development of gene therapy by the retrograde axonal transport of adenovirus into the reeler mouse
1999 - 1999 リーラー類似動物大脳皮質運動野の神経回路網形成
1997 - 1999 Abnormal migration of the motor trigeminal, facial, and ambiguus nuclei neurons of the SRK rat
1998 - 1998 リーラー類似動物(ヨタリ、SRKラット)の大脳皮質運動野の神経回路網
1997 - 1998 ロドプシンキナーゼの特異的基質認識を担う構造要因の検索
1995 - 1998 MOLECULAR MECHANISM OF SIGNAL TRANSDUCTION IN VISUAL AND NEURAL SYSTEM OF ASCIDIAN BRAIN
1996 - 1996 光情報伝達における受容体-Gタンパク質間の相互作用のリアルタイム測定
1995 - 1995 網膜における代謝型グルタミン酸受容体-G蛋白質共役の解析
1994 - 1994 光受容体と共役する複数のG蛋白質;それらの相互作用は如何に調節されているか
1993 - 1994 MOLECULAR MECHANISM OF HYPERPOLARIZATION OF ON-BIPOLAR CELLS IN RETINA
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Papers (38)：
Shintaro Yamada, Toshiyuki Ko, Masamichi Ito, Tatsuro Sassa, Seitaro Nomura, Hiromichi Okuma, Mayuko Sato, Tsuyoshi Imasaki, Satoshi Kikkawa, Bo Zhang, et al. TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy. Science Advances. 2023. 9. 15. eade7047
Hiromichi Okuma, Yumiko Saijo-Hamano, Hiroshi Yamada, Aalaa Alrahman Sherif, Emi Hashizaki, Naoki Sakai, Takaaki Kato, Tsuyoshi Imasaki, Satoshi Kikkawa, Eriko Nitta, et al. Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I. Genes to Cells. 2023
Shinya Taguchi, Juri Nakano, Tsuyoshi Imasaki, Tomoki Kita, Yumiko Saijo-Hamano, Naoki Sakai, Hideki Shigematsu, Hiromichi Okuma, Takahiro Shimizu, Eriko Nitta, et al. Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex. eLife. 2022. 11
Tsuyoshi Imasaki, Satoshi Kikkawa, Shinsuke Niwa, Yumiko Saijo-Hamano, Hideki Shigematsu, Kazuhiro Aoyama, Kaoru Mitsuoka, Takahiro Shimizu, Mari Aoki, Ayako Sakamoto, et al. CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation. eLife. 2022. 11
Shinya Taguchi, Juri Nakano, Tsuyoshi Imasaki, Tomoki Kita, Yumiko Saijo-Hamano, Naoki Sakai, Hideki Shigematsu, Hiromichi Okuma, Takahiro Shimizu, Eriko Nitta, et al. Structural model of microtubule dynamics inhibition by Kinesin-4 from the crystal structure of KLP-12 -tubulin complex. bioRxiv. 2022
A possible novel mode of action for Dab1 in modulation of neuronal migration of neocortical neurons
(“Neuroscience 2016” Society for Neuroscience 46th annual meeting 2016)
New functional role of Dab1 protein in neuronal migration of the cerebral cortex
(The 121st Annual Meeting of the Japanese Association of Anatomists 2016)
Preparation of reelin-KO zebra fish with an use of CRISPER-Cas9 system
(The 121st Annual Meeting of the Japanese Association of Anatomists 2016)
