SHIDA TOSHIO

シダトシオ | SHIDA TOSHIO

Affiliation and department：
Job title： Professor Emeritus

Research field (2)： Biophysics , Molecular biology

Research keywords (7)： Enzyme engineering , Molecular biology , Bacillus subtilis , cell wall lytic enzyme , cell wall (peptidoglycan) , DNA repair enzyme , nucleic acid

Research theme for competitive and other funds (7)：

新規バイオファイバーマテリアルの微生物生産および微生物酵素を利用した生産に関する研究
微生物の細胞壁(ペプチドグリカン)を溶解する酵素の構造と機能および応用に関する研究
特殊な構造をとる核酸の構造化学的性質に関する研究
DNA損傷によるDNAの構造変化と突然変異および修復に関する蛋白質に関する研究
遺伝子組換えに関与する蛋白質とDNAの相互作用に関する研究

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Papers (6)：

N. Tabata, T. Kodera, R. Arai, T. Shida. Recogunitoin model of uracil residues in DNA by AP endonuclease from Methanothermobacter thermatotrophicus. Photon Factory Activity Report. 2013. 2012. #30 B
Naoko Ohnami, Akihiro Nakamura, Mami Miyado, Masahiro Sato, Natsuko Kawano, Keiichi Yoshida, Yuichirou Harada, Youki Takezawa, Seiya Kanai, Chihiro Ono, et al. CD81 and CD9 work independently as extracellular components upon fusion of sperm and oocyte. BIOLOGY OPEN. 2012. 1. 7. 640-647
Y. Yamada, T. Kodera, K. Ohnishi, K. Kaneda, T. Shida. Incipent Complex Formation between AP Endonuclease and DNA contining AP site: A Vital Role of the Tryptophan Residue. Nucleic Acids Symposium. 2009. 53. 309-310
Tatsuya Fukushima, Toshihiko Kitajima, Hiroyuki Yamaguchi, Qin Ouyang, Kazumi Furuhata, Hiroki Yamamoto, Toshio Shida, Junichi Sekiguchi. Identification and characterization of novel cell wall hydrolase CwIT - A two-domain autolysin exhibiting N-acetylmuramidase and DL-endopeptidase activities. JOURNAL OF BIOLOGICAL CHEMISTRY. 2008. 283. 17. 11117-11125
Kohichi Kaneda, Kaori Ohishi, Junichi Sekiguchi, Toshio Shida. Characterization of the AP endonucleases from Thermoplasma volcanium and Lactobacillus plantarum: Contributions of two important tryptophan residues to AP site recognition. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY. 2006. 70. 9. 2213-2221

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MISC (1)：

志田敏夫. DNA修復酵素APエンドヌクレアーゼ研究から見えてきた基質認識メカニズム. 生化学. 2011. 88. 7. 618-623

Books (2)：

はじめて学ぶ繊維
日刊工業新聞社 2011
はじめて学ぶ繊維
工業調査会 2008

Lectures and oral presentations (2)：

Functional analysis of tetraspanin CD9 in sperm-egg fusion
(6th International Conference on Advanced Fiber/Textile Materials 2011 in Ueda 2011)
Incipient complex formation between AP endonuclease and DNA containing AP site: A vital role of the tryptophan residue
(6th International Symposium on Nucleic Acids Chemistry 2009)

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