Murakami Yota

ムラカミヨウタ | Murakami Yota

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://wwwchem.sci.hokudai.ac.jp/~bo/

Research field (2)： Genetics , Genetics

Research keywords (11)： chromosome replication , epigenetics , ヘテロクロマチン , セントロメア , 染色体分配 , クロマチン構造 , Heterochromatin , Centromere , Chromosome segregation , Chromatin structure , Chromosomal replication

Research theme for competitive and other funds (39)：

2019 - 2024 ヒストン修飾Eraserによる抑制的エピゲノムの維持・変動制御機構の解明
2021 - 2023 エピジェネティック変異の多様性増大を介した環境適応機構の探索
2019 - 2022 Analysis of total regulatory mechanism of gene expression mediated by transcription speed control
2018 - 2020 Analysis of adaptive mutation induced by epeigenetic mutation
2016 - 2018 Screening of no-coding RNA that can control transcription and chromatin

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Papers (65)：

Tetsuya Yamamoto, Takahiro Asanuma, Yota Murakami. Polymeric nature of tandemly repeated genes enhances assembly of constitutive heterochromatin in fission yeast. Communications Biology. 2023. 6. 1
Shinya Takahata, Yota Murakami. Opposing Roles of FACT for Euchromatin and Heterochromatin in Yeast. Biomolecules. 2023. 13. 2
Taichi Bun, Yuta Sato, Hajime Futami, Yuki Tagawa, Yota Murakami, Masayuki Takahashi. Cytoskeletal fractionation identifies LMO7 as a positive regulator of fibroblast polarization and directed migration. Biochemical and Biophysical Research Communications. 2023. 638. 58-65
Takahiro Asanuma, Soichi Inagaki, Tetsuji Kakutani, Hiroyuki Aburatani, Yota Murakami. Tandemly repeated genes promote RNAi-mediated heterochromatin formation via an antisilencing factor, Epe1, in fission yeast. Genes & Development. 2022
Satoru Tsunemine, Hiromi Nakagawa, Yutaka Suzuki, Yota Murakami. The chromatin remodeler RSC prevents ectopic CENP-A propagation into pericentromeric heterochromatin at the chromatin boundary. Nucleic Acids Research. 2022. 50. 19. 10914-10928

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MISC (24)：

Regulation of Chromatin structure by transcription machinery. 2017. 89. 3. 441-444
Takuya Kajitani, Hiroaki Kato, Yuji Chikashige, Hiroshi Kimura, Yasuyuki Ohkawa, Damien Herand, Yota Murakami. Phosphorylation at Ser7 of RNA polymerase II CTD limits transcription speed and transcription elongation. GENES & GENETIC SYSTEMS. 2016. 91. 6. 348-348
Takuya Kajitani, Hiroaki Kato, Yuji Chikashige, Yasushi Hiraoka, Hiroshi Kimura, Yasuyuki Ohkawa, Damien Hermand, Yota Murakami. Phosphorylation at Ser7 of RNAPII-CTD ensures on-chromatin retention of nascent ncRNAs, triggering RNAi-dependent heterochromatin formation. GENES & GENETIC SYSTEMS. 2014. 89. 6. 331-331
Kei Kawakami, Aki Hayashi, Jun-ichi Nakayama, Yota Murakami. A novel RNAi protein, Dsh1, assembles RNAi machinery on chromatin to amplify heterochromatic siRNA (vol 26, pg 1811, 2012). GENES & DEVELOPMENT. 2012. 26. 19. 2251-2251
Hidetsugu Kohzaki, Yota Murakami. A transcription factor Abf1 facilitates ORC binding onto the Saccharomyces cerevisiae replication origin via histone acetylase Gcn5. GENES & GENETIC SYSTEMS. 2011. 86. 6. 383-383

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Education (4)：

Kyoto University Faculty of Science
京都大学理学研究科
Kyoto University, Faculty of Science
Kyoto University, Graduate School of Science

Professional career (1)：

Ph.D.

Work history (10)：

2009/04 - 現在 Faculty of Science, Hokkaido University Professor
1993/10 - 現在 Associate Professor,
1993/10 - 2009/03 Institute for Virus Research, Kyoto University Associate Professor
1990/10 - 1993/10 米国スローン・ケタリング記念がんセンター
1990/10 - 1993/10 Memorial Sloan-Keetering Cancer Center(USA),

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Association Membership(s) (4)：

エピジェネティクス研究会 , JAPAN SOCIETY FOR CELL BIOLOGY , 分子生物学会 , The Molecular Biology Society of Japan

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