Research field (1)：
Environmental effects of chemicals
Research keywords (9)：
neurological abnormality
, solar UV-induced skin cancer
, xeroderma pigmentosum
, DNA repair deficient disorder
, nucleotide excision repair
, oxidatively generated DNA damage cyclopurine
, UV-induced pyrimidine dimer
, monoclonal antibody against DNA damage
, DNA damage and repair
Research theme for competitive and other funds (13)：
2020 - 2024 腎疾患における酸化ストレス評価法の開発と新規治療戦略および基盤概念の提唱
2020 - 2023 ヒト脳オルガノイドを用いた色素性乾皮症A群患者の進行性神経障害の機構解析
2020 - 2023 酸化的 DNA 損傷に対する人為的な修復亢進ー色素性乾皮症治療を目指してー
2004 - 2005 Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -
2004 - 2005 How do DNA repair-deficient trichothiodystrophy patients escape ultraviolet-light-induced skin cancers?
2003 - 2004 Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells
2002 - 2003 Trichothiodystrophy fibroblasts are deficient in the repair of ultraviolet-induced cyclobutane pyrimidine dimers and (6-4) photoproducts
1995 - 1995 紫外線による遺伝子損傷の誘発と内在性メラニンによる防御の証明と定量化
1993 - 1993 紫外線による細胞内DNA損傷の誘発と内在性メラニンによる防御の定量化
1992 - 1992 XP-A細胞の紫外線高感受性の原因となる二つめの修復遺伝子
1990 - 1991 Are (6-4) photoproducts the main ultraviolet-induced lethal lesions?
1990 - 1991 The Studies on The Repair of DNA Damage Induced in Human Cells Irradiated with Ultraviolet Light (UV).
1988 - 1988 がん遺伝子検出に使用する新しい細胞系の開発
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Papers (127)：
Kazuki Nishimura, Hironobu Ikehata, Thierry Douki, Jean Cadet, Shigeki Sugiura, Toshio Mori. Seasonal Differences in the UVA/UVB Ratio of Natural Sunlight Influence the Efficiency of the Photoisomerization of (6-4) Photoproducts into their Dewar Valence Isomers. Photochemistry and photobiology. 2020
Ikehata H, Mori T, Kamei Y, Douki T, Cadet J, Yamamoto M. Wavelength- and Tissue-dependent Variations in the Mutagenicity of Cyclobutane Pyrimidine Dimers in Mouse Skin. Photochem Photobiol. 2019. php.13159
T. Mori, H. Nakane, T. Iwamoto, M.G. Krokidis, C. Chatgilialoglu, K. Tanaka, T. Kaidoh, M. Hasegawa, S. Sugiura. High levels of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine accumulate in the brain tissues of xeroderma pigmentosum group A gene-knockout mice. DNA Repair. 2019. 80. 52-58
Tomoko Ishikawa-Fujiwara, Eri Shiraishi, Yoshihiro Fujikawa, Toshio Mori, Tohru Tsujimura, Takeshi Todo. Targeted Inactivation of DNA Photolyase Genes in Medaka Fish (Oryzias latipes). PHOTOCHEMISTRY AND PHOTOBIOLOGY. 2017. 93. 1. 315-322
Kanya Honoki, Hiromasa Fujii, Akira Kido, Shinji Tsukamoto, Toshio Mori, Yasuhito Tanaka, Toshifumi Tsujiuchi. Possible involvement of senescence bypass in mesenchymal stem cells for sarcomagenesis identified through a comparative gene expression profiling in rat sarcoma model. CANCER RESEARCH. 2015. 75
K. Honoki, H. Fujii, Y. Tohma, A. Kido, S. Tsukamoto, Y. Kondo, T. Mori, T. Tsujiuchi, Y. Tanaka. Role of Mesenchymal Stem Cells as a Co-conspirator for Tumour Progression in Syngeneic Rat Osteosarcoma Model: a Comparative Analysis of Gene Expression Profiles for Tumour Progression. EUROPEAN JOURNAL OF CANCER. 2012. 48. S30-S30
