Ueno Masaya

ウエノマサヤ | Ueno Masaya

Affiliation and department：
Job title：助教
Homepage URL (1)： http://www.kanazawa-u.ac.jp/~gankenhomejp.html

Research field (3)： Tumor biology , Cell biology , Developmental biology

Research keywords (4)： leukemia , 分子細胞生物学 , nano-life science , biosensor

Research theme for competitive and other funds (12)：

2020 - 2023 がん特異的な栄養代謝経路におけるニコチンアミド代謝の機能解析
2017 - 2020 Understanding of the regulation mechanisms of therapy resistance by mTOR complex 2
2015 - 2019 A study of microenvironment for maintenance or acquisition of malignant property
2014 - 2017 Understanding of the molecular mechanisms of hematopoietic stem cell heterogeneity by quiescence regulatory factors
2008 - 2011 Molecular analysis of hematopoietic stem cell division in the niche

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Papers (60)：

Satoshi Kaito, Kazumasa Aoyama, Motohiko Oshima, Akiho Tsuchiya, Makiko Miyota, Masayuki Yamashita, Shuhei Koide, Yaeko Nakajima-Takagi, Hiroko Kozuka-Hata, Masaaki Oyama, et al. Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization. Nature Communications. 2024. 15. 1
Masaya Ueno, Hiroki Sugiyama, Feng Li, Tatsuya Nishimura, Hiroshi Arakawa, Xi Chen, Xiaoxiao Cheng, Shinji Takeuchi, Yumie Takeshita, Toshinari Takamura, et al. A Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite. Analytical chemistry. 2024
Ryo Yanagiya, Yuji Miyatake, Natsumi Watanabe, Takanobu Shimizu, Akane Kanamori, Masaya Ueno, Sachiko Okabe, Joaquim Carreras, Shunya Nakayama, Ami Hasegawa, et al. Amino acid influx via LAT1 regulates iron demand and sensitivity to PPMX-T003 of aggressive natural killer cell leukemia. Leukemia. 2024
海渡智史, 青山和正, 大島基彦, 中島やえ子, 小出周平, 山下真幸, 上野将也, 平尾敦, 通山薫, 岩間厚志. TOPORSの機能抑制はDNMT1の安定化を介してDNAメチル化阻害剤の効果を増強する. 日本血液学会学術集会. 2023. 85回. 286-286
海渡智史, 青山和正, 大島基彦, 中島やえ子, 小出周平, 山下真幸, 上野将也, 平尾敦, 通山薫, 岩間厚志. TOPORSの機能抑制はDNMT1の安定化を介してDNAメチル化阻害剤の効果を増強する. 日本血液学会学術集会. 2023. 85回. 530-530

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MISC (17)：

倉吉健太, 上野将也, 高瀬雄介, 布施香子, 太田久美子, 田所優子, 平尾敦. FOXOs下流因子を対象とした白血病幹細胞の分化誘導法の開発. 日本血液学会学術集会抄録(Web). 2020. 82nd
Akanksha Chhabra, Andrew J. Lechner, Asha Acharya, Masaya Ueno, Ben Van Handel, Michelle Tallquist, Hanna Mikkola. Essential Function of PDGF-B Signaling In the Placental Microenvironment In Protecting Hematopoietic Progenitors From Erythroid Differentiation. BLOOD. 2010. 116. 21. 661-661
M. Ueno, L. Kong, N. Takakura. PSF1 is essential for bone marrow regeneration. EXPERIMENTAL HEMATOLOGY. 2007. 35. 9. 44-44
L. Kong, M. Ueno, N. Takakura. Quiescence with survival of hematopoietic stem cells in the niche induced by galectin-3. EXPERIMENTAL HEMATOLOGY. 2007. 35. 9. 47-47
Hiroyasu Kidoya, Yoshihiro Yamada, Masaya Ueno, Xiaoyong Huang, Lingyu Kong, Nobuyuki Takakura. Apelin, an induction factor for neovascular maturation. CIRCULATION. 2006. 114. 18. 32-32

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Patents (3)：

1-メチルニコチンアミドの測定方法及びニコチンアミド-N-メチル基転移酵素阻害剤のスクリーニング方法
Psf1遺伝子欠損動物およびその利用方法
SLD5を高発現するがん幹細胞

Lectures and oral presentations (4)：

Identification of FOXOs-mediated differentiation block pathway in LSCs
(第81回日本血液学会学術集会 2019)
Identification of critical downstream molecules of FOXO for targeting leukemic stem cells
(第17回幹細胞シンポジウム 2019)
mTORC2-mediated metabolic processes contributes drug resistance in leukemia
(2018)
mTORC2-mediated metabolic processes contributes drug resistance in leukemia
(2018)

Professional career (1)：

(BLANK) (Kyoritsu University of Pharmacy)

Association Membership(s) (4)：

日本分析化学会 , 日本血液学会 , 日本薬学会 , 日本癌学会

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