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J-GLOBAL ID：200901061936826390   Update date: Apr. 12, 2024

Ishii Yuji

イシイ ユウジ | Ishii Yuji
Affiliation and department：
Kyushu University

About Kyushu University


Job title： Associate Professor
Homepage URL  (1)： http://www.phar.kyushu-u.ac.jp
Research field  (6)： Hygiene and public health (non-laboratory) ,  Hygiene and public health (laboratory) ,  Healthcare management, medical sociology ,  Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Molecular biology
Research keywords  (4)： 基磯生物化学 ,  生物系薬学 ,  Basic biological Chemistry ,  Biopharmaceutics
Research theme for competitive and other funds  (21)：
  • 2021 - 2026 内外環境の破綻による次世代影響評価:発達障害と性未成熟の機構の検証と予防
  • 2017 - 2022 Assessment of the impact of the disturbance in endo-and-xeno environment on the next-generation: study on the mechanism for sexual immaturity and developmental disorders and the preventive method
  • 2016 - 2019 Novel hypothesis for phenobarbital induction of drug metabolizing enzyme: Investigation of a model and a mechanism
  • 2013 - 2016 Basic study for appropriate use of clinical medicine: functional interaction of drug metabolizing enzymes and its significance in vivo
  • 2009 - 2011 Bas i s stud i es on the appropr i ate usage of c l i n i ca I med i c i ne : i so form specificity of the functional interaction between drug metabolizing enzymes and the individual differences
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Papers (120)：
  • Jorge Carlos Pineda Garcia, Ren-Shi Li, Ruri Kikura-Hanajiri, Yoshitaka Tanaka, Yuji Ishii. Timeframe Analysis of Novel Synthetic Cannabinoids Effects: A Study on Behavioral Response and Endogenous Cannabinoids Disruption. International journal of molecular sciences. 2024. 25. 6
  • Takayuki Koga, Kie Inoue, Fuka Hirayama, Makoto Hiromura, Kiyonaga Fujii, Yuji Ishii, Masayo Hirao-Suzuki, Shuso Takeda, Akihisa Toda, Fumio Soeda. Dimethylglycine, a methionine metabolite, participates in the suppressive effect of methionine on 1-fluoro-2,4-dinitrobenzene-induced dermatitis. Biological & pharmaceutical bulletin. 2023. 46. 7. 946-954
  • Ming Yuan, Hiroe Sano, Takaaki Nishino, Hongbin Chen, Ren-Shi Li, Yuki Matsuo, Kyoko Nishida, Takayuki Koga, Tomoki Takeda, Yoshitaka Tanaka, et al. α-Lipoic acid eliminates dioxin-induced offspring sexual immaturity by improving abnormalities in folic acid metabolism. Biochemical pharmacology. 2023. 210. 115490-115490
  • Hiroyuki Mohri, Kazuko Mohri, Akinaga Gohda, Yuji Ishii. Rapid derivatization of phosphorus-containing amino acid herbicides in plasma and urine using microwave heating. The Journal of toxicological sciences. 2023. 48. 1. 15-24
  • Yuu Miyauchi, Akane Kimura, Madoka Sawai, Keiko Fujimoto, Yuko Hirota, Yoshitaka Tanaka, Shinji Takechi, Peter I Mackenzie, Yuji Ishii. Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4. Frontiers in pharmacology. 2022. 13. 832931-832931
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MISC (20)：
  • 藤本茉奈, 佐野宏江, LI Ren-Shi, LI Ren-Shi, CHEN Hong-Bin, 古賀貴之, 武田知起, 武田知起, 田中嘉孝, 石井祐次. Epigenetic effects of maternal exposure to TCDD. 衛生薬学・環境トキシコロジー講演要旨集. 2022. 2022
  • 藤本茉奈, 佐野宏江, LI Ren-Shi, LI Ren-Shi, CHEN Hong-Bin, 古賀貴之, 武田知起, 武田知起, 田中嘉孝, 石井祐次. Maternal exposure to TCDD elicits disruption of fatty acid metabolism in fetal hypothalamus: possible mechanism involved in the reduced steroidogenesis. 衛生薬学・環境トキシコロジー講演要旨集. 2021. 2021
  • MING Yuan, 佐野宏江, 西田恭子, 西野隆晃, 古賀貴之, 武田知起, 武田知起, 田中嘉孝, 石井祐次. α-Lipoic acid ameliorates maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin-produced toxicity in the next generation: recovery effect of α-lipoic acid on sexual immaturity in both male and female offsprings. 衛生薬学・環境トキシコロジー講演要旨集. 2021. 2021
  • 宮尾宏哉, 塩路優子, 宮内優, 武田知起, 武田知起, 田中嘉孝, 石井祐次. Aryl hydrocarbon receptor(AHR)欠損ラットにおける低尿酸血症の詳細機構の解明:核酸代謝に着目した検討. 日本薬学会九州支部大会講演要旨集. 2021. 38th (CD-ROM)
  • YUANG Ming, 佐野宏江, 西田恭子, 古賀貴之, 武田知起, 武田知起, 田中嘉孝, 石井祐次. Prevention of toxicity in the next generation caused by maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: recovery effect of α-lipoic acid on sexual immaturity. Journal of Toxicological Sciences. 2021. 46. Supplement
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Books (5)：
  • Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function
    Frontiers Research Topic Ebook, Frontiers Media SA 2018
  • Fifty Years of Cytochrome P450 Research
    Springer Japan 2014
  • 油症研究II 治療と研究の最前線
    九州大学出版会 2010 ISBN:9784798500072
  • 油症発症機構に関する生化学的研究 (共著)
    油症研究-30年の歩み-,九州大学出版 2000
  • Biochemical Studies on cause of YUSHO
    YUSHO A Human Disaster Caused by PCBs and Related Compounds -Progress in YUSHO Study for thirty years- 2000
Education (4)：
  • - 1993 Kyushu University
  • - 1993 Kyushu University Graduate School, Division of Pharmaceutical Sciences
  • - 1988 Fukuoka University Faculty of Pharmaceutical Sciences
  • - 1988 Fukuoka University Faculty of Pharmaceutical Science
Professional career (2)：
  • Master of Pharmaceutical Sciences (Kyushu University)
  • Ph.D.(Doctor of Pharmaceutical Sciences) (Kyushu University)
Work history (6)：
  • 2007 - 現在 Kyushu University Faculty of Pharmaceutical Sciences
  • 2003 - 2006 Kyushu University Faculty of Pharmaceutical Sciences
  • 2001 - 2003 University of Tsukuba Institute of Community Medicine
  • 2000 - 2001 Kyushu University Faculty of Pharmaceutical Sciences
  • 1999 - 2000 九州大学大学院薬学研究科 助手
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Committee career (5)：
  • 2024/01 - 現在 The International Society for the Study of Xenobiotics (ISSX) Council
  • 2017/07 - 現在 日本法中毒学会 理事
  • 2015/06 - 現在 日本法中毒学会 評議員
  • 2015/06 - 現在 日本毒性学会 評議員
  • 2008 - 現在 日本薬物動態学会 評議員
Awards (5)：
  • 2018/09 - 日本薬学会環境・衛生部会 学術賞
  • 2017 - 日本毒性学会 田邊賞
  • 2013/11 - 臨床薬理研究振興財団 第6回臨床薬理研究振興財団研究大賞
  • 2011 - 日本トキシシコロジー学会 田邊賞
  • 2008 - 平成20年度日本薬物動態学会奨励賞
Association Membership(s) (7)：
American Society for Pharmacology and Experimental Therapeutics (ASPET) ,  International Society for the Study of Xenobiotics ,  日本法中毒学会 ,  日本毒性学会 ,  日本生化学会 ,  日本薬物動態学会 ,  日本薬学会
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