Yasuhira Shinji

ヤスヒラシンジ | Yasuhira Shinji

Affiliation and department：

Research field (3)： Cell biology , Molecular biology , Genetics

Research keywords (7)： signal transduction , malignant melanoma , 細胞分裂 , cell cycle checkpoint , 疾患関連遺伝子 , DNA repair , 分子進化

Research theme for competitive and other funds (13)：

2021 - 2024 Double negative regulation of ERK activity by dual-specificity phosphatases and its role in melanomagenesis
2020 - 2023 Research on signal transduction inhibitors and novel molecules with synthetic lethal effects in melanoma
2013 - 2016 Mechanism for natural resistance of melanoma cells against anti-tubulin drugs
2013 - 2016 Effect of RhoGDI2 expression on progression of colon cancer
2003 - 2003 LET増加に伴うRBEの上昇はDNA二重鎖切断のエラー修復で説明できるか

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Papers (44)：

Tsuyoshi Inoue, Daisuke Watabe, Maiko Furukawa, Maki Goto, Hirofumi Kamada, Yuri Sato, Nobuyuki Arakawa, Shinpei Miura, Toshiki Sato, Shinji Yasuhira, et al. Prevalence and risk factors for onychomycosis in acute care dermatology wards. The Journal of dermatology. 2024. 51. 8. 1079-1082
Takashi Akihiro, Ryo Yasui, Shinji Yasuhira, Ken-ichi Matsumoto, Yasuhiro Tanaka, Yasuhiro Matsuo, Hidehisa Shimizu, Takashi Matsuzaki, Shingo Matsumoto, Keisuke Yoshikiyo, et al. Tropomyosin micelles are the major components contributing to the white colour of boiled shellfish soups. Scientific Reports. 2022. 12. 1. 15253-15253
Hirofumi Kamada, Shinji Yasuhira, Masahiko Shibazaki, Hiroo Amano, Chihaya Maesawa. DUSP4 Inactivation Leads to Reduced Extracellular Signal-Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells. Journal of Investigative Dermatology. 2022. 142. 9. 2499-2507.e6
前沢千早, 安平進士, 柴崎晶彦, 渡辺彩乃, 角田加奈子, 三浦慎平, 天野博雄, 西谷匡央. 悪性黒色腫の生物学的特性の原因となる遺伝子変異(Mutations predisposing to melanoma: Implications for tumor behavior). 岩手医学雑誌. 2021. 72. Suppl. 233-241
村上暁子, 安平進士, 間山寿代, 三浦廣行, 佐藤和朗, 前沢千早. 全エクソーム解析を用いたヒトにおける歯の先天欠如に関わる遺伝要因の探索. 岩手医科大学歯学雑誌. 2020. 45. 1. 13-22

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MISC (17)：

A. Okubo, N. Arakawa, S. Yasuhira, M. Shibazaki, T. Akasaka, H. Amano, C. Maesawa. Clarification of cytotoxic mechanism in rhododendrol Verification of correlation between NQO1 polymorphism and incidence of RD-induced leukoderma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017. 137. 10. S233-S233
A. Okubo, M. Nishiya, S. Yasuhira, C. Maesawa, T. Masuda. NAD(P)H dehydrogenase, quinone 1 (NQO1) protects melanin-producing cells from cytotoxicity of rhododendrol. VIRCHOWS ARCHIV. 2016. 469. S141-S141
S. Miura, C. Maesawa, M. Shibazaki, S. Yasuhira, K. Syuya, K. Tsunoda, F. Maeda, K. Takahashi, T. Masuda, T. Akasaka. Immunohistochemistry for histone H3 lysine 9 methyltransferase and demethylase proteins in human malignant melanomas. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2013. 133. S228-S228
土居崇, 張秋梅, 田野恵三, 安平進士, 米井脩治. 分裂酵母S.pombeにおけるGOシステムに関与するDNAグリコシラーゼの同定. 日本放射線影響学会第45回大会. 2002
田野恵三, 安平進士, 園田英一郎, 武田俊一, 内海博司. ニワトリ DT40細胞を用いた相同組み換え阻害剤のスクリーニングの試み. 日本放射線影響学会第45回大会. 2002

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Education (5)：

1990 - 1993 Tohoku University
- 1993 The University of Tokyo
- 1993 The University of Tokyo Graduate School, Division of Science
- 1988 The University of Tokyo Faculty of Science Department of Biological Sciences
- 1988 The University of Tokyo Faculty of Science

Professional career (1)：

Work history (4)：

Association Membership(s) (2)：

酵母遺伝学フォーラム , 日本分子生物学会

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