Research keywords (3):
高次脳機能障害
, アルツハイマー病
, Alzheimer disease
Research theme for competitive and other funds (19):
2022 - 2025 白質から老化を制御する:脳アンチエイジング新戦略
2018 - 2023 Tau pathology associated from cerebral amyloid angiopathy by molecular PET images and CSF analyses
2019 - 2022 脳内免疫老化チェックポイントを起点とした健康長寿脳の実現
2017 - 2020 Effects of autophagy on neurofibrilary tangle formation: a role of granulovacular degeneration and sialylation
2014 - 2017 seeking the role of granulovacuolar degeneration in neurodegeneration
2014 - 2017 Elucidation of cognitive functions and molecular pathogenesis in Alzheimer's disease by CSF and PiB-PET
2011 - 2013 Analysis of molecular functions of presenilin in CSF phosphorylation of tau
2011 - 2013 Roles of granulovacuolar degeneration in neurodegenerative diseases
2005 - 2006 Study of cholesterol roles on neuronal maintenance
2004 - 2006 Research on cerebral beta-amyloid deposition and neurodegeneration related to lipid metabolism of the plasma membrane.
2003 - 2004 Mechanisms causing sporadic Alzheimer disease from a point of HDL deposition disorders
2000 - 2004 Hyperphosphorylation and aggregation of tau protein, and neuronal death
2001 - 2002 Cholesterol metabolism and Amyloid βprotein synthesis : Attention to Niemann-Pick discase type C
1999 - 2000 Searching Production sites of amyloid β protein : Special attention to RAFT
1997 - 1998 Amyloid beta protein deposition : cause or consequence of neuronal loss?
1997 - 1997 アミロイドβ蛋白の分泌におけるカルパイン-カルパスタチン系の関与
1996 - 1996 アルツハイマー病脳における細胞内アミロイドβ蛋白産生部位の同定
1996 - 1996 アミロイドβ蛋白切り出しに関与するプロテアーゼの細胞内局在
1995 - 1996 Studies on beta-amyloidogenesis-isolation of membrane-bound Abeta
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Papers (34):
Makoto Shibata, Koki Makioka, Takumi Nakamura, Hiroo Kasahara, Tsuneo Yamazaki, Masamitsu Takatama, Koichi Okamoto, Yoshio Ikeda. Role of complement activation and disruption of the blood-brain barrier in the pathogenesis of multiple system atrophy. Neuroscience letters. 2024. 822. 137642-137642
NOGUCHI Naoto, LEE Bumsuk, KONDO Ken, TESHIMA Ryoto, YAMAZAKI Tsuneo. Coordination of Hand Intrinsic Muscles during Precision Grasp in Cervical Myelopathy. 日本作業療法学会抄録集(CD-ROM). 2021. 55th