Rchr
J-GLOBAL ID:200901062188383614   Update date: Sep. 11, 2024

Minamoto Toshinari

ミナモト トシナリ | Minamoto Toshinari
Affiliation and department:
Job title: 教授
Research field  (2): Digestive surgery ,  Pathobiochemistry
Research keywords  (5): 腫瘍外科学 ,  分子腫瘍学 ,  消化器がん ,  Surgical and molecular oncology ,  Gastrointestinal oncology
Research theme for competitive and other funds  (70):
  • 2022 - 2025 Exploration of the molecular pathways interconnecting malignant phenotypes in therapy-resistant pancreatic cancer toward development of new strategy against therapy resistance
  • 2020 - 2023 GSK3βを基軸とした食道発癌機構の解明と新規治療戦略の開発
  • 2019 - 2022 Assessment of molecular mechanisms of cancer development in colorectal serrated lesions
  • 2019 - 2022 大腸がんの糖代謝改変と細胞核分裂機構を繋ぐ分子経路の解明とがん制御法開発への応用
  • 2017 - 2020 核膜孔タンパク質とクロマチン相互作用による大腸がんの病態解明
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Papers (156):
  • Masahiro Uehara, Takahiro Domoto, Satoshi Takenaka, Osamu Takeuchi, Takeo Shimasaki, Tomoharu Miyashita, Toshinari Minamoto. Glycogen synthase kinase 3β: the nexus of chemoresistance, invasive capacity, and cancer stemness in pancreatic cancer. Cancer Drug Resistance. 2024
  • Kouichi Kitamura, Tyuji Hoshino, Atsushi Okabe, Masaki Fukuyo, Bahityar Rahmutulla, Nobuko Tanaka, Sohei Kobayashi, Tomoaki Tanaka, Takashi Shida, Mashiro Ueda, et al. The Link of mRNA and rRNA Transcription by PUF60/FIR through TFIIH/P62 as a Novel Therapeutic Target for Cancer. International journal of molecular sciences. 2023. 24. 24
  • Masaharu Hazawa, Dini Kurnia Ikliptikawati, Yuki Iwashima, De-Chen Lin, Yuan Jiang, Yujia Qiu, Kei Makiyama, Koki Matsumoto, Akiko Kobayashi, Goro Nishide, et al. Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells. Cell Chemical Biology. 2023
  • Keita Koizumi, Takahiro Domoto, Toshinari Minamoto, Kazuhito Kazuhito, Hideo Nakajima. Deactivation of glycogen synthase kinase-3β by heat shock-inducible tumor small protein attenuates hyperthermia-induced pro-migratory activity in colorectal cancer cells. International Journal of Oncology. 2023. 63. 2
  • Hiroko Ideo, Akiko Tsuchida, Yoshio Takada, Jun Kinoshita, Noriyuki Inaki, Toshinari Minamoto. Suppression of galectin-4 attenuates peritoneal metastasis of poorly differentiated gastric cancer cells. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2023. 26. 3. 352-363
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MISC (70):
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Patents (17):
Lectures and oral presentations  (91):
  • Potential therapeutic effect of targeting glycogen synthase kinase 3b in esophageal squamous cell carcinoma.
    (2020)
  • Glycogen synthase kinase-3b participates in acquired resistance to gemcitabine in pancreatic cancer.
    (2020)
  • 大腸癌の組織学的特徴は病期と関連する.
    (第79回日本癌学会学術総会 2020)
  • 非乳頭十二指腸腺腫、粘膜内癌におけるゲノム・エピゲノムの統合解析
    (第79回日本癌学会学術総会 2020)
  • Glycogen synthase kinase (GSK)-3bを標的とする膵がんのゲムシタビン獲得耐性の克服
    (第79回日本癌学会学術総会 2020)
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Professional career (1):
  • M.D., Ph.D. (Kanazawa University)
Work history (2):
  • 2001 - -: 金沢大学 教授
  • 2001 - -: Kanazawa University
Committee career (15):
  • 2008 - -: 日本癌学会 評議員
  • 2008 - -: Japanese Cancer Association
  • 2008 - 日本癌学会 評議員
  • 2007 - -: 日本消化器がん検診学会 評議員,東海北陸支部評議員
  • 2007 - -: The Japanese Society of Gastroenterological Cancer Screening
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Awards (10):
  • 2003 - 日本学術振興会2003年度日米がん研究協力事業派遣研究員
  • 2003 - 第34回(2002年度)内藤記念科学奨励金
  • 2003 - Alterations in transcription factors in human cancers
  • 2003 - Award from the Naito Foundation
  • 2002 - 2002年度財団法人澁谷学術文化スポーツ振興財団:大学の新技術研究に対する奨金
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Association Membership(s) (34):
日本人類遺伝学会 ,  日本病理学会 ,  World Society of Gastroenterology ,  International Society of Preventive Oncology ,  American Association for Cancer Research ,  日本大腸肛門病学会 ,  日本膵臓学会 ,  日本がん転移学会 ,  日本消化器癌発生学会 ,  日本胃癌学会 ,  日本消化器がん検診学会 ,  日本消化器内視鏡学会 ,  日本消化器病学会 ,  日本癌治療学会 ,  日本癌学会 ,  日本消化器外科学会 ,  日本外科学会 ,  The Japan Society of Human Genetics ,  The Japanese Society of Pathology ,  World Society of Gastroenterology ,  International Society of Preventive Oncology ,  American Association for Cancer Research ,  Japan Society of Coloproctology ,  The Japan Pancreas Society ,  The Japanese Association for Metastasis Research ,  The Japanese Society for gastroenterological Carcinogenesis ,  The Japanese Gastric Cancer Association ,  The Japanese Society of Gastroenterological Cancer Screening ,  Japan Gastroenterological Endoscopy Society ,  Japanese Society of Gastroenterology ,  Japan Society of Clinical Oncology ,  Japanese Cancer Association ,  The Japanese Society of Gastroenterological Surgery ,  Japan Surgical Society
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