Research keywords (6):
生物化学反応
, 超臨界流体・イオン液体における分子ダイナミクスおよび溶媒効果
, 振動分光
, Photochemistry in Proteins
, Solvation and Molecular Dynamics in Supercritical fluids/Ionic liquids
, Vibrational spectroscopy
Research theme for competitive and other funds (11):
2021 - 2024 Probing conformational changes in protein reaction sites via Raman optical activity
2017 - 2020 ラマン光学活性分光法による光受容タンパク質の反応中間体の計測と応用
2016 - 2018 Raman光学活性に基づく生体内反応の立体構造ダイナミクスの観測
2015 - 2016 ラマン光学活性分光法を用いた基質結合型タンパク質の精密構造決定
2012 - 2015 青色光センサーの超高速反応ダイナミクス
2010 - 2012 非線形ラマン分光法による発光タンパク質の研究
2008 - 2010 イオン液体の分子間振動ダイナミクス
2008 - 2010 Intermolecular Vibrational Dynamics in Ionic Liquids
2010 - Ultrafast structural dynamics in protein
2003 - 2008 超臨界水・アルコール中における溶媒和
2003 - 2008 Solvent Effects in Supercritical Water and Supercritical Alcohols
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Papers (48):
Tomotsumi Fujisawa, Kouta Kinoue, Ryouhei Seike, Takashi Kikukawa, Masashi Unno. Configurational Changes of Retinal Schiff Base during Membrane Na+ Transport by a Sodium Pumping Rhodopsin. The journal of physical chemistry letters. 2024. 15. 7. 1993-1998
Tomotsumi Fujisawa, Takahito Shingae, Jie Ren, Shojiro Haraguchi, Takeshi Hanamoto, Wouter D. Hoff, Masashi Unno. Spectroscopic Validation of Crystallographic Structures of a Protein Active Site by Chiroptical Spectroscopy. Journal of Physical Chemistry Letters. 2023. 14. 41. 9304-9309
Kouhei Nishikawa, Ryosuke Kuroiwa, Jun Tamogami, Masashi Unno, Tomotsumi Fujisawa. Raman Optical Activity of Retinal Chromophore in Sensory Rhodopsin II. The Journal of Physical Chemistry B. 2023. 127. 33. 7244-7250
Masaiku Ohya, Takashi Kikukawa, Junpei Matsuo, Takashi Tsukamoto, Ryota Nagaura, Tomotsumi Fujisawa, Masashi Unno. Structure and Heterogeneity of Retinal Chromophore in Chloride Pump Rhodopsins Revealed by Raman Optical Activity. The journal of physical chemistry. B. 2023
Tao Wu, Petr Bouř, Tomotsumi Fujisawa, Masashi Unno. Molecular Vibrations in Chiral Europium Complexes Revealed by Near-Infrared Raman Optical Activity. Advanced Science. 2023
永江峰幸, 海野雅司, 小泉太貴, 宮ノ入洋平, 藤澤知績, 増井健人, 加茂尊也, 和田啓, 浴俊彦, 伊藤隆, et al. Structural basis of the red-absorbing state of cyanobacteriochrome RcaE that regulates complementary chromatic acclimation in cyanobacteria. 日本植物生理学会年会(Web). 2021. 62nd
Tomotsumi Fujisawa. Raman Optical Activity of Proteins. Encyclopedia of Analytical Chemistry. 2020. 1-19