Hirooka Kazutake

ヒロオカカズタケ | Hirooka Kazutake

Affiliation and department：
Job title： professor

Research field (2)： Applied biochemistry , Functional biochemistry

Research keywords (3)：タンパク質工学 , 遺伝子発現 , 枯草菌

Research theme for competitive and other funds (11)：

2020 - 2023 Protein expression system inducible by low-toxic substances in Bacillus subtilis
2015 - 2018 Pioneer research of transcription network of stringent control in Bacillus subtilis and its application
2011 - 2014 Elucidation of transcription network of stringent control in Bacillus subtilis and its application
2010 - 2013 Multiple transcriptional regulatory systems of Bacillus subtilis, in response to plant-derived aromatic compounds
2008 - 2009 枯草菌炭素代謝制御ネットワークの物質産生系への有効活用

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Papers (40)：

Ami Koreeda, Rina Taguchi, Kanon Miyamoto, Yuna Kuwahara, Kazutake Hirooka. Protein expression systems combining a flavonoid-inducible promoter and T7 RNA polymerase in Bacillus subtilis. Bioscience, Biotechnology, and Biochemistry. 2023. 87. 9. 1017-1028
Kazutake Hirooka. RhgKL and CcpA directly regulate the rhiLFGN-rhgR-yesTUV operon involved in the metabolism of rhamnogalacturonan type I in Bacillus subtilis. Bioscience, Biotechnology, and Biochemistry. 2022. 86. 10. 1383-1397
Hiroshi Matsuoka, Miyu Katayama, Ami Ohishi, Kaoruko Miya, Riki Tokunaga, Sou Kobayashi, Yuya Nishimoto, Kazutake Hirooka, Akiho Shima, Akihiro Michihara. Orphan Nuclear Receptor RORα Regulates Enzymatic Metabolism of Cerebral 24S-Hydroxycholesterol through CYP39A1 Intronic Response Element Activation. International journal of molecular sciences. 2020. 21. 9
Hirooka K, Shioda S, Okada M. Identification of critical residues for the catalytic activity of ComQ, a Bacillus prenylation enzyme for quorum sensing, by using a simple bioassay system. Biosci Biotechnol Biochem. 2020. 84. 2. 347-357
Hirooka K, Tamano, A. Bacillus subtilis highly efficient protein expression systems that are chromosomally integrated and controllable by glucose and rhamnose. Biosci Biotechnol Biochem. 2018. 82. 11. 1942-54

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MISC (3)：

Fujita, Y, Tojo, S, Hirooka. K. Regulation of gene expression: Stringent transcription control of Escherichia coli and Bacillus subtilis. Escherichia coli and Bacillus subtilis: The Frontier of Molecular Microbiology, Revisited, 2012, Research Signpost, India. 2012. 179-196
東條繁郎, 広岡和丈, 藤田泰太郎. 枯草菌Bacillus subtilisの胞子形成トリガーへの正の緊縮転写制御の関与. 福山大学生命工学部研究年報. 2012. 11. 1-20
Fujita, Y, Miwa, Y, Tojo, S, Hirooka, K. Carbon catabolite control and metabolic networks mediated by the CcpA protein in Bacillus subtilis. Global Regulatory Networks in Bacillus subtilis, Transworld Research Network, India. 2007. 91-110

Lectures and oral presentations (8)：

2Ga03 Conversion of recognition specificity of Bacillus subtilis YxaF transcriptional regulator toward flavonids
(2008)
Characterization of isopentenyl diphosphate isomerase from Thermococcus kodakaraensis KOD1
(2003)
Temperature-dependence of structure and activity of prenyltransferase from Thermococcus kodakaraensis KOD1
(2003)
669 Characterization of prenyltransferase from Thermococcus kodakaraensis KOD1
(2002)
572 Characterization of the production activity of cis-rubber in Periploca sepium bunge
(2002)

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Professional career (1)：

Awards (2)：

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