Research keywords (6):
生物化学反応
, 超臨界流体・イオン液体における分子ダイナミクスおよび溶媒効果
, 振動分光
, Photochemistry in Proteins
, Solvation and Molecular Dynamics in Supercritical fluids/Ionic liquids
, Vibrational spectroscopy
Research theme for competitive and other funds (12):
2021 - 2024 Probing conformational changes in protein reaction sites via Raman optical activity
2017 - 2020 ラマン光学活性分光法による光受容タンパク質の反応中間体の計測と応用
2016 - 2019 Molecular Basis of light-dependent signal transduction in cells
2016 - 2018 Raman光学活性に基づく生体内反応の立体構造ダイナミクスの観測
2015 - 2016 ラマン光学活性分光法を用いた基質結合型タンパク質の精密構造決定
2012 - 2015 青色光センサーの超高速反応ダイナミクス
2010 - 2012 非線形ラマン分光法による発光タンパク質の研究
2008 - 2010 イオン液体の分子間振動ダイナミクス
2008 - 2010 Intermolecular Vibrational Dynamics in Ionic Liquids
2010 - Ultrafast structural dynamics in protein
2003 - 2008 超臨界水・アルコール中における溶媒和
2003 - 2008 Solvent Effects in Supercritical Water and Supercritical Alcohols
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Papers (48):
Kana Miyazaki, Takashi Kikukawa, Masashi Unno, Tomotsumi Fujisawa. Chromophore Structural Change during the Photocycle of a Light-Driven Cl- Pump from Mastigocladopsis repens: A Cryogenic Raman Study. The journal of physical chemistry. B. 2024. 128. 40. 9692-9698
Tomotsumi Fujisawa, Nozomi Tanaka, Jun Tamogami, Masashi Unno. Retinal Chromophore Configuration in the O Intermediate of Sensory Rhodopsin II from Natronomonas pharaonis. Biochemistry. 2024
Takanari Kamo, Takaaki Matsushita, Masako Hamada, Tomotsumi Fujisawa, Toshihiko Eki, Masashi Unno, Yuu Hirose. Probing Bilin-Protein Interaction in the Protochromic Photocycle of Cyanobacteriochrome RcaE by Site-Directed Mutagenesis. Plant And Cell Physiology. 2024
Takayuki Nagae, Yuya Fujita, Tatsuya Tsuchida, Takanari Kamo, Ryoka Seto, Masako Hamada, Hiroshi Aoyama, Ayana Sato-Tomita, Tomotsumi Fujisawa, Toshihiko Eki, et al. Green/red light-sensing mechanism in the chromatic acclimation photosensor. Science Advances. 2024. 10. 24
Ewa Machalska, Monika Halat, Takumi Tani, Tomotsumi Fujisawa, Masashi Unno, Andrzej Kudelski, Malgorzata Baranska, Grzegorz Zając. Why Does One Measure Resonance Raman Optical Activity? A Unique Case of Measurements under Strong Resonance versus Far-from-Resonance Conditions. The Journal of Physical Chemistry Letters. 2024. 15. 18. 4913-4919
Tomotsumi Fujisawa, Masashi Unno. Near-Infrared Excited Raman Optical Activity as a Tool to Uncover Active Sites of Photoreceptor Proteins. The Journal of Physical Chemistry B. 2024. 128. 10. 2228-2235
Tomotsumi Fujisawa, Masashi Unno. Advanced spectral analysis of complex molecular system. Molecular and Laser Spectroscopy: Advances and Applications: Volume 3. 2022. 25-54
Masashi Unno, Yuu Hirose, Masaki Mishima, Takashi Kikukawa, Tomotsumi Fujisawa, Tatsuya Iwata, Jun Tamogami. Spectroscopic approach for exploring structure and function of photoreceptor proteins. Biophysics and physicobiology. 2021. 18. 127-130
永江峰幸, 海野雅司, 小泉太貴, 宮ノ入洋平, 藤澤知績, 増井健人, 加茂尊也, 和田啓, 浴俊彦, 伊藤隆, et al. Structural basis of the red-absorbing state of cyanobacteriochrome RcaE that regulates complementary chromatic acclimation in cyanobacteria. 日本植物生理学会年会(Web). 2021. 62nd
Tomotsumi Fujisawa. Raman Optical Activity of Proteins. Encyclopedia of Analytical Chemistry. 2020. 1-19