Research keywords (13)：
Castleman disease
, targeting therapy
, Flt3
, c-Kit
, AML
, leukemia
, receptor tyrosine kinase
, targeting therapy
, c-Kit
, Flt3
, AML
, leukemia
, receptor tyrosine kinase
- 2017 - 2020 厚生労働科学研究費 補助金難治性疾患等政策研究事業「非癌、慢性炎症性リンパ節・骨髄異常を示すキャッスルマン病、TAFRO症候群その類縁疾患の診断基準、重症度分類の改正、診断・治療のガイドラインの策定に関する調査研究」
- 2016 - 2019 The impact of iron overload on immune function
- 2013 - 2016 Dendritic cell differentiation from myeloid neoplasm
- 2013 - 2016 The analysis of bone marrow microenvironment in myelodysplastic syndrome using patient-derived iPS cells
- 2013 - 2016 Analysis of the functions of anti-apoptotic molecule, Anamorsin -the roles in hematopoiesis and cellular iron metabolism-
- 2010 - 2012 Analysis of weak points in oncogenic tyrosine kinase-dependent growth
- 2010 - 2012 Analysis of functions of anamorsin, an anti-apoptotic molecule, in hematopoiesis
- 2010 - 2011 Analysis of leukemogenic transgenic mice generated by tetraploid embryonic complementation method using Tet-off system.
- 2009 - 2011 Energy metabolism in the growth and differentiation of hematopoietic stem/ progentor cells
- 2009 - 2011 THE EVALUATION FOR THE MANAGEMENT CABABILITY OF A UNIVERSITY HOSPITAL AS A DRIVEN SYSTEM OF THE SOCIAL MEDICAL SUPPLY CHAIN~TIME AND MOTION STUDY BASED APPROACH
- 2008 - 2010 Roles of leukemogenic oncogenes in the regulation of metabolism, growth, and differentiation of hematopoietic stem cells
- 2007 - 2008 STIMを中心とした細胞内カルシウム調節機構とサイトカインシグナル
- 2007 - 2008 Clarification of functions of Anamorsin, anti-apoptotic molecule, and its roles in malignant lymphomas
- 2006 - 2007 造血細胞における細胞老化克服遺伝子の単離と機能解析
- 2006 - 2007 The function of Sir2 in proliferation and aging of hematopoietic cells
- 2006 - 2007 Novel signal transduction pathways in constitutive active mutants of receptor tyrosine kianses
- 2006 - 2007 Synthetic Analysis on the mechanisms of survival and differentiation of hematopoietic cells
- 2006 - 2007 新規Gene-Trap法による多段階の白血病発症に関わる遺伝子単離の試み
- 2005 - 2006 Clarification of mechanism of anamorsin, anti-apoptotic molecule
- 2005 - 2005 Notchの活性化変異による白血病発症機構の解析
- 2004 - 2005 造毛器腫瘍における抗アポトーシス分子アナモルシンの役割
- 2004 - 2005 Mechanism of leukemogenesis by constitutive active receptor tyrosine kinase
- 2004 - 2005 Analysis on the mechanisms of NF-κB/Reactive Oxigen Species-mediated survival of hematopoietic cells and its clinical application
- 2004 - 2005 Analysis on the mechanisms of growth, differentiation, and survival of megakaryocytic cells
- 2004 - 2004 細胞周期制御分子による造血幹細胞の未分化能の維持及び増幅の試み
- 2003 - 2004 Anamorsin, anti-apoptotic molecule, and hematopoiesis
- 2003 - 2003 活性化変異c-Kit,Flt3の異常シグナル伝達を標的とした治療法の開発
- 2003 - 2003 E2F1による細胞内ROSの蓄積及び癌抑制機構の解析
- 2002 - 2003 造血幹細胞におけるテロメラーゼ活性の制御機構の解析と制御分子の単離の試み
- 2002 - 2003 Analysis on the effects of GATA transcription factors on cell cycle regulatoy molecules in hematopoietic cells
- 2002 - 2003 Analysis of oncogenic signal transduction and target genes by constitutive active mutations of c-Kit and Flt3
- 2002 - 2003 Analysis on the mechanism of survival, growth and differentiation of hematopoietic cells
- 2002 - 2002 活性化変異c-Kit、Flt3の異常シグナル伝達を標的とした治療法の開発
- 2002 - 2002 E2F-1のアポトーシス誘導分子、癌抑制遺伝子としての機能の解析
- 2001 - 2002 Mechanisms of growth, survival and transformation mediated by KIT and FLT3
- 2000 - 2001 Establishment of a sensitive method for detection of PIG-A mutations, and some applications for molecular studies of paroxysual necturnal hemoglobinuric
- 1997 - 1998 Investigation into the molecular mechanism of fatigue sensation
- 1998 - 造血器腫瘍における変異型レセプターチロシンキナーゼの研究
- 1998 - Study on oncogenic receptor tyrosine kinase in hematological neoplasm
- 1997 - 1997 フィブロネクチン/インテグリンVLA5を介する血球のアポトーシス誘導機構
- 1996 - 1997 A Study on development and clonality of PIG-A mutant clones in paroxysmal nocternal hemoglobinuria
- 1995 - 1996 A pathogenetic link between aplastic anemia and paroxysmal nocturnal hemoglobinuria
- 1993 - 1994 The association between acylcarnitine metabolism and general fatigue in the patients with chronic fatigue syndrome
- 1991 - 1991 自己抗原と認識して増殖するLGL白血病の研究
- 腫瘍原性レセプター型チロシンキナーゼに対する新規阻害剤の開発
- T/NK細胞性腫瘍の研究
- Development of novel inhibiotrs against oncogenic receptor tyrosine kinase such as Flt3 or c-Kit
- Study on T/NK lymphoid neoplasms
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- 2003 - 2006 Osaka University Graduate School of Medicine
- 2006 - - 大阪大学医学部附属病院 化学療法部准教授(病院教授)
- 2001 - 2003 Research Assistant, Departemnt of Hematology and Oncology, Osaka University Graduate School of Medicine
- 2003 - - Lecturer, Departemnt of Hematology and Oncology, Osaka University Graduate School of Medicine
- 1998 - 2001 Postdoctoral fellow, Hematolgy/Oncology, Departemnt of Internal Medicine, Muenster University
- 2001 - -2002 大阪大学大学院医学系研究科 血液・腫瘍内科 助手
- 1998 - -2001 ドイツ ミュンスター大学 内科
- 1996 - -1998 大阪大学医学部血液・腫瘍内科 助手
- 1996 - -98 Research Assistant, Department of Hematology and Oncology, Osaka University School of Medicine
- 1993 - -1996 大阪大学医学部血液・腫瘍内科 医員
- 1993 - -96 Senior resident, Department of Hematology and Oncology, Osaka University School of Medicine
- 1988 - -1993 大阪大学微生物病研究所附属病院内科 医員
- 1988 - -93 Senior resisdent, Department of Internal Medicine, Research Institute for Microbial Diseases, Osaka Unversity
- 1986 - -88 大阪大学微生物病研究所附属病院内科 研修医
- 1986 - -88 Junior resisdent, Department of Internal Medicine, Research Institute for Microbial Diseases, Osaka Unversity
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日本臨床腫瘍学会
, 日本癌学会
, 臨床血液学会
, 日本血液学会
, 日本内科学会
, Japanese Cancer Association
, Japanese Society of Clinical Hematology
, Japanese Society of Hematology
, Japanese Society of Internal Medicine
