Research field (4)：
Environmental effects of chemicals
, Environmental effects of radiation
, Pharmacology
, Pharmaceuticals - health and biochemistry
Research keywords (4)：
遺伝毒性学
, 変異機構学
, Genotoxicology
, Mutagenesis
Research theme for competitive and other funds (6)：
2019 - 2022 Survay on carcinogenic risks by oral bacteria and their measures
2015 - 2019 Analysis of photochemical activation of endogenic and environmental N-nitrosamines and its photogenotoxicity and disturbance on cell functions
2011 - 2013 UVA activated N-nitrosoproline induced damages on DNA, protein and membrane, and disturbance of signal transduction
2008 - 2010 DNA and protein modification and disturbance on cell system with NO produced from photo-reactivation of N-nitrosated amino acids
2003 - 2005 Reaction mechanisms and evaluation of toxicity of the formation of nitric oxide from UVA-irradiated N-nitroso-compound
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Papers (132)：
Sakae Arimoto-Kobayashi, Ryoko Hida, Nana Fujii, Ryosuke Mochioka. Antimutagenic, anti-inflammatory, and antioxidative activities of the juice of Vitis ficifolia var. Ganebu, a woody vine in the grape family, known as Ryukyu-ganebu in Japan. Genes and Environment. 2021. 43. 1
Sakae Arimoto-Kobayashi, Kensuke Sasaki, Ryoko Hida, Naoko Miyake, Nana Fujii, Yusuke Saiki, Kyohei Daimaru, Hirono Nakashima, Toshio Kubo, Katsuyuki Kiura. Chemopreventive effects and anti-tumorigenic mechanisms of 2,6-dimethoxy-1,4-benzoquinone, a constituent of Vitis coignetiae Pulliat (crimson glory vine, known as yamabudo in Japan), toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice. Food and Chemical Toxicology. 2021. 154. 112319-112319
Yuki Kitamura, Mayuko Sakanashi, Azuki Ozawa, Yuri Saeki, Ayano Nakamura, Yuiho Hara, Ken-ichi Saeki, Sakae Arimoto-Kobayashi. Protective effect of Actinidia arguta in MPTP-induced Parkinson’s disease model mice. Biochemical and Biophysical Research Communications. 2021. 555. 154-159
Chiharu Asahi, Shuhei Aoyama, Sachiko Kimura, Toshinori Suzuki, Tsutomu Hatano, Sakae Arimoto-Kobayashi. Isolation of new photoadducts from UVA-irradiated N-nitrosoproline with 2'-deoxyadenosine and characterization of photoadducts from DNA irradiated with N-nitrosoproline. Journal of Photochemistry and Photobiology A: Chemistry. 2020. 400. 112621-112621
Ken-Ichi Yamamoto, Hiroko Kagawa, Sakae Arimoto, Xian Wen Tan, Kento Yasui, Toshiyuki Oshiki, Masakiyo Sakaguchi. Cytotoxic Effects of Alcohol Extracts from a Plastic Wrap (Polyvinylidene Chloride) on Human Cultured Liver Cells and Mouse Primary Cultured Liver Cells. Acta medica Okayama. 2020. 74. 4. 327-334
Ichihara Hidenori, Negishi Tomoe, Arimoto Sakae. P-045 Effects of photo irradiation on the mutagenicity of sidestream smoke of cigarette(Poster Sessions). 2015. 44. 115-115
Arimoto Sakae, Miyake Naoko, Tada Misako, Negishi Tomoe. P-061 Inhibitory effect of vinegar-extract of A. arguta on 1,2-dimethylhydrazine induced colon preneoplastic lesion in male F344 rat(Poster Sessions). 2015. 44. 123-123
Kawata, K, Morishita, K, Yamada, S, Nakayama, M, Kobayashi, T, Furusawa, Y, Arimoto-Kobayashi, S, Oohashi, T, Makishima, M, Naitou, H, et al. RXR partial agonist produced by side-chain repositioning of alkoxy RXR full agonist retains anti-type 2 diabetes activity without the adverse effects. Journal of Medicinal Chemistry. 2015. 58. 2. 912-926
Beer in ‘Chemoprevention of Cancer and DNA Damage by Dietary Factors’
2009 ISBN:9783527320585
Beer in Health and Disease Prevention (共著)
Academic Press 2008
Inhibitory effects of beer and other alcoholic beverages on the mutagenesis and DNA-adduct formations induced by several carcinogens: identification of one of the antimutagenic factors. Dietary Anticarcinogens and Antimutagens, Chemical and Biological Aspects
2000
Inhibitory activity of natural chlorophylls on the mutagenicity of 4-nitroquinoline-1-oxide and 3-amino-1-methyl-5H-pyrido[4,3-b]indole in Drosophila. Food Factors for Cancer Prevention
1997
