Tatsuo Fukagawa

フカガワタツオ | Tatsuo Fukagawa

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.fbs.osaka-u.ac.jp/labs/fukagawa/index_j.html

Research field (3)： Cell biology , Molecular biology , Genetics

Research keywords (29)：セントロメア , Kinetochore , DT40細胞 , 染色体分配 , 染色体不安定性 , CENP-A , CENP-H , Nuf2 , RNAiマシーナリー , がん化 , 紡錘体チェックポイント , 染色体工学 , ZW10 , プロテオミクス , 細胞分裂 , Hec1 , ゲノム工学 , CENP-I , CENP-C , CENPs , チェックポイント , Mad , Dicer , ZW250 , SUMO-1 , Mis6 , FRAP , 条件的ノックアウト , Bub

Research theme for competitive and other funds (45)：

2024 - 2029 Biological Cluster: dynamic assembly and functional properties of supramolecular complexes in cells
2021 - 2026 動原体超分子複合体の構造ダイナミクス
2022 - 2025 Comprehensive understanding for centromeres and kinetochores
2022 - 2024 セントロメアの維持・形成に関与する非ゲノム情報
2021 - 2023 セントロメアモダリティの理解

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Papers (168)：

Weixia Kong, Masatoshi Hara, Yurika Tokunaga, Kazuhiro Okumura, Yasuhiro Hirano, Jiahang Miao, Yusuke Takenoshita, Masakazu Hashimoto, Hiroshi Sasaki, Toshihiko Fujimori, et al. CENP-C-Mis12 complex establishes a regulatory loop through Aurora B for chromosome segregation. Life Science Alliance. 2024. 8. 1. e202402927-e202402927
Carlos Sacristan, Kumiko Samejima, Lorena Andrade Ruiz, Moonmoon Deb, Maaike L A Lambers, Adam Buckle, Chris A Brackley, Daniel Robertson, Tetsuya Hori, Shaun Webb, et al. Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin. Cell. 2024. 187. 12. 3006-3023
Yasuhiro Hirano, Tsukino Sato, Ayane Miura, Yoshino Kubota, Tomoko Shindo, Koichi Fukase, Tatsuo Fukagawa, Kazuya Kabayama, Tokuko Haraguchi, Yasushi Hiraoka. Disordered region of nuclear membrane protein Bqt4 recruits phosphatidic acid to the nuclear envelope to maintain its structural integrity. The Journal of biological chemistry. 2024. 300. 7. 107430-107430
Jing Hui Cao, Tetsuya Hori, Mariko Ariyoshi, Tatsuo Fukagawa. Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells. Journal of Cell Science. 2024. 137. 3
Harsh Nagpal, Ahmad Ali-Ahmad, Yasuhiro Hirano, Wei Cai, Mario Halic, Tatsuo Fukagawa, Nikolina Sekulić, Beat Fierz. CENP-A and CENP-B collaborate to create an open centromeric chromatin state. Nature communications. 2023. 14. 1. 8227-8227

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MISC (76)：

平野泰弘, 佐藤つきの, 三浦彩音, 深瀬浩一, 深川竜郎, 樺山一哉, 原口徳子, 平岡泰. 核膜タンパク質Bqt4はホスファチジン酸との結合を介して核膜の恒常性維持を担う. 日本生化学会大会(Web). 2023. 96th
CAO Jinghui, HORI Tetsuya, FUKAGAWA Tatsuo. Analysis for the CENP-I dependent CENP-A incorporation into centromeres. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
堀哲也, 曹静暉, 深川竜郎. 動原体タンパク質に依存したセントロメアの位置情報の書き込みメカニズム. 日本遺伝学会大会プログラム・予稿集. 2022. 94th (CD-ROM)
平野泰弘, 佐藤つきの, 三浦彩音, 樺山一哉, 樺山一哉, 深瀬浩一, 深瀬浩一, 深川竜郎, 原口徳子, 平岡泰. Roles of the lipid-binding region of an inner nuclear membrane protein Bqt4 in fission yeast. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
西村浩平, 深川竜郎, 嘉村巧. Centromere structure analysis by AID system and 4C method. 月刊細胞. 2022. 54. 11

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Education (1)：

- 1995 The Graduate University for Advanced Studies School of Life Science Department of Genetics

Work history (7)：

2015 - 現在 Osaka University Garduate School of Frontier Biosceinces Professor
2008 - 2015 National Institute of Genetics Department of Genetics
2003 - 2008 National Institute of Genetics National Institute of Genetics
2002 - 2003 National Institute of Genetics National Institute of Genetics
2002 - 2003 The Graduate University for Advanced Studies School of Advanced Sciences

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Awards (3)：

2020/09 - 日本遺伝学会日本遺伝学会木原賞セントロメアおよび動原体の分子基盤の解明
2005 - 文部科学省文部科学大臣表彰若手科学者賞
2002 - 日本遺伝学会日本遺伝学会奨励賞

Association Membership(s) (5)：

THE JAPANESE CANCER ASSOCIATION , JAPAN SOCIETY FOR CELL BIOLOGY , THE JAPANESE BIOCHEMICAL SOCIETY , THE GENETICS SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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