Rchr
J-GLOBAL ID：200901067151222930   Update date: Jun. 30, 2024

SHINDO Kazutoshi

シンドウ カズトシ | SHINDO Kazutoshi
Affiliation and department：
JApan Women's University Faculty of Human Sciences and Design Department of Food and Nutrition

About JApan Women's University Faculty of Human Sciences and Design Department of Food and Nutrition


Job title： Professor
Homepage URL  (1)： http://mcm-www.jwu.ac.jp/~kshindo/index.htm
Research field  (2)： Analytical chemistry ,  Bioorganic chemistry
Research keywords  (3)： Carotenoid ,  Biotransformation ,  Natural-product Chemistry
Research theme for competitive and other funds  (11)：
  • 2022 - 2025 Search for bioactive compounds produced by cooking and preservation processes.
  • 2019 - 2022 Studies on pharmaceutical activities on cis carotenoids contained in foods.
  • 2015 - 2019 Studies on pharmaceutical activities produced by heat treatment of foods
  • 2013 - 2017 Development of the production system of functional carotenoids rare in nature using chloroplast-genome modified lettuce
  • 2013 - 2016 Effect of new ellagitannin, Zeylaniin A, on lifestyle related disease
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Papers (148)：
  • Wataru Matsumoto, Miho Takemura, Haruka Nanaura, Yuta Ami, Takashi Maoka, Kazutoshi Shindo, Shin Kurihara, Norihiko Misawa. Carotenoid productivity in human intestinal bacteria Eubacterium limosum and Leuconostoc mesenteroides with functional analysis of their carotenoid biosynthesis genes. Engineering Microbiology. 2024
  • Maho Shimagami, Maho Sugaya, Hinako Kimura, Kazutoshi Shindo. Identification of bolegrevilol B and C as novel antioxidant compounds in Suillus grevillei mushroom. Bioscience, Biotechnology, and Biochemistry. 2023
  • Moe Hagiwara, Chinatsu Maehara, Miho Takemura, Norihiko Misawa, Kazutoshi Shindo. Production of Highly Modified C30-carotenoids with Singlet Oxygen-quenching Activities, 5-glucosyl-5,6-dihydro-4,4’-diapolycopen-4’-oic Acid, and Its Three Intermediates Using Genes from Planococcus maritimus Strain iso-3. Synthetic Biology and Engineering. 2023. 1. 1. 1-12
  • Shun Saito, Kayo Funayama, Wataru Kato, Mayu Okuda, Meiko Kawamoto, Teruhiko Matsubara, Toshinori Sato, Akihiko Sato, Satoko Otsuguro, Michihito Sasaki, et al. Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses. Journal of Natural Products. 2022. 85. 11. 2583-2591
  • Shota Uesugi, Mayuka Hakozaki, Yuko Kanno, Yuta Takahashi, Kazutoshi Shindo, Ken-ichi Kimura, Akira Yano. Anti-melanogenic effect of furanoeremophilanes identified from edible wild plants belonging to the genus Cacalia. Bioscience, Biotechnology, and Biochemistry. 2022. 86. 10. 1462-1466
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MISC (6)：
  • Higuchi,Yuki, Hattan,Jun-ichiro, Ohno,Fumina, Ito,Tomoko, Shibuya,Yurika, Watanabe,Arisa, Ishii,Jun, Kondo,Akihiko, Shindo,Kazutoshi, Misawa,Norihiko. 2P-111 Isolation and functional analysis of a novel sesquiterpene synthase gene from Freesia X hybrida 'Ishikawa f1'. 2015. 67. 202
  • Kazutoshi Shindo, Megumi Endo, Yuriko Miyake, Kyoko Wakasugi, David Morritt, Peter M. Bramley, Paul D. Fraser, Hiroaki Kasai, Norihiko Misawa. Methyl 5-glucosyl-5,6-dihydro-apo-4,4 '-lycopenoate, a novel antioxidative glyco-C-30-carotenoic acid produced by a marine bacterium Planococcus maritimus (vol 61, pg 729, 2008). JOURNAL OF ANTIBIOTICS. 2014. 67. 10. 731-732
  • Tatsuro Kawamura, Kohei Matsubara, Hitomi Otaka, Etsu Tashiro, Kazutoshi Shindo, Ryo C. Yanagita, Kazuhiro Irie, Masaya Imoto. Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP (vol 19, pg 4377, 2011). BIOORGANIC & MEDICINAL CHEMISTRY. 2012. 20. 7. 2479-2479
  • Al Rahim Md., 中島 晶, 三沢 典彦, 新藤 一敏, 足立 恭子, 志津里 芳一, 音松 俊彦, 大泉 康, 山國 徹. 培養ラット海馬ニューロンにおいて、微生物変換によって合成された新規chalcone-diolは、Abeta誘発性のPKA依存的シグナル伝達阻害を抑制する. 日本薬学会年会要旨集. 2008. 128年会. 3. 11-11
  • MARUYAMA Takahiro, ISHIKURA Masaharu, TAKI Hironori, SHINDO Kazutoshi, KANOH Kaneo, IKENAGA Hiroshi, MISAWA Norihiko. 2K14-3 Isolation and characterization of a novel o-xylene oxygenase genes from Rhodococcus opacus strain TKN14. 2004. 16. 250-250
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Patents (11)：
  • 新規カロテノイド化合物
  • 活性酸素消去剤
  • カルコン配糖体を含む抗酸化剤
  • カカロールを含む植物抽出液の製造方法およびカカロールを含む植物抽出物を有効成分とするコラーゲン産生促進剤
  • キク科植物の抽出物を含有する賦活化剤
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Books (10)：
  • 有機化学の基礎
    東京化学同人 2021 ISBN:9784807916771
  • 図解 食品学実験
    アイ・ケイ・コーポレーション 2018
  • 食品分析化学
    東京化学同人 2016
  • 食品の保健機能と生理学
    2015
  • 基礎分析学
    2006
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Works (1)：
  • 組換え微生物を用いた代謝系遺伝子の機能解析 2002-2004
Education (2)：
  • - 1987 The University of Tokyo Graduate School, Division of Agricultural Science
  • - 1985 The University of Tokyo Faculty of Agriculture
Professional career (1)：
  • 農学博士 (東京大学)
Work history (1)：
  • 1987 - 2002 キリンビール(株)勤務
Association Membership(s) (5)：
日本家政学会 ,  日本カロテノイド学会 ,  日本栄養・食糧学会 ,  日本放線菌学会 ,  日本農芸化学会
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