Rchr
J-GLOBAL ID:200901063314564715
Update date: Aug. 19, 2024
Igarashi Yasuhiro
イガラシ ヤスヒロ | Igarashi Yasuhiro
Affiliation and department:
Job title:
Professor
Research field (1):
Bioorganic chemistry
Research keywords (2):
天然物化学
, Natural Product Chemistry
Research theme for competitive and other funds (20):
- 2019 - 2023 超希少放線菌群における二次代謝能の全容解明を通じた新規創薬資源の開拓
- 2019 - 2022 Fermentation of herb and seaweed powders and determination of chemical structure of effective substance by lactic acid bacterium from marine environment
- 2016 - 2019 Exploration of structural divesisty of secondary metabolites in unstudied microbial species
- 2013 - 2017 Study on the mechanism by which yellow substance increases enzymatic cellulose degradation and isolation of novel yellow substance
- 2012 - 2016 Biosynthesis of structurally unique microbial secondary metabolites
- 2012 - 2015 Application of biosynthetic genes for fungal secondary metabolites by using Cre-loxp system
- 2012 - 2015 Development of antipathogenic agents targeting quorum sensing of Gram-positive bacteria
- 2010 - 2012 Total synthesis and structure activity relationship of natural products with potent anticancer activity and unique structures
- 2009 - 2011 The search for a stimulator of adiponectin expression, a key molecule that has the potential to overcome type 2 diabetes
- 2006 - 2007 Development of seeds of agents to treat type 2 diabetes using the system involving differentiation of preadipocytes as an indicator
- 2005 - 2005 血管新生異常を基本病態とする生活習慣病克服の起爆剤となる生体機能分子シーズの探索
- 2004 - 2005 Development of new antifungal and anti-HIV agents based on the mannose binding quinone glycoside
- 2002 - 2003 Screening of inhibitors for anchorage-independent tumor cell growth from microbial metabolites and their application in cancer chemotherapy
- 2000 - 2001 新規チロシンキナーゼ阻害物質ヒバリマイシンの生合成と構造活性相関
- 微生物由来の生理活性物質の探索
- 抗生物質の作用機構に関する研究
- 抗生物質の合成研究
- Screening of bioactive compounds from micrrorganisms
- Study on the mode of action of antibiotics
- Synthetic study of antibiotics
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Papers (117):
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Marwa Elsbaey, Naoya Oku, Mohamed S A Abdel-Mottaleb, Yasuhiro Igarashi. Allostreptopyrroles A-E, β-alkylpyrrole derivatives from an actinomycete Allostreptomyces sp. RD068384. Beilstein Journal of Organic Chemistry. 2024. 20. 1981-1987
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Feffiana M Amin, Enjuro Harunari, Naoya Oku, Yasuhiro Igarashi. Herbidomicins, two pairs of polyketide tautomers produced by an actinomycete of the genus Herbidospora. The Journal of antibiotics. 2024
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Marwa Elsbaey, Yuki Samaru, Engy Elekhnawy, Naoya Oku, Yasuhiro Igarashi. A new polycyclic tetramate macrolactam from Allostreptomyces RD068384: stereochemistry and antifungal potential. The Journal of antibiotics. 2024. 77. 6. 393-396
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Md Julkar Nime, Yuna Oguri, Naoya Oku, Yasuhiro Igarashi. Structure revision of tricholomenyn B, an antimitotic geranylcyclohexenone rediscovered as a bitter and antibacterial substance, from a basidiomycete Tricholoma japonicum (Shiro-shimeji). The Journal of antibiotics. 2024
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Zhiwei Zhang, Yiwei Ge, Yasuko In, Yasuhiro Igarashi. Botryorhodines K and L, two new cytotoxic depsidones from a fungus of the genus Arcopilus. The Journal of Antibiotics. 2023. 76. 11. 673-677
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MISC (67):
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松雪洋恵, 藤原和, 深谷圭介, 深谷圭介, KARIM Md. Pokon Ul, 五十嵐康弘, 五十嵐康弘, 占部大介, 占部大介. Total synthesis and SAR study of akazaoxime. 日本薬学会年会要旨集(Web). 2021. 141st
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齋藤駿, 渥美幸大, 深谷圭介, 占部大介, 小牧久幸, 五十嵐康弘. 未研究希少放線菌Pseudosporangium属が生産する二次代謝物の精密解析. 日本放線菌学会大会講演要旨集. 2019. 34th
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林昌平, 林昌平, 尾崎太郎, 尾崎太郎, 浅水俊平, 尾仲宏康, 大村智, 供田洋, 池田治生, 奥直也, et al. Genome mining reveals a minimum gene set for the biosynthesis of 32-membered macrocyclic thiopeptides lactazoles. Institute for Fermentation, Osaka. Research Communications. 2018. 32
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井本正哉, 間木重行, 竹本靖, 小林大貴, 笠松誠人, 五十嵐康弘, 田代悦. EGFが誘導する細胞運動における5-リポキシゲナーゼとおよびCysLT1シグナルの役割. 日本分子生物学会年会プログラム・要旨集(Web). 2013. 36th. 2P-0363 (WEB ONLY)
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浅水俊平, 五十嵐康弘, 尾仲宏康. ビオラセイン生合成におけるインドール環転位に関与するVioEの機能解析. 日本農芸化学会大会講演要旨集. 2007. 2007
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Education (4):
- - 1992 The University of Tokyo
- - 1992 The University of Tokyo Graduate School, Division of Agricultural Science
- - 1987 The University of Tokyo
- - 1987 The University of Tokyo Faculty of Agriculture
Professional career (1):
Association Membership(s) (2):
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