Takechi Shinji

タケチシンジ | Takechi Shinji

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.ph.sojo-u.ac.jp/~stakechi/HygienChem090727/index.html

Research field (6)： Structural biochemistry , Molecular biology , Pharmaceuticals - health and biochemistry , Molecular biology , Environmental effects of chemicals , Environmental effects of radiation

Research keywords (16)：神経変性疾患 , エピジェネティクス , DNA複製 , ヒストン , クロマチン構造 , 遺伝子発現 , 細胞増殖 , 転写制御 , アミノ酸配列 , ヒストン修飾酵素 , 発現制御 , CATアッセイ , 化学物質による遺伝情報複製・発現制御の攪乱機構の解明 , Cellar Stress , Radical Generation , Glycation

Research theme for competitive and other funds (5)：

2012 - 2015 糖化反応物による生活習慣病発症機構解明と高感度診断法構築のための基盤的研究
2001 - 2003 Study on the regulatory mechanism for immunoglobulin expression through histone acetylation
1997 - 1998 ヒストンアセチルトランスフェラーゼによる染色体構造変化と遺伝子発現調節の解明
1996 - 1996 Bリンパ細胞株のヒストン欠失変異にみられる生物学的諸性質の解明
Study on Regulation of Histone Gene Experssion

Papers (48)：

Yuu Miyauchi, Ken Kurohara, Akane Kimura, Madoka Esaki, Keiko Fujimoto, Yuko Hirota, Shinji Takechi, Peter I. Mackenzie, Yuji Ishii, Yoshitaka Tanaka. The carboxyl-terminal di-lysine motif is essential for catalytic activity of UDP-glucuronosyltransferase 1A9. Drug Metabolism and Pharmacokinetics. 2020. 35. 5. 466-474
Madoka Esaki, Takumi Ishida, Yuu Miyauchi, Shinji Takechi. The effect of dihydropyrazines on lipopolysaccharide-stimulated human hepatoma HepG2 cells via regulating the TLR4-MyD88-mediated NF-κB signaling pathway. The Journal of Toxicological Sciences. 2020. 45. 7. 401-409
Ishida T, Takechi S. β-Naphthoflavone , an exogenous ligand of aryl hydrocarbon receptor , disrupts zinc homeostasis in human hepatoma. J. Toxicol. Sci. 2019. 44. 10. 711-720
宋穎霞, 藤本景子, 黒瀬厚, 石田卓巳, 古賀貴之, 李任時, 武田知起, 武知進士, 山田英之, 田中嘉孝, et al. 雌マウス肝臓におけるセレン結合性タンパク質 (SelenBP)の発現と 2,3,7,8- tetrachlorodibenzo-p-dioxin 被誘導性: SelenBP1 欠損動物を用いた検討. 福岡医学雑誌. 2019. 110. 2. 128-132
Jumpei Togawa, Takekazu Ohi, Jun-Hui Yuan, Hiroshi Takashima, Hirokazu Furuya, Shinji Takechi, Junko Fujitake, Saki Hayashi, Hiroyuki Ishiura, Hiroya Naruse, et al. Atypical Familial Amyotrophic Lateral Sclerosis with Slowly Progressing Lower Extremities-predominant Late-onset Muscular Weakness and Atrophy. Internal medicine (Tokyo, Japan). 2019. 58. 13. 1851-1858

ｍore...

MISC (3)：

Education (4)：

- 1991 Osaka University
- 1991 Osaka University
- 1986 Osaka University
- 1986 Osaka University

Professional career (1)：

(BLANK)

Work history (3)：

2011/04 - 現在 Sojo University Faculty of Pharmaceutical Sciences
2005/04 - 2011/03 Sojo University Faculty of Pharmaceutical Sciences
1991/04 - 2005/03 University of Miyazaki Faculty of Medicine

Association Membership(s) (4)：

日本衛生学会 , 日本薬学会 , 日本生化学会 , 日本分子生物学会

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