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J-GLOBAL ID:200901065169335527   Update date: Sep. 19, 2024

Masutani Chikahide

マスタニ チカヒデ | Masutani Chikahide
Affiliation and department:
Job title: Professor
Research field  (1): Molecular biology
Research theme for competitive and other funds  (43):
  • 2016 - 現在 ヒト細胞のDNA損傷トレランスの連携制御メカニズムの解析
  • 2021 - 2023 DNA損傷によるDNA複製の阻害と転写の阻害を連携制御するメカニズムの解析
  • 2020 - 2023 ヒト細胞のDNA損傷トレランスの分子機構と細胞レベルの機能の解析
  • 2013 - 2016 DNA損傷による複製阻害を回避するメカニズムの包括的理解
  • 2012 - 2015 Biochemical study on the molecular mechanisms of induced mutagenesis and post-replication repair pathways
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Papers (127):
  • Yohei Sugimoto, Yuji Masuda, Shigenori Iwai, Yumi Miyake, Rie Kanao, Chikahide Masutani. Novel mechanisms for the removal of strong replication-blocking HMCES- and thiazolidine-DNA adducts in humans. Nucleic acids research. 2023
  • Rie Kanao, Hidehiko Kawai, Toshiyasu Taniguchi, Minoru Takata, Chikahide Masutani. RFWD3 and translesion DNA polymerases contribute to PCNA modification-dependent DNA damage tolerance. Life science alliance. 2022. 5. 12
  • Yuina Sonohara, Reine Takatsuka, Chikahide Masutani, Shigenori Iwai, Isao Kuraoka. Acetaldehyde induces NER repairable mutagenic DNA lesions. Carcinogenesis. 2021
  • Masuda Y, Saeki Y, Arai N, Kawai H, Kukimoto I, Tanaka K, Masutani C. Stepwise multipolyubiquitination of p53 by the E6AP-E6 ubiquitin ligase complex. The Journal of biological chemistry. 2019. 294. 41. 14860-14875
  • Masuda Yuji, Masutani Chikahide. Spatiotemporal regulation of PCNA ubiquitination in damage tolerance pathways. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2019. 54. 5. 418-442
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MISC (47):
  • Yuji Masuda, Rie Kanao, Chikahide Masutani. Biochemical analysis of HLTF, a human homologue of SWI/SNF-related ubiquitin ligase RAD5. GENES & GENETIC SYSTEMS. 2016. 91. 6. 366-366
  • Yuji Masuda, Rie Kanao, Chikahide Masutani. Stimulation of human DNA polymerase eta by PCNA. GENES & GENETIC SYSTEMS. 2015. 90. 6. 368-368
  • Masuda Yuji, Kanao Rie, Masutani Chikahide. P-002 Interaction between PCNA and human DNA polymerase eta(Poster Sessions). 2015. 44. 93-93
  • Yuji Masuda, Rie Kanao, Haruo Ohmori, Fumio Hanaoka, Chikahide Masutani. Analysis of PCNA interacting motifs of DNA polymerase. GENES & GENETIC SYSTEMS. 2014. 89. 6. 309-309
  • Christian Biertuempfel, Ye Zhao, Yuji Kondo, Santiago Ramon-Maiques, Mark Gregory, Jae Young Lee, Chikahide Masutani, Alan R. Lehmann, Fumio Hanaoka, Wei Yang. Structure and mechanism of human DNA polymerase eta (vol 465, pg 1044, 2010). NATURE. 2011. 476. 7360. 360-360
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Books (23):
  • Translesion DNA synthesis (in "DNA Repair Disorders" edited by Nishigori and Sugasawa)
    Springer 2019
  • Translesion DNA synthesis and damage tolerance pathways (in DNA Replication, Recombination, and Repair - Molecular Mechanisms and Pathology" edited by Hanaoka and Sugasawa)
    Springer 2016
  • DNA polymerase eta (in "Function of Translesion DNA Polymerases in Genome Stability" edited byMariorano and Hoffmann)
    Research Signpost 2015
  • Human DNA polymerase eta and its regulatory mechanisms.
    Genes and Environment 2012
  • 動物細胞の紫外線DNA損傷の修復と複製
    蛋白質核酸酵素2009年3月号増刊「染色体サイクル」 2009
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Professional career (1):
  • Ph.D. (The University of Tokyo)
Work history (9):
  • 2010/09/01 - 現在 Nagoya University Research Institute of Environmental Medicine Division of Stress Adaptation and Protection Professor
  • 2010/09 - Nagoya University Research Institute of Environmental Medicine
  • 2007/04 - 2010/08 Osaka University Graduate School of Frontier Biosciences
  • 2005/07 - 2007/03 Osaka University Graduate School of Frontier Biosciences
  • 2002/04 - 2005/06 Osaka University Graduate School of Frontier Biosciences
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