Rchr
J-GLOBAL ID:200901065378034674   Update date: Apr. 17, 2024

Hiroyuki Shimada

シマダ ヒロユキ | Hiroyuki Shimada
Affiliation and department:
Job title: Assistant Professor/Senior Assistant Professor
Research field  (1): Fetal medicine/Pediatrics
Research theme for competitive and other funds  (5):
  • 2014 - 2018 Flow cytometric analysis to predict prognosis in children with chronic-phase CML treated with imatinib
  • 2013 - 2016 Genome- and gene expression-based drug discovery for pediatric Philadelphia chromosome positive leukemia
  • 2010 - 2012 Proteomic analysis of phosphorylation in leukemic cells
  • 2005 - 2006 Identification of genetic defect coupled with the susceptibility to childhood leukemia
  • 2002 - 2004 ホメオボックス遺伝子による造血制御およびその破綻による白血病発症機構の解析
Papers (57):
  • Haruko Shima, Akiko Kada, Akihiko Tanizawa, Iori Sato, Chikako Tono, Masaki Ito, Yuki Yuza, Akihiro Watanabe, Kiyoko Kamibeppu, Hideko Uryu, et al. Discontinuation of tyrosine kinase inhibitors in pediatric chronic myeloid leukemia. Pediatric blood & cancer. 2022. 69. 8. e29699
  • Yuichi Kodama, Atsushi Sato, Keisuke Kato, Hirotoshi Sakaguchi, Motohiro Kato, Hirohide Kawasaki, Hidefumi Hiramatsu, Itaru Kato, Takashi Taga, Hiroyuki Shimada. Ponatinib in pediatric patients with Philadelphia chromosome-positive leukemia: a retrospective survey of the Japan Children's Cancer Group. International journal of hematology. 2022. 116. 1. 131-138
  • Hiroyuki Shimada, Akihiko Tanizawa, Takeshi Kondo, Tokiko Nagamura-Inoue, Masahiro Yasui, Arinobu Tojo, Hideki Muramatsu, Tetsuya Eto, Noriko Doki, Masatsugu Tanaka, et al. Prognostic Factors for Outcomes of Allogeneic HSCT for Children and Adolescents/Young Adults With CML in the TKI Era. Transplantation and cellular therapy. 2022. 28. 7. 376-389
  • Haruna Yoshikawa, Takeshi Sato, Takahiro Ishikawa, Jumpei Ito, Fumito Yamazaki, Haruko Shima, Misa Honda, Hironori Shibata, Tomohiro Ishii, Hiroshi Asanuma, et al. Potential benefits of rapid genetic testing for germline WT1 in infants with bilateral renal tumors: A case report. Pediatric blood & cancer. 2022. 69. 2. e29368
  • Hiroyuki Shimada. [Treatment strategy for Philadelphia chromosome-positive acute lymphoblastic leukemia in children]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2022. 63. 7. 799-804
more...
MISC (11):
  • Yuichi Kodama, Atsushi Sato, Keisuke Kato, Motohiro Kato, Hirohide Kawasaki, Hirotoshi Sakaguchi, Hidefumi Hiramatsu, Itaru Kato, Takashi Taga, Hiroyuki Shimada. Ponatinib in Pediatric Patients with Philadelphia Chromosome-Positive Leukemia - Japanese Pediatric Leukemia/Lymphoma Study Group. PEDIATRIC BLOOD & CANCER. 2020. 67
  • 嶋 晴子, 谷澤 昭彦, 黒澤 秀光, 渡辺 輝浩, 伊藤 正樹, 遠野 千佳子, 湯坐 有希, 村松 秀城, 浜本 和子, 岡田 雅彦, et al. 小児慢性期CMLにおけるチロシンキナーゼ阻害剤が成人身長に及ぼす影響(JPLSG CML11研究)(Impact of tyrosine kinase inhibitor on adult height in chronic-phase CML children). 臨床血液. 2018. 59. 9. 1561-1561
  • Akihiko Tanizawa, Hidemitsu Kurosawa, Akihiro Watanabe, Masaki Ito, Chikako Tono, Haruko Shima, Yuki Yuza, Kazuko Hamamoto, Noriko Hotta, Hideki Muramatsu, et al. A Multicenter Prospective Observational Study for Chronic-phase Pediatric CML (JPLSG CML-08): Preliminary Analysis of BCL-ABL1 Mutation (2017). PEDIATRIC BLOOD & CANCER. 2017. 64. S26-S26
  • Yuki Yuza, Hiroyuki Shimada, Hidemitsu Kurosawa, Akihiro Watanabe, Masaki Ito, Chikako Tono, Haruko Shima, Kazuko Hamamoto, Hideki Muramatsu, Noriko Hotta, et al. A 2017 Multicenter, Prospective Observational Study for Pediatric CML in CP (JPLSG CML-08): A Preliminary Analysis of Adverse Events. PEDIATRIC BLOOD & CANCER. 2017. 64. S26-S26
  • Haruko Shima, Akihiko Tanizawa, Hidemitsu Kurosawa, Aki-hiro Watanabe, Masaki Ito, Chikako Tono, Yuki Yuza, Kazuko Hamamoto, Hideki Muramatsu, Noriko Hotta, et al. Effect of 2nd Generation TKI on Treatment Response in Imatinib-resistant or Intolerant CP-CML Children; JPLSG CML-08 Study. PEDIATRIC BLOOD & CANCER. 2017. 64. S27-S27
more...
Lectures and oral presentations  (1):
  • Hodgkin lymphomaとの鑑別に苦慮したclusterin陽性anaplastic large cell lymphomaの1例
    (第43回日本小児血液学会 2001)
Education (1):
  • 1992 - 1992 Keio University 医学部
Professional career (1):
  • 医学 (慶應義塾大学)
Work history (6):
  • 2006/11 - 現在 Instructor, Department of Pediatrics, Keio University School of Medicine
  • 2000/07 - 現在 慶應義塾大学医学部助手(小児科)
  • 1999/07 - 現在 国立がんセンター研究所 派遣研究員(放射線研究部)
  • 1996/07 - 現在 国立がんセンター研究所 リサーチ・レジデント(放射線研究部)
  • 1994/05 - 現在 慶應義塾大学医学部専修医(小児科)
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Awards (4):
  • 2005/11/25 - 平成17年度私立大学情報教育協会賞
  • 2005/11/08 - 慶應医学会 三四会奨励賞 Analysis of Genes Under the Downstream Control of the t(8;21) Fusion Protein AML1-MTG8: Overexpression of the TIS11b (ERF-1, cMG1) Gene Induces Myeloid Cell Proliferation in Response to G-CSF.
  • 2005/11 - 慶應医学会 三四会奨励賞 Analysis of Genes Under the Downstream Control of the t(8;21) Fusion Protein AML1-MTG8: Overexpression of the TIS11b (ERF-1, cMG1) Gene Induces Myeloid Cell Proliferation in Response to G-CSF.
  • 2005/11 - 平成17年度私立大学情報教育協会賞
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