Rchr
J-GLOBAL ID:200901063466526525
Update date: Aug. 30, 2024
Miyajima Atsushi
ミヤジマ アツシ | Miyajima Atsushi
Affiliation and department:
Job title:
Project Professor
Homepage URL (1):
http://www.iam.u-tokyo.ac.jp/cytokine/
Research field (1):
Cell biology
Research keywords (6):
regeneration
, サイトカイン
, 幹細胞
, Signal transudation
, Cytokine
, Stem cell
Research theme for competitive and other funds (25):
- 2016 - 2020 Universal implantation platform of regenerated endocrine tissues with rapid hormone secretion through blood flow
- 2014 - 2017 Role of exercise-induced oncostatin M in the treatment of NASH
- 2014 - 2017 Cellular interaction in liver inflammation and regeneration
- 2013 - 2016 肝臓の幹/前駆細胞の性状解析と肝再生・病態における役割
- 2011 - 2016 Regulation of polarity signaling during morphogenesis, remodeling, and breakdown of epithelial tubular structure
- 2010 - 2016 Control of cell fate decision in the cells differentiating to multiple pathways in a step-by-step fashion
- 2010 - 2015 Studies on microenvironment that regulates hematopoietic cells
- 2010 - 2012 Cellular interaction in liver development and pathogenesis
- 2005 - 2009 Mechanism of liver development
- 2006 - 2007 Studies on autommune diseases in OSM deficient mice
- 2001 - 2005 Regulation of cell death by cell cycling
- 2003 - 2004 Role of oncostatin M in the nervous systems
- 2003 - 2004 Molecular mechanism of proliferation and differentiation of hepatocyte.
- 2002 - 2003 Functions of Thymic Epithelial Cells
- 2002 - 2003 造血細胞の分化・死の制御とその破綻
- 2001 - 2002 間葉系幹細胞の発生,増殖と分化機構の解析
- 2000 - 2001 Development of frontier life science research for prevention and therapy of endemic diseases in Asia and the Pacific Rim Region
- 1998 - 2001 Self Renew and Cell Differentiation in Hemopoietic System
- 1998 - 2001 造血細胞のシグナル伝達
- 1996 - 1999 情報伝達とリンパ球の機能分化
- 1997 - 1998 サイトカインによる細胞の増殖分化と細胞死のシグナル伝達
- 1995 - 1998 サイトカインによるシグナル伝達機構の解析
- 1994 - 1998 Signal transduction via receptors for hemopoietic rrouwth factors
- 1995 - 1997 Control of cytokine function by modified signaling molecules
- 1995 - 1997 サイトカインによる造血細胞の増殖制御機構
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Papers (259):
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Luyao Wang, Yuta Koui, Kazuko Kanegae, Taketomo Kido, Miwa Tamura-Nakano, Shigeharu Yabe, Kenpei Tai, Yoshiko Nakajima, Hiroyuki Kusuhara, Yasuyuki Sakai, et al. Establishment of human induced pluripotent stem cell-derived hepatobiliary organoid with bile duct for pharmaceutical research use. Biomaterials. 2024. 310. 122621-122621
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Benedikt Scheidecker, Stéphane Poulain, Masahiro Sugimoto, Taketomo Kido, Takumi Kawanishi, Atsushi Miyajima, Soo Hyeon Kim, Hiroshi Arakawa, Yukio Kato, Masaki Nishikawa, et al. Dynamic, IPSC-derived hepatic tissue tri-culture system for the evaluation of liver physiology in vitro. Biofabrication. 2024. 16. 2. 025037-025037
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Tia Utami, Mathieu Danoy, Rubina Rahaman Khadim, Fumiya Tokito, Hiroshi Arakawa, Yukio Kato, Taketomo Kido, Atsushi Miyajima, Masaki Nishikawa, Yasuyuki Sakai. A highly efficient cell culture method using oxygen-permeable PDMS-based honeycomb microwells produces functional liver organoids from human induced pluripotent stem cell-derived carboxypeptidase M liver progenitor cells. Biotechnology and bioengineering. 2024
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Tadasuke Komori, Tomoko Hisaoka, Ayumi Kotaki, Miki Iwamoto, Atsushi Miyajima, Eiji Esashi, Yoshihiro Morikawa. Blockade of OSMRβ signaling ameliorates skin lesions in a mouse model of human atopic dermatitis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2024. 38. 1. e23359
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Yasuhiro Nakano, Tohru Itoh, Minoru Tanaka, Atsushi Miyajima, Taketomo Kido. Development of a high throughput system to screen compounds that revert the activated hepatic stellate cells to a quiescent-like state. 2023
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MISC (161):
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大河内 仁志, 矢部 茂治, 宮島 篤. 【iPS細胞のDDSへの応用】ヒトiPS細胞由来の膵島細胞(spheroid)を用いたインスリン補充療法. Drug Delivery System. 2020. 35. 4. 293-300
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篠原満利恵, YOU Lau Qiao, YOU Lau Qiao, 前田夏希, 前田夏希, BENEDIKT Scheidecker, BENEDIKT Scheidecker, 木村圭一, 木村圭一, ASTIA Safitri Rizki, et al. 酸素透過性培養基板を用いた肝組織形成. 日本再生医療学会総会(Web). 2019. 18th
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伊藤 暢, 宮島 篤. 画像診断と病理 肝細胞癌におけるprogenitor cell marker 肝癌における前駆細胞マーカーの発現. 肝臓クリニカルアップデート. 2017. 3. 1. 65-68
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Michitaka Matsuda, Atsushi Miyajima, Minoru Tanaka. Oncostatin M plays a crucial role in liver fibrogenesis by regulating cooperation between hepatic stellate cells and macrophages. HEPATOLOGY. 2016. 64. 825A-826A
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Mechanism of Liver Regeneration. 2016. 15. 3. 247-258
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Patents (40):
Education (4):
- - 1980 The University of Tokyo
- Shizuoka University
- Shizuoka University
- The University of Tokyo Graduate School of Science Biophysics and Biochemistry
Professional career (1):
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