Rchr
J-GLOBAL ID：200901062607783407   Update date: Nov. 18, 2024

Yamauchi Junji

ヤマウチ ジュンジ | Yamauchi Junji
Affiliation and department：
Tokyo University of Pharmacy and Life Sciences School of Life Science

About Tokyo University of Pharmacy and Life Sciences School of Life Science


Other affiliations (2)：
  • National Center for Child Health and Development
  • Tokyo Metropolitan Institute of Medical Science
Homepage URL  (1)： http://www.ls.toyaku.ac.jp/~noshinkei/
Research field  (1)： Neuroscience - general
Research keywords  (10)： 疾患モデル ,  創薬標的モデル ,  ミエリン ,  脱ミエリン ,  中枢神経 ,  末梢神経 ,  包括脳ネットワーク ,  脳梁 ,  感覚神経 ,  シグナル伝達
Research theme for competitive and other funds  (9)：
  • 2017 - 2021 Signaling mechanism for myelin maintenance
  • 2013 - 2017 Negative regulation of axonal myelination
  • 2014 - 2016 脱ミエリン病で特異的に活性化される分子経路を抑制することで、病態を改善する試み
  • 2012 - 2014 A search of novel molecular mechanisms regulating neural progenitor cell proliferation in the cerebral cortex
  • 2011 - 2013 Evaluation of a drug-target-molecule for demyelinating disorders using Dock7 knockdown mouse
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Papers (181)：
  • Tomohiro Torii, Yuki Miyamoto, Junji Yamauchi. Myelination by signaling through Arf guanine nucleotide exchange factor. Journal of neurochemistry. 2024
  • Hiroaki Oizumi, Yuki Miyamoto, Chika Seiwa, Masahiro Yamamoto, Nozomu Yoshioka, Seiichi Iizuka, Tomohiro Torii, Katsuya Ohbuchi, Kazushige Mizoguchi, Junji Yamauchi, et al. Lethal adulthood myelin breakdown by oligodendrocyte-specific Ddx54 knockout. iScience. 2023. 26. 10. 107448-107448
  • Tomohiro Torii, Junji Yamauchi. Molecular Pathogenic Mechanisms of Hypomyelinating Leukodystrophies (HLDs). Neurology international. 2023. 15. 3. 1155-1173
  • Remina Shirai, Mizuka Cho, Mikinori Isogai, Shoya Fukatsu, Miyu Okabe, Maho Okawa, Yuki Miyamoto, Tomohiro Torii, Junji Yamauchi. FTD/ALS Type 7-Associated Thr104Asn Mutation of CHMP2B Blunts Neuronal Process Elongation, and Is Recovered by Knockdown of Arf4, the Golgi Stress Regulator. Neurology international. 2023. 15. 3. 980-993
  • Miku Fukawa, Remina Shirai, Tomohiro Torii, Kenta Nakata, Shoya Fukatsu, Takanari Sato, Keiichi Homma, Yuki Miyamoto, Junji Yamauchi. Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation. Biochemical and biophysical research communications. 2023. 664. 50-58
ｍore...
MISC (1)：
  • 多胡 憲治, 多胡 めぐみ, 太田 聡, 河田 浩敏, 堀江 久永, 山内 淳司, 田中 亨, 松儀 実広, 柳澤 健. がん化型Ras変異体はNF-κBの転写活性化を促進する. 日本生化学会大会プログラム・講演要旨集. 2016. 89回. [2T10-07(2P
Professional career (1)：
  • 理学博士 (東京工業大学大学院)
Work history (1)：
  • 2023/09 - 現在 Tokyo Metropolitan Institute of Medical Science
Association Membership(s) (10)：
日本DDXs研究会 ,  日本ミエリン研究会 ,  AAAS ,  ASCB ,  Sfn ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  グリア研究会 ,  ヘスペリジン研究会
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