Rchr
J-GLOBAL ID:200901061673841764   Update date: Sep. 24, 2024

IKEMOTO Mitsushi J

イケモト ミツシ | IKEMOTO Mitsushi J
Affiliation and department:
Job title: Researcher
Research field  (3): Neuroscience - general ,  Medical biochemistry ,  Molecular biochemistry
Research keywords  (21): 神経可塑性 ,  神経変性疾患 ,  Low-intensity exercises ,  Addicsin (Arl6ip5, GTRAP3-18, JWA) ,  SPARC (Osteonectin) ,  Brain Leptin ,  Astaxisantin ,  Polyphenol ,  Exosome ,  細胞外膜小胞精製法 ,  DNA Aptamer ,  GPCRs ,  Morphine Tolerance & Dependence ,  遺伝子発現 ,  Morphine ,  Neural plascity ,  Reverse Torelance ,  Dependence ,  Torelance ,  Gene expression ,  Drug addiction
Research theme for competitive and other funds  (13):
  • 2024 - 2026 Hippocampal mechanism of astaxanthin mimicking exercise effects: focus on leptin signaling
  • 2024 - 2026 認知症を予防する新たな運動栄養戦略:経鼻投与法の活用
  • 2022 - 2023 認知症を予防する経鼻サプリメントの開発 -天然抗酸化物質アスタキサンチン搭載エキソソームを用いた検証-
  • 2021 - 2023 エクソソーム品質基準規格の策定に向けたシステム開発
  • 2019 - 2021 快適生活をマネジメントする脳フィットネス戦略
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Papers (28):
  • Saho Furukawa, Kyoka Kawaguchi, Kotomi Chikama, Ryohei Yamada, Yuji O. Kamatari, Lee Wah Lim, Hiroko Koyama, Yasuo Inoshima, Mitsushi J. Ikemoto, Saishi Yoshida, et al. Simple methods for measuring milk exosomes using fluorescent compound GIF-2250/2276. Biochemical and Biophysical Research Communications. 2024. 149505-149505
  • Noriyuki Ishii, Keiichi Noguchi, Mitsushi J Ikemoto, Masafumi Yohda, Takayuki Odahara. Optimizing Exosome Preparation Based on Size and Morphology: Insights From Electron Microscopy. Microscopy and Microanalysis. 2023. 29. 2068-2079
  • Kyoka Kawaguchi, Miyu Watanabe, Saho Furukawa, Kenichi Koga, Hiromitsu Kanamori, Mitsushi J. Ikemoto, Shigeo Takashima, Miwa Maeda, Kentaro Oh-Hashi, Yoko Hirata, et al. Intermittent inhibition of FYVE finger-containing phosphoinositide kinase induces melanosome degradation in B16F10 melanoma cells. Molecular Biology Reports. 2023. 50. 7. 5917-5930
  • Mitsushi J. Ikemoto, Yukine Aihara, Noriyuki Ishii, Hideyuki Shigemori. 3,4-Dihydroxybenzalacetone Inhibits the Propagation of Hydrogen Peroxide-Induced Oxidative Effect via Secretory Components from SH-SY5Y Cells. Biological and Pharmaceutical Bulletin. 2023. 46. 4. 599-607
  • Hiroe Toba, Mitsushi J. Ikemoto, Miyuki Kobara, Tetsuo Nakata. Secreted protein acidic and rich in cysteine (SPARC) and a disintegrin and metalloproteinase with thrombospondin type 1 motif (ADAMTS1) increments by the renin-angiotensin system induce renal fibrosis in deoxycorticosterone acetate-salt hypertensive rats. European Journal of Pharmacology. 2022. 914. 174681-174681
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MISC (45):
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Patents (7):
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Lectures and oral presentations  (123):
  • Low-intensity exercise may reduce cognitive decline and hippocampal amyloidosis in APP NL-G-F Alzheimer's disease model mice
    (2024)
  • Exploring intra-hippocampal glycogen as a mediator of hippocampal adaptation through low-intensity exercise: insights from a brain glycogen-deficient mouse model
    (2024)
  • A DNA aptamer generated by the newly developed extracellular vesicle-SELEX method acts on a GPCR super-complex
    (2023)
  • Clovamide関連化合物のアミロイドポリペプチド凝集ならびに神経細胞に対する効果
    (日本ポリフェノール学会第15回学術集会 2022)
  • 未知の神経可塑性制御因子を追い求めて
    (筑波大学 体育系 運動生化学研究室セミナー 2021)
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Professional career (1):
  • Ph. D (Medical) (University of Osaka)
Work history (16):
  • 2023/04 - 現在 University of Tsukuba Faculty of Health and Sport Sciences
  • 2023/04 - 現在 Iwate Medical University
  • 2023/04 - 現在 University of Toyama Faculty of Engineering
  • 2012/04 - 現在 Meisei University School of Science and Engineering
  • 2020/04 - 2023/03 University of Tsukuba Advanced Research Instutute for Human High Performance (ARIHHP) Visiting Researcher
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Association Membership(s) (5):
米国科学研究名誉協会(Sigma Xi)正会員 ,  北米神経科学会(Society For Neurscience) ,  日本神経科学会 ,  日本薬理学会 ,  日本生化学会
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