Ikegaya Yuji

イケガヤユウジ | Ikegaya Yuji

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Japan Science and Technology Agency PRESTO

Homepage URL (1)： http://yakusaku.jp

Research field (3)： Neuroscience - general , Pharmacology , Pharmaceuticals - health and biochemistry

Research keywords (23)：統合脳・神経回路機能 , 統合脳・統合脳 , 包括脳ネットワーク , 神経細胞分化 , 長期増強 , アストロサイト , グルタミン酸 , 脳情報の解読と制御 , グリア , 樹状突起 , 軸索 , 神経活動 , 顆粒細胞 , 歯状回 , シナプス , 神経細胞 , 苔状線維 , カルシウム , イメージング , シナプス可塑性 , カルシウム画像法 , 神経回路 , 海馬

Research theme for competitive and other funds (27)：

2022 - 2029 記憶メカニズムの多次元解析 - nmからメゾスケール/ミリ秒から日スケールまで
2023 - 2026 How to escape from boredom: developmental and neurophysiological mechanisms
2018 - 2023 Generation and Collapse of Time Processing and its Emotional Value
2019 - 2022 Suppression of epileptic seizures by regulating astrocytic cAMP signaling
2018 - 2019 Information correlation and its dynamics in back-propagation from the hippocampus to the dentate gyrus

2017 - 2019 Characteristics of hippocampal CA2 circuits

2014 - 2018 Exploring the brain circuit principles using nerve fiber imaging

2013 - 2018 Search for neural mechanisms by which memories create time

2013 - 2018 The science of mental time--Investigation into the past, present, and future

2014 - 2016 Neural prosthesis with a geomagnetic compass

2010 - 2016 Mesoscopic neurocircuitry: towards understanding of the functional and structual basis of brain information processing

2010 - 2014 メゾ回路のグラフ依存的な演算特性の解析

2010 - 2013 脳回路のセルフリライト性の探求

2011 - 2012 Astrocytes drive respiratory rhythm testing a new paradigm

2011 - 2011 Spatial-temporal structure of synaptic inputs-large-scale spine imaging study-

2010 - 2011 逆問題を解くことでシナプス可塑性に迫る

2008 - 2009 海馬神経回路の活動パターンの形成と維持

2007 - 2008 in vivo脳深部で多ニューロン活動を可視化する-次世代ツールを目指して

2006 - 2007 海馬回路機能の出入力相関とシナプス可塑性の大規模イメージング

2005 - 2007 神経可塑性に伴う回路レベルでの機能変化の解析と薬理学的検討

2005 - 2006 「ニューロン-グリア-血管」-異種細胞ネットワーク機能の大規模なリアルタイム解析

2005 - 2005 海馬ニューロンの自発発火活動の時空構造にみる回路発達とシナプス可塑性

2000 - 2004 生体内物質によるシナプス可塑性および記憶・学習行動の調節機構

2002 - 2003 海馬神経回路の持続的新生のメカニズムと生理機能の解明

2002 - 2002 神経細胞死を伴わない樹状突起の形態変性による神経機能の変容

2001 - 2002 造血幹細胞の神経(幹)細胞への転換

2000 - 2001 軸索を切断された神経細胞のシナプス再生機能の解析

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Papers (126)：

Tetsuhiko Kashima, Takuya Sasaki, Yuji Ikegaya. Optogenetic estimation of synaptic connections in brain slices. Journal of neuroscience methods. 2024. 110298-110298
Airi Yoshimoto, Shota Morikawa, Eriko Kato, Haruki Takeuchi, Yuji Ikegaya. Top-down brain circuits for operant bradycardia. Science. 2024. 384. 6702. 1361-1368
Izumi Uehara, Yuji Ikegaya. The meaning of boredom. EMBO Reports. 2024
Haruya Yagishita, Yasuhiro Go, Kazuki Okamoto, Nariko Arimura, Yuji Ikegaya, Takuya Sasaki. A method to analyze gene expression profiles from hippocampal neurons electrophysiologically recorded in vivo. Frontiers in Neuroscience. 2024. 18
Toya Okonogi, Nahoko Kuga, Musashi Yamakawa, Tasuku Kayama, Yuji Ikegaya, Takuya Sasaki. Stress-induced vagal activity influences anxiety-relevant prefrontal and amygdala neuronal oscillations in male mice. Nature communications. 2024. 15. 1. 183-183

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MISC (91)：

Tasuku Araki, Yuji Ikegaya, Ryuta Koyama. The effects of microglia- and astrocyte-derived factors on neurogenesis in health and disease. European Journal of Neuroscience. 2021. 54. 5. 5880-5901
Megumi Andoh, Yuji Ikegaya, Ryuta Koyama. Microglia modulate the structure and function of the hippocampus after early-life seizures. Journal of Pharmacological Sciences. 2020. 144. 4. 212-217
Ryuta Koyama, Yuji Ikegaya. The molecular and cellular mechanisms of axon guidance in mossy fiber sprouting. Frontiers in Neurology. 2018. 9. MAY
Mengxuan Gao, Motoshige Sato, Yuji Ikegaya. Machine learning-based prediction of seizure-inducing action as an adverse drug effect. Yakugaku Zasshi. 2018. 138. 6. 809-813
Mikami Yoshinori, Kanemaru Kazunori, Okubo Yohei, Nakaune Takuya, Suzuki Junji, Kakizawa Sho, Shibata Kazuki, Koyama Ryuta, Murayama Takashi, Ito Akihiro, et al. てんかんモデルマウスにおける1型リアノジン受容体のS-ニトロシル化を介した神経細胞死(S-nitrosylation of the type 1 ryanodine receptor is critical for epileptic seizure-induced neuronal cell death). The Journal of Physiological Sciences. 2017. 67. Suppl.1. S147-S147

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Professional career (1)：

Work history (4)：

2014/04 - 現在 The University of Tokyo Graduate School of Pharmaceutical Sciences
2007/08 - 2014/03 The University of Tokyo Graduate School of Pharmaceutical Sciences
2006/02 - 2007/07 The University of Tokyo Graduate School of Pharmaceutical Sciences
1998/04 - 2006/01 The University of Tokyo Graduate School of Pharmaceutical Sciences

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