Rchr
J-GLOBAL ID：200901067151877937
Update date: Feb. 01, 2024
Taniguchi Yosuke
タニグチ ヨウスケ | Taniguchi Yosuke
Affiliation and department：
Job title：
Graduate student
Homepage URL (1)：
http://bioorg.phar.kyushu-u.ac.jp/
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (5)：
WNA
, nucleoside analogue
, antigene
, Triplex
, triplex
Research theme for competitive and other funds (14)：
- 2020 - 2024 脳疾患部位を標的とする先端的核酸デリバリー技術の確立と脳疾患治療への挑戦
- 2019 - 2023 Development of artificial nucleoside analogues for the duplex DNA recognition, and antigene oligonucleotides
- 2017 - 2020 Development of novel gene detection method using artificial nucleic acid capable of recognizing damaged bases
- 2016 - 2019 Examination of oligonucleotide therapeutics based on the triplex DNA formation by artificial oligonucleotide
- 2015 - 2018 Chemically reactive oligonucleotides for site-specific modification of RNA and artificial RNA editing
- 2014 - 2017 Development of CpG island binding molecule based on artificial dinucleotide
- 2012 - 2016 Development of antigene strategy by triplex forming oligonucleotides having artificial nucleoside analogues
- 2012 - 2014 Development of the recognition molecule for 8-oxo-rG in RNA
- 2008 - 2009 Development of the nucleoside analogs to harmonize with in vivo molecular function
- 2007 - 2008 タンパク質との機能融合を目指したゲノム標的機能性人工核酸の開発
- 2005 - 2008 Development of Genome-Targeting Molecules with Ability of Chemical Reactivity and Application to Intelligent Nano-Medicine
- 2005 - 2006 3本鎖認識コードの拡張を目的とする人工ヌクレオシドの創製
- 3本鎖DNA形成を可能にする人工核酸の開発
- Synthesis of the W-shaped nucleoside analogues
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Papers (80)：
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Hirotaka Murase, Jeongsu Lee, Yosuke Taniguchi, Shigeki Sasaki. Site-Specific Tritium Labeling at the Predefined Internal Position of the Chemically-Modified RNA. Chemical and Pharmaceutical Bulletin. 2023. 71. 1. 64-69
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Ryotaro Notomi, Shigeki Sasaki, Yosuke Taniguchi. Recognition of 5-methyl-CG and CG base pairs in duplex DNA with high stability using antiparallel-type triplex-forming oligonucleotides with 2-guanidinoethyl-2'-deoxynebularine. Nucleic acids research. 2022
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Junjie Wu, Mengmeng Zhang, Lulu Song, Yahong Tan, Yosuke Taniguchi, Christopher John Hipolito, Youming Zhang, Yizhen Yin. Implications of N7-hydrogen and C8-keto on the base pairing, mutagenic potential and repair of 8-oxo-2'-deoxy-adenosine: Investigation by nucleotide analogues. BIOORGANIC CHEMISTRY. 2022. 127
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Ryo Miyahara, Yosuke Taniguchi. Selective Unnatural Base Pairing and Recognition of 2-Hydroxy-2'-deoxyadenosine in DNA Using Pseudo-dC Derivatives. Journal of the American Chemical Society. 2022. 144. 35. 16150-16156
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Daijiro Hori, Yohei Nomura, Yosuke Taniguchi, Koichi Yuri, Makiko Mieno, Naoyuki Kimura, Atsushi Yamaguchi. The effect of stent and decalcification on mitral annular motion after aortic valve replacement. JOURNAL OF CARDIAC SURGERY. 2022. 37. 9. 2706-2712
ｍore...
MISC (2)：
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Y Taniguchi, A Nakamura, Y Senko, F Nagatsugi, S Sasaki. Effects of halogenated WNA derivatives on sequence dependency for expansion of recognition sequences in non-natural-type triplexes. JOURNAL OF ORGANIC CHEMISTRY. 2006. 71. 5. 2115-2122
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Y Taniguchi, S Sasaki. Development of novel artificial nucleosides for expansion of triplex-recognition codes. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN. 2004. 62. 10. 1026-1037
Professional career (1)：
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